Results 31 to 40 of about 5,941 (171)
Epigenetic diversity of Kaposi’s sarcoma–associated herpesvirus [PDF]
Nucleic Acids Research, 2013 Spontaneous lytic reactivation of Kaposi's sarcoma-associated herpesvirus (KSHV) occurs at a low rate in latently infected cells in disease and culture. This suggests imperfect epigenetic maintenance of viral transcription programs, perhaps due to variability in chromatin structure at specific loci across the population of KSHV episomal genomes.
Darst, Russell P. +4 more
openaire +2 more sources
Kaposi’s sarcoma with the eyelid involvement (6 clinical cases)
Alʹmanah Kliničeskoj Mediciny, 2018 Kaposi's sarcoma is a multifocal tumor from vascular endothelium with a low grade of malignancy. It develops due to underlying immune deficiency and is associated with human herpesvirus 8. Kaposi's sarcoma of the eyelids is rare, and its diagnosis can be
E. E. Grishina
doaj +1 more source
Role of the ubiquitin system and tumor viruses in AIDS-related cancer [PDF]
, 2007 Tumor viruses are linked to approximately 20% of human malignancies worldwide. This review focuses on examples of human oncogenic viruses that manipulate the ubiquitin system in a subset of viral malignancies; those associated with AIDS.
Joseph S Pagano, Julia Shackelford
core +2 more sources
RNAs in the Virion of Kaposi's Sarcoma-Associated Herpesvirus [PDF]
Journal of Virology, 2005 ABSTRACT De novo infection of cultured cells with Kaposi's sarcoma-associated herpesvirus (KSHV) typically results in a latent infection. Recently, however, it has been reported that a subset of lytic mRNAs can be detected in cells shortly after KSHV infection; this expression is transient and eventually subsides, leading to ...
Jill, Bechtel +2 more
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Fatal outcome in classic Kaposi's sarcoma [PDF]
, 2010 First described in 1872, Kaposi's sarcoma is defined as a rare multifocal tumor that originates in the endothelial cells and presents with cutaneous and extracutaneous manifestations. The classic form is most common in elderly men and progression is slow.
Almeida, Fernando Augusto de +4 more
core +3 more sources
NEDDylation is essential for Kaposi's sarcoma-associated herpesvirus latency and lytic reactivation and represents a novel anti-KSHV target. [PDF]
, 2015 Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi's sarcoma (KS) and primary effusion lymphoma (PEL), which are aggressive malignancies associated with immunocompromised patients.
A Sarikas +64 more
core +3 more sources
F1000Research, 2016 Kaposi’s sarcoma (KS)-associated herpesvirus (KSHV) is an oncogenic human herpesvirus. KSHV is associated with three cancers in the human population: KS, primary effusion lymphoma (PEL), and multicentric Castleman’s disease (MCD). KS is the leading cause
Nathan J. Dissinger, Blossom Damania
doaj +1 more source
Virion Proteins of Kaposi's Sarcoma-Associated Herpesvirus [PDF]
Journal of Virology, 2005 ABSTRACT The proteins that compose a herpesvirus virion are thought to contain the functional information required for de novo infection, as well as virion assembly and egress. To investigate functional roles of Kaposi's sarcoma-associated herpesvirus (KSHV) virion proteins in viral productive replication and de novo infection, we attempted ...
Fan Xiu, Zhu +3 more
openaire +2 more sources
mBio, 2011 Kaposi’s sarcoma (KS) is caused by Kaposi’s sarcoma-associated herpesvirus (KSHV; human herpesvirus 8). KS is an AIDS-defining cancer, and it is changing in the post-antiretroviral therapy (post-ART) era.
Dirk P. Dittmer
doaj +1 more source
Nature Communications, 2020 Disease prognosis after infection with Kaposi’s sarcoma-associated herpesvirus and Epstein-Barr Virus is highly variable. Here the authors carry out epidemiological and genetic analysis of a Ugandan cohort and suggest complex interactions may influence ...
Neneh Sallah +19 more
doaj +1 more source