Results 51 to 60 of about 5,941 (171)

Kaposi’s Sarcoma-Associated Herpesvirus-Encoded circRNAs Are Expressed in Infected Tumor Tissues and Are Incorporated into Virions

mBio, 2020
Kaposi’s sarcoma-associated herpesvirus (KSHV) has recently been found to generate circular RNAs (circRNAs) from several KSHV genes, most abundantly from K10 (viral interferon regulatory factor 4 [vIRF4]), K7.3, and polyadenylated nuclear (PAN) RNA.
Bizunesh Abere, Jinghui Li, Hongzhao Zhou, Tuna Toptan, Patrick S. Moore, Yuan Chang   +5 more
doaj   +1 more source

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

Advanced Science, EarlyView.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth, Christoph F. Jacob, Alexandra Nguyen, Mandy Beyer, Andreas O. Mieland, Mario Dejung, Jia‐Xuan Chen, Walburgis Brenner, Christina Ehrhardt, Andreas Henke, Oliver H. Krämer   +10 more
wiley   +1 more source

Prevalence of infection with human herpesvirus 8/Kaposi's sarcoma herpesvirus in rural South Africa [PDF]

, 1999
Objective. To determine prevalence of infection with human herpesvirus 8 (HHV-8)/Kaposi's sarcoma herpesvirus (KSHV) and to gain some insight into possible transmission dynamics of this novel virus in South Africa. Methods.
Gilks, C.F., Schulz, T.F., Sheldon, J., Wilkinson, D.   +3 more
core  

Constitutive activation of T cells by γ2-herpesviral GPCR through the interaction with cellular CXCR4 [PDF]

, 2017
Members of the herpesviral family use multiple strategies to hijack infected host cells and exploit cellular signaling for their pathogenesis and latent infection.
Aigerim, A, Cha, J.S, Cho, H.-S, Cho, N.-H., Choi, M.-S, Han, S.K, Kim, H, Kim, K, Kim, S, Kim, Y, Kwon, E.-K, Lee, J.-W, Min, C.-K, Nam, H.-J, Schmidt, S   +14 more
core   +1 more source

The HCMV‐encoded miR‐UL36‐3p promotes angiogenesis of endothelial cells by downregulating FOXO3

Animal Models and Experimental Medicine, EarlyView.
This illustration shows the role of hcmv‐miR‐UL36‐3p in endothelial cell angiogenesis. During productive infection, endothelial cells express HCMV‐encoded miRNAs. Viral hcmv‐miR‐UL36‐3p promotes endothelial cell proliferation, migration, and capillary tube formation by directly targeting and downregulating FOXO3. The pro‐angiogenic activity of hcmv‐miR‐
Chen Wang, Mengyu Li, Guosheng Li, Hao Zhang, Cheng Wang, Chen‐Yu Zhang   +5 more
wiley   +1 more source

Cancer risk in persons with HIV/AIDS in India: a review and future directions for research [PDF]

, 2009
Background India has a large and evolving HIV epidemic. Little is known about cancer risk in Indian persons with HIV/AIDS (PHA) but risk is thought to be low.
Robert J Biggar, Anil K Chaturvedi, Kishor Bhatia, Sam M Mbulaiteye   +3 more
core   +2 more sources

Integrative Assessment of Desmostachya bipinnata (L.) Root Extract: Anti‐Inflammatory and Antinociceptive Effects Supported by Molecular Docking and Network Pharmacology

Flavour and Fragrance Journal, EarlyView.
The ethanolic root extract of Desmostachya bipinnata exhibited significant anti‐inflammatory and antinociceptive activities in in vitro, in vivo and in silico models, revealing bioactive compounds capable of modulating key inflammatory targets and supporting the plant's traditional therapeutic potential.
Muhammad Hussnain Siddique, Muhammad Muzammil Nazir, Saima Muzammil, Iqra Farzeen, Shafaq Latif, Asma Ashraf, Jorddy Neves Cruz   +6 more
wiley   +1 more source

KSHV Induction of Angiogenic and Lymphangiogenic Phenotypes

Frontiers in Microbiology, 2012
Kaposi’s Sarcoma is a highly vascularized tumor supporting large amounts of neo-angiogenesis. The major cell type in KS tumors is the spindle cell, a cell that expresses markers of lymphatic endothelium. KSHV, the etiologic agent of KS, is found in the
Terri A. DiMiao, Michael eLagunoff
doaj   +1 more source

Cultured Kaposi's sarcoma tumor cells exhibit a chemokine receptor repertoire that does not allow infection by HIV-1 [PDF]

, 2001
SCOPUS: ar.jinfo:eu-repo/semantics ...
Thierry Simonart, Claire Debussher, Corinne Liesnard, Laurent Debaisieux, Marie-Luce Delforge, Aurore de Lavareille, Philippe Hermans, Jean-Paul Van Vooren, Patrick Stordeur, V Fiorelli, Y Chang, RC Gallo, K Murakami-Mori, B Ensoli, GD Kelly, P Delli Bovi, SE Mahoney, EE Kaaya, Y Lunardi-Iskandar, YQ Huang, BJ Nickoloff, S Uccini, T Simonart, AV Moses, RW Doms, Y Feng, A Borsetti, R Benelli, D Blankaert, T Simonart, AM Vandamme, K Van Laethem, DJ Dairaghi, SK Gupta, S Lee, M Stürlz   +35 more
core   +1 more source

Isolated Pleural Effusion as Presentation of a Large B‐Cell Lymphoma: A Case Report and Diagnostic Considerations

Journal of Clinical Laboratory Analysis, EarlyView.
A 79‐year‐old man presented with massive pleural effusion in which cytological examination revealed lymphoma cells without evidence of a solid tumor mass. Negative EBV in situ hybridization and negative HHV8 and HIV testing, combined with flow cytometric immunophenotyping and molecular findings, supported a diagnosis of fluid overload–associated large ...
Van Vlierberghe Magalie, Dewaide Rosina, Michaux Lucienne, Develter Wim, Van Aelst Sophie, Claerhout Helena   +5 more
wiley   +1 more source