Results 11 to 20 of about 5,941 (171)

Hypoxic reactivation of Kaposi's sarcoma associated herpesvirus

Cell Insight
Hypoxic reactivation of Kaposi's sarcoma-associated herpesvirus (KSHV) refers to the phenomenon under low oxygen where the virus goes from latent to lytic replication.
Rajnish Kumar Singh, Atharva S. Torne, Erle S. Robertson   +2 more
doaj   +3 more sources

Targeting Kaposi’s sarcoma associated herpesvirus encoded protease (ORF17) by a lysophosphatidic acid molecule for treating KSHV associated diseases

Frontiers in Cell and Developmental Biology, 2023
Kaposi’s sarcoma associated herpesvirus (KSHV) is causative agent of Kaposi’s sarcoma, Multicentric Castleman Disease and Pleural effusion lymphoma. KSHV-encoded ORF17 encodes a protease which cleaves -Ala-Ala-, -Ala-Ser- or -Ala-Thr-bonds.
Misbahuddin M Rafeeq, Alaa Hamed Habib, Alaa F. Nahhas, Najat Binothman, Majidah Aljadani, Jawaher Almulhim, Ziaullah M Sain, Mohammad Zubair Alam, Mohammad Zubair Alam, Norah A Alturki, Qamre Alam, Manish Manish, Rajnish Kumar Singh   +12 more
doaj   +1 more source

Mycosis fungoides and Kaposi’s sarcoma association in an HIV-negative patient [PDF]

Anais Brasileiros de Dermatologia, 2016
The association of mycosis fungoides and kaposi’s sarcoma in HIV-negative patients is a rare phenomenon. The presence of human herpesvirus 8 (HHV-8) – associated with all forms of Kaposi’s sarcoma – has also been recently identified in mycosis fungoides ...
Maria Carolina Prado Fleury Bariani, Luiz Fernando Fróes Fleury Júnior, Ana Maria Quinteiro Ribeiro, Siderley de Souza Carneiro, Tiago Arantes Pereira   +4 more
doaj   +1 more source

Kaposi’s sarcoma associated with chronic myeloid leukemia and imatinib mesylate therapy

Clinical Case Reports, 2022
Kaposi's sarcoma is associated with immunosuppression and human herpesvirus 8 infection, while rarely described in myeloid malignancies. Here, we illustrate a rare case of chronic myeloid leukemia treated with imatinib, a tyrosine kinase inhibitor, who ...
Matteo D’Addona, Luca Pezzullo, Valentina Giudice, Bianca Serio, Carlo Baldi, Pio Zeppa, Carmine Selleri   +6 more
doaj   +1 more source

Pulmonary Kaposi's sarcoma—an atypical clinical presentation

International Journal of Infectious Diseases, 2022
HIV-associated Kaposi's sarcoma is an angioproliferative neoplasia caused by infection with human herpesvirus 8. It typically presents with mucocutaneous involvement. Pulmonary Kaposi's sarcoma is rare, and an uncommon form of initial presentation of the
Ana Luísa Ramos, Joana Granado, Ana Isabel Calderón, Sandra André, Fernando Nogueira   +4 more
doaj   +1 more source

Kaposi's Sarcoma-Associated Herpesvirus [PDF]

Current Opinion in Infectious Diseases, 2015
To discuss the role of Kaposi's sarcoma-associated herpesvirus (KSHV) lytic replication in viral-associated diseases and assess the progress on targeting KSHV lytic replication as a strategy to prevent KSHV-related malignancies.New inhibitors of viral lytic replication are being developed as well as novel modalities are being investigated to target ...
Graciela, Andrei, Robert, Snoeck
openaire   +3 more sources

Angiogenesis, Kaposi’s sarcoma and Kaposi’s sarcoma-associated herpesvirus [PDF]

Virologica Sinica, 2008
Tumor angiogenesis is the uncontrolled growth of blood vessels in tumors, serving to supply nutrients and oxygen, and remove metabolic wastes. Kaposi's sarcoma (KS), a multifocal angioproliferative disorder characterized by spindle cell proliferation, neo-angiogenesis, inflammation, and edema, is associated with infection by Kaposi's sarcoma-associated
Tao, Kang, Feng-Chun, Ye, Shou-Jiang, Gao, Lin-Ding, Wang   +3 more
openaire   +2 more sources

Insight into the Epigenetics of Kaposi's Sarcoma Associated Herpesvirus

International Journal of Molecular Sciences, 2023
Epigenetic reprogramming represents a series of essential events during many cellular processes including oncogenesis. Genome of Kaposi’s sarcoma-associated herpesvirus (KSHV), an oncogenic herpesvirus is predetermined for a well-orchestrated epigenetic reprogramming once it enters into a host cell.
Srivastava, Anusha, Srivastava, Ankit, Singh, Rajnish Kumar   +2 more
openaire   +2 more sources

The Ubiquitin System and Kaposi’s Sarcoma-Associated Herpesvirus [PDF]

Frontiers in Microbiology, 2012
Ubiquitination is a post-translational modification in which one or more ubiquitin molecules are covalently linked to lysine residues of target proteins. The ubiquitin system plays a key role in the regulation of protein degradation, which contributes to cell signaling, vesicular trafficking, apoptosis, and immune regulation.
Akira eAshizawa, Chizuka eHigashi, Kazuki eMasuda, Rie eOhga, Takahiro eTaira, Masahiro eFujimuro, Masahiro eFujimuro   +6 more
openaire   +3 more sources

KSHV/HHV-8 and HIV infection in Kaposi's sarcoma development [PDF]

, 2007
Kaposi's sarcoma (KS) is a highly and abnormally vascularized tumor-like lesion affecting the skin, lymphnodes and viscera, which develops from early inflammatory stages of patch/plaque to late, nodular tumors composed predominant of spindle cells (SC ...
Pyakurel, P., Pak, F., Mwakigonja, A.R, Kaaya, E., Biberfeld, P.   +4 more
core   +1 more source