Results 61 to 70 of about 8,087,253 (217)

Restricted Kaposi’s Sarcoma (KS) Herpesvirus Transcription in KS Lesions from Patients on Successful Antiretroviral Therapy

mBio, 2011
Kaposi’s sarcoma (KS) is caused by Kaposi’s sarcoma-associated herpesvirus (KSHV; human herpesvirus 8). KS is an AIDS-defining cancer, and it is changing in the post-antiretroviral therapy (post-ART) era.
Dirk P. Dittmer
doaj   +1 more source

Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections

Nature Communications, 2020
Disease prognosis after infection with Kaposi’s sarcoma-associated herpesvirus and Epstein-Barr Virus is highly variable. Here the authors carry out epidemiological and genetic analysis of a Ugandan cohort and suggest complex interactions may influence ...
Neneh Sallah, Wendell Miley, Nazzarena Labo, Tommy Carstensen, Segun Fatumo, Deepti Gurdasani, Martin O. Pollard, Alexander T. Dilthey, Alexander J. Mentzer, Vickie Marshall, Elena M. Cornejo Castro, Cristina Pomilla, Elizabeth H. Young, Gershim Asiki, Martin L. Hibberd, Manjinder Sandhu, Paul Kellam, Robert Newton, Denise Whitby, Inês Barroso   +19 more
doaj   +1 more source

Epigenetic Landscape of Kaposi's Sarcoma-Associated Herpesvirus Genome in Classic Kaposi's Sarcoma Tissues. [PDF]

PLoS Pathogens, 2017
Kaposi's sarcoma-associated herpesvirus (KSHV) is etiologically related to Kaposi's sarcoma (KS), primary effusion lymphoma (PEL) and multicentric Castleman's disease (MCD).
Rui Sun, Xiaohua Tan, Xing Wang, Xiaodong Wang, Lei Yang, Erle S Robertson, Ke Lan   +6 more
doaj   +1 more source

Modulation of immune system by Kaposi’s sarcoma-associated herpesvirus:Lessons from viral evasion strategies

Frontiers in Microbiology, 2012
Kaposi’s sarcoma-associated herpesvirus (KSHV), a member of the herpesvirus family, has evolved to establish a long-term, latent infection of cells such that while they carry the viral genome gene expression is highly restricted.
Hye-Ra eLee, Kevin eBrulois, LaiYee eWong, Jae U. eJung   +3 more
doaj   +1 more source

Productively infected murine Kaposi's sarcoma-like tumors define new animal models for studying and targeting KSHV oncogenesis and replication. [PDF]

PLoS ONE, 2014
Kaposi's sarcoma (KS) is an AIDS-defining cancer caused by the KS-associated herpesvirus (KSHV). KS tumors are composed of KSHV-infected spindle cells of vascular origin with aberrant neovascularization and erythrocyte extravasation. KSHV genes expressed
Brittany M Ashlock, Qi Ma, Biju Issac, Enrique A Mesri   +3 more
doaj   +1 more source

Virion Proteins of Kaposi's Sarcoma-Associated Herpesvirus [PDF]

Journal of Virology, 2005
ABSTRACT The proteins that compose a herpesvirus virion are thought to contain the functional information required for de novo infection, as well as virion assembly and egress. To investigate functional roles of Kaposi's sarcoma-associated herpesvirus (KSHV) virion proteins in viral productive replication and de novo infection, we attempted ...
Fan Xiu, Zhu, Jae Min, Chong, Lijun, Wu, Yan, Yuan   +3 more
openaire   +2 more sources

ORFeome-based arrays in eukaryotic expression vectors - a new approach to screen for the function of viral proteins [PDF]

, 2005
Since its first description in 1994 by Yuan Chang and Patrick Moore, Kaposi’s sarcoma-associated herpesvirus (KSHV) or Human Herpesvirus 8 (HHV-8) has emerged as a pathogen of international public health importance.
Roupelieva, Maria
core   +1 more source

Kaposi’s sarcoma in AIDS patients: a case series

Przegląd Dermatologiczny
Kaposi’s sarcoma is a multifocal tumor of endothelial origin associated with human herpesvirus 8 infection. Lesions typically appear as patches, plaques, or hemorrhagic nodules.
Małgorzata Dominiak, Julia Domurad-Falenta, Aleksandra Lesiak, Joanna Narbutt   +3 more
doaj   +1 more source

Long Non-Coding RNA and Epigenetic Gene Regulation of KSHV

Viruses, 2014
Kaposi’s sarcoma-associated herpesvirus (KSHV/human herpesvirus 8) is a γ-herpesvirus linked to Kaposi’s sarcoma (KS) and two lymphoproliferative disorders, primary effusion lymphoma (PEL or body-cavity B-lymphoma [BCBL]) and a subset of Multicentric ...
Mel Campbell, Hsing-Jien Kung, Yoshihiro Izumiya   +2 more
doaj   +1 more source

Kaposi’s Sarcoma-Associated Herpesvirus-Encoded circRNAs Are Expressed in Infected Tumor Tissues and Are Incorporated into Virions

mBio, 2020
Kaposi’s sarcoma-associated herpesvirus (KSHV) has recently been found to generate circular RNAs (circRNAs) from several KSHV genes, most abundantly from K10 (viral interferon regulatory factor 4 [vIRF4]), K7.3, and polyadenylated nuclear (PAN) RNA.
Bizunesh Abere, Jinghui Li, Hongzhao Zhou, Tuna Toptan, Patrick S. Moore, Yuan Chang   +5 more
doaj   +1 more source