Results 51 to 60 of about 7,810 (157)
Diagnostic Usefulness of Cell Block Samples in Fluid Overload‐Associated Large B‐Cell Lymphoma
ABSTRACT Fluid overload‐associated B‐cell lymphoma (FO‐LBCL) is a B‐cell neoplasm that presents as serous effusions without detectable tumor masses and Kaposi sarcoma‐associated herpesvirus (KSHV)/human herpesvirus 8 (HHV8) infection. Here, we report a case of an 81‐year‐old female patient with FO‐LBCL (Stage IVA) who presented with pericardial and ...
Hiroyuki Okanishi +14 more
wiley +1 more source
Kaposi's Sarcoma-Associated Herpesvirus-Related Solid Lymphoma Involving the Heart and Brain
Since its discovery in 1994, Kaposi's sarcoma-associated herpesvirus (KSHV) has been associated with lymphoproliferative disorders, particularly in patients infected with human ...
Jason R. Andrews +4 more
doaj +1 more source
EBV‑BZLF1 initiates ODC1‑driven polyamine anabolism that correlates with poor clinical prognosis in nasopharyngeal carcinoma. The ODC1–spermidine axis promotes viral replication, cell proliferation and innate immune evasion. Pharmacological inhibition of ODC1 rescues cisplatin sensitivity, establishing ODC1 as a viable therapeutic target for EBV ...
Yueshuo Li +9 more
wiley +1 more source
Targeted therapy for Kaposi's sarcoma and Kaposi's sarcoma-associated herpesvirus [PDF]
To summarize major recent findings on the biology of human herpesvirus-8, i.e. Kaposi’s sarcoma-associated herpesvirus, and the implications of these findings for Kaposi’s sarcoma treatment.
Dirk P, Dittmer, Susan E, Krown
openaire +2 more sources
HIV-negative disseminated Kaposi’s sarcoma in a Taiwanese patient
Kaposi’s sarcoma is a common malignancy associated with HIV/AIDS. Herein, we describe the case of a 26-year-old man who presented with bilateral neck and inguinal lymphadenopathy, a massive tumor on the gum, and a nodule over the left eye.
Chiung-Tang Huang +4 more
doaj +1 more source
Epigenetic Regulation of Kaposi’s Sarcoma-Associated Herpesvirus Latency
Kaposi’s sarcoma-associated herpesvirus (KSHV) is an oncogenic γ-herpesvirus that infects humans and exhibits a biphasic life cycle consisting of latent and lytic phases.
Mel Campbell +4 more
doaj +1 more source
An integrated computational and in vitro approach was used to investigate the anticancer activity of empagliflozin (EMPA) in A549 and HOP‐92 lung cancer cells and its interaction with hydroxychloroquine (HCQ). Network pharmacology identified 239 shared EMPA–lung cancer targets, while molecular docking predicted favorable interactions with ANXA8, SQSTM1/
Ola A. El‐Feky +6 more
wiley +1 more source
Kaposi‘s Sarcoma-Associated Herpesvirus and Innate Immunity [PDF]
Kaposi's sarcoma-associated herpesvirus (KSHV) is the most recently discovered human herpesvirus, first isolated and identified from a Kaposi's sarcoma lesion in 1994. It is the etiological agent of Kaposi's sarcoma, a vascular lesion that is the predominant cancer among AIDS patients. KSHV is also the primary etiological agent of two B-cell lymphomas,
John A, West, Blossom, Damania
openaire +2 more sources
Kaposi's sarcoma-associated herpesvirus encodes a functional cyclin [PDF]
Kaposi's sarcoma-associated herpesvirus (KSHV) (also called human herpesvirus 8) is consistently found in Kaposi's sarcoma lesions and in body-cavity-based lymphomas. A 17-kb KSHV lambda clone was obtained directly from a Kaposi's sarcoma lesion. DNA sequence analysis of this clone identified an open reading frame which has 32% amino acid identity and ...
M, Li +6 more
openaire +2 more sources
Unmasking the Influence of Viral Micro‐RNAs on Host Immunity
Viral micro‐RNAs are increasingly recognized as key modulators of host–virus interactions. They influence multiple immune functions, including antigen presentation, T‐cell activation, and cytokine signaling, while also tuning viral gene expression to promote persistence.
Riley J. K. Easton +1 more
wiley +1 more source

