Results 31 to 40 of about 7,810 (157)

Epigenetic Landscape of Kaposi's Sarcoma-Associated Herpesvirus Genome in Classic Kaposi's Sarcoma Tissues. [PDF]

PLoS Pathogens, 2017
Kaposi's sarcoma-associated herpesvirus (KSHV) is etiologically related to Kaposi's sarcoma (KS), primary effusion lymphoma (PEL) and multicentric Castleman's disease (MCD).
Rui Sun, Xiaohua Tan, Xing Wang, Xiaodong Wang, Lei Yang, Erle S Robertson, Ke Lan   +6 more
doaj   +1 more source

Modulation of immune system by Kaposi’s sarcoma-associated herpesvirus:Lessons from viral evasion strategies

Frontiers in Microbiology, 2012
Kaposi’s sarcoma-associated herpesvirus (KSHV), a member of the herpesvirus family, has evolved to establish a long-term, latent infection of cells such that while they carry the viral genome gene expression is highly restricted.
Hye-Ra eLee, Kevin eBrulois, LaiYee eWong, Jae U. eJung   +3 more
doaj   +1 more source

Productively infected murine Kaposi's sarcoma-like tumors define new animal models for studying and targeting KSHV oncogenesis and replication. [PDF]

PLoS ONE, 2014
Kaposi's sarcoma (KS) is an AIDS-defining cancer caused by the KS-associated herpesvirus (KSHV). KS tumors are composed of KSHV-infected spindle cells of vascular origin with aberrant neovascularization and erythrocyte extravasation. KSHV genes expressed
Brittany M Ashlock, Qi Ma, Biju Issac, Enrique A Mesri   +3 more
doaj   +1 more source

Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections

Nature Communications, 2020
Disease prognosis after infection with Kaposi’s sarcoma-associated herpesvirus and Epstein-Barr Virus is highly variable. Here the authors carry out epidemiological and genetic analysis of a Ugandan cohort and suggest complex interactions may influence ...
Neneh Sallah, Wendell Miley, Nazzarena Labo, Tommy Carstensen, Segun Fatumo, Deepti Gurdasani, Martin O. Pollard, Alexander T. Dilthey, Alexander J. Mentzer, Vickie Marshall, Elena M. Cornejo Castro, Cristina Pomilla, Elizabeth H. Young, Gershim Asiki, Martin L. Hibberd, Manjinder Sandhu, Paul Kellam, Robert Newton, Denise Whitby, Inês Barroso   +19 more
doaj   +1 more source

The T-Cell Immune Response against Kaposi's Sarcoma-Associated Herpesvirus

Advances in Virology, 2010
Kaposi's sarcoma-associated herpesvirus (KSHV) is the aetiological agent of Kaposi's sarcoma (KS), the most frequently arising malignancy in individuals with untreated HIV/AIDS.
Rebecca C. Robey, Salvinia Mletzko, Frances M. Gotch   +2 more
doaj   +1 more source

Kaposi’s Sarcoma-Associated Herpesvirus-Encoded circRNAs Are Expressed in Infected Tumor Tissues and Are Incorporated into Virions

mBio, 2020
Kaposi’s sarcoma-associated herpesvirus (KSHV) has recently been found to generate circular RNAs (circRNAs) from several KSHV genes, most abundantly from K10 (viral interferon regulatory factor 4 [vIRF4]), K7.3, and polyadenylated nuclear (PAN) RNA.
Bizunesh Abere, Jinghui Li, Hongzhao Zhou, Tuna Toptan, Patrick S. Moore, Yuan Chang   +5 more
doaj   +1 more source

Kaposi’s sarcoma in AIDS patients: a case series

Przegląd Dermatologiczny
Kaposi’s sarcoma is a multifocal tumor of endothelial origin associated with human herpesvirus 8 infection. Lesions typically appear as patches, plaques, or hemorrhagic nodules.
Małgorzata Dominiak, Julia Domurad-Falenta, Aleksandra Lesiak, Joanna Narbutt   +3 more
doaj   +1 more source

Long Non-Coding RNA and Epigenetic Gene Regulation of KSHV

Viruses, 2014
Kaposi’s sarcoma-associated herpesvirus (KSHV/human herpesvirus 8) is a γ-herpesvirus linked to Kaposi’s sarcoma (KS) and two lymphoproliferative disorders, primary effusion lymphoma (PEL or body-cavity B-lymphoma [BCBL]) and a subset of Multicentric ...
Mel Campbell, Hsing-Jien Kung, Yoshihiro Izumiya   +2 more
doaj   +1 more source

KSHV Induction of Angiogenic and Lymphangiogenic Phenotypes

Frontiers in Microbiology, 2012
Kaposi’s Sarcoma is a highly vascularized tumor supporting large amounts of neo-angiogenesis. The major cell type in KS tumors is the spindle cell, a cell that expresses markers of lymphatic endothelium. KSHV, the etiologic agent of KS, is found in the
Terri A. DiMiao, Michael eLagunoff
doaj   +1 more source

Clinicoepidemiologic Profile of Oral Kaposi Sarcoma in People Living With HIV: A Systematic Review and Meta‐Analysis

Head &Neck, EarlyView.
ABSTRACT Background To characterize the clinicoepidemiologic profile of HIV‐associated oral Kaposi sarcoma (OKS) and quantitatively synthesize its frequency, anatomical distribution, and temporal patterns across antiretroviral therapy (ART) eras. Methods Six databases and gray literature were searched.
Ericles Otávio, Rebeca Ferreira Badaró, Daniel Pignatari Mahet Rodrigues, Giselle de Medeiros Silva, José Alcides Almeida de Arruda, Victor Zanetti Drumond, Jefferson R. Tenório, Lucas Alves Jural, Marcela Baraúna Magno, Lucianne Cople Maia, Bruno Augusto Benevenuto de Andrade   +10 more
wiley   +1 more source