Kaposi’s sarcoma associated with chronic myeloid leukemia and imatinib mesylate therapy
Clinical Case Reports, 2022 Kaposi's sarcoma is associated with immunosuppression and human herpesvirus 8 infection, while rarely described in myeloid malignancies. Here, we illustrate a rare case of chronic myeloid leukemia treated with imatinib, a tyrosine kinase inhibitor, who ...
Matteo D’Addona +6 more
doaj +1 more source
Pulmonary Kaposi's sarcoma—an atypical clinical presentation
International Journal of Infectious Diseases, 2022 HIV-associated Kaposi's sarcoma is an angioproliferative neoplasia caused by infection with human herpesvirus 8. It typically presents with mucocutaneous involvement. Pulmonary Kaposi's sarcoma is rare, and an uncommon form of initial presentation of the
Ana Luísa Ramos +4 more
doaj +1 more source
Angiogenesis, Kaposi’s sarcoma and Kaposi’s sarcoma-associated herpesvirus [PDF]
Virologica Sinica, 2008 Tumor angiogenesis is the uncontrolled growth of blood vessels in tumors, serving to supply nutrients and oxygen, and remove metabolic wastes. Kaposi's sarcoma (KS), a multifocal angioproliferative disorder characterized by spindle cell proliferation, neo-angiogenesis, inflammation, and edema, is associated with infection by Kaposi's sarcoma-associated
Tao, Kang +3 more
openaire +2 more sources
The cellular paraspeckle component SFPQ associates with the viral processivity factor ORF59 during lytic replication of Kaposi's Sarcoma-associated herpesvirus (KSHV). [PDF]
Virus ResPayen SH +5 more
europepmc +2 more sources
The Ubiquitin System and Kaposi’s Sarcoma-Associated Herpesvirus [PDF]
Frontiers in Microbiology, 2012 Ubiquitination is a post-translational modification in which one or more ubiquitin molecules are covalently linked to lysine residues of target proteins. The ubiquitin system plays a key role in the regulation of protein degradation, which contributes to cell signaling, vesicular trafficking, apoptosis, and immune regulation.
Akira eAshizawa +6 more
openaire +3 more sources
Vertical transmission of Kaposi's sarcoma-associated herpesvirus [PDF]
International Journal of Cancer, 2001 Little is presently known about the specific routes of transmission of Kaposi's sarcoma-associated herpesvirus (KSHV) or human herpesvirus-8 (HHV-8). To investigate whether this agent might be transmitted vertically from mother to infant, we conducted a study on 89 KSHV seropositive mothers and their newborn infants.
Mantina, Hamakwa +9 more
openaire +3 more sources
NEDDylation is essential for Kaposi's sarcoma-associated herpesvirus latency and lytic reactivation and represents a novel anti-KSHV target. [PDF]
, 2015 Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi's sarcoma (KS) and primary effusion lymphoma (PEL), which are aggressive malignancies associated with immunocompromised patients.
Wood, Jennifer J +19 more
core +1 more source
High-density resolution of the Kaposi's sarcoma associated herpesvirus transcriptome identifies novel transcript isoforms generated by long-range transcription and alternative splicing. [PDF]
Nucleic Acids ResShekhar R +7 more
europepmc +2 more sources
Killing of Kaposi's sarcoma-associated herpesvirus-infected fibroblasts during latent infection by activated natural killer cells. [PDF]
, 2011 Kaposi's sarcoma-associated herpesvirus (KSHV) establishes life-long infection by evading clearance by the host immune system. In de novo infection and lytic replication, KSHV escapes cytotoxic T cells and NK cells through downregulation of MHC class-I ...
Nick C. Matthews +14 more
core +1 more source
Kaposi's sarcoma-associated herpesvirus replication and transcription activator protein activates CD274/PD-L1 gene promoter. [PDF]
Cancer Sci, 2023 Miyazawa M +4 more
europepmc +3 more sources