Results 171 to 180 of about 20,465 (247)

The kallikrein world: an update on the human tissue kallikreins

Biological Chemistry, 2006
Human tissue kallikreins (hKs) are attracting increased attention owing to their association with various forms of cancer and other diseases. Human tissue kallikrein genes represent the largest contiguous group of proteases within the human genome. There are many areas of kallikrein research that need to be further explored, including their tissue ...
M. Paliouras, E. Diamandis
semanticscholar   +3 more sources

Human tissue Kallikreins: Blood levels and response to radiotherapy in intermediate risk prostate cancer

Radiotherapy and Oncology, 2017
Eleftherios Diamandis, , Antoninus Soosaipillai   +2 more
exaly   +2 more sources

Human Kallikrein 2 (hK2) and Prostate-Specific Antigen (PSA): Two Closely Related, but Distinct, Kallikreins in the Prostate

Critical Reviews in Clinical Laboratory Sciences, 1998
Alan W Partin, Judith A Finlay, Stephen D Mikolajczyk   +2 more
exaly   +2 more sources

Human tissue kallikreins: The cancer biomarker family

Cancer Letters, 2007
Eleftherios Diamandis, Miltiadis Paliouras   +1 more
exaly   +2 more sources

Cellular distribution of human tissue kallikreins: immunohistochemical localization

Biological Chemistry, 2006
Eleftherios Diamandis, Vassiliki Karavana, Constantina D Petraki   +2 more
exaly   +2 more sources

Proteinase-mediated cell signalling: targeting proteinase-activated receptors (PARs) by kallikreins and more

Biological Chemistry, 2006
Eleftherios Diamandis, Nathalie Vergnolle, Morley Hollenberg   +2 more
exaly   +2 more sources

The role of kallikreins in inflammatory skin disorders and their potential as therapeutic targets

Critical reviews in clinical laboratory sciences, 2020
The skin is a vital organ of the human body, serving numerous protective and functional roles that are essential for survival. Residing in the epidermis are various epidermal proteases responsible for the establishment and regulation of barrier function.
Caitlin T. Di Paolo, E. Diamandis, I. Prassas   +2 more
semanticscholar   +1 more source

Specificity of potato kallikrein inhibitors for kallikreins

Experientia, 1970
Two polyvalent protease inhibitors, acting especially on plasma kallikrein, were isolated from potatoes. Some of their physicochemical and biological properties were investigated.
H, Moriya, Y, Hojima, C, Moriwaki, T, Tajima   +3 more
openaire   +2 more sources

Mesenchymal stem cells differentiate into keratinocytes and express epidermal kallikreins: Towards an in vitro model of human epidermis

Journal of Cellular Biochemistry, 2019
Epidermal differentiation is a complex process in which keratinocytes go through morphological and biochemical changes in approximately 15 to 30 days. Abnormal keratinocyte differentiation is involved in the pathophysiology of several skin diseases.
Jeniffer Farias dos Santos, Nathália Ruder Borçari, Mariana da Silva Araújo, V. A. Nunes   +3 more
semanticscholar   +1 more source

Toward the first class of suicide inhibitors of kallikreins involved in skin diseases.

Journal of Medicinal Chemistry, 2015
The inhibition of kallikreins 5 and 7, and possibly kallikrein 14 and matriptase, (that initiates the kallikrein proteolytic cascade) constitutes an innovative way to treat some skin diseases such as Netherton syndrome.
Xiao Tan, Feryel Soualmia, L. Furio, J. Renard, I. Kempen, L. Qin, M. Pagano, B. Pirotte, C. El Amri, A. Hovnanian, M. Reboud-Ravaux   +10 more
semanticscholar   +1 more source