Epigenetic Landscape of Kaposi's Sarcoma-Associated Herpesvirus Genome in Classic Kaposi's Sarcoma Tissues. [PDF]
PLoS Pathogens, 2017 Kaposi's sarcoma-associated herpesvirus (KSHV) is etiologically related to Kaposi's sarcoma (KS), primary effusion lymphoma (PEL) and multicentric Castleman's disease (MCD).
Rui Sun +6 more
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Modulation of Autophagy-Like Processes by Tumor Viruses [PDF]
, 2014 Autophagy is an intracellular degradation pathway for long-lived proteins and organelles. This process is activated above basal levels upon cell intrinsic or environmental stress and dysregulation of autophagy has been linked to various human diseases ...
Mack, Hildegard I. D., Munger, Karl
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Frontiers in Microbiology, 2012 Kaposi’s sarcoma-associated herpesvirus (KSHV), a member of the herpesvirus family, has evolved to establish a long-term, latent infection of cells such that while they carry the viral genome gene expression is highly restricted.
Hye-Ra eLee +3 more
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Productively infected murine Kaposi's sarcoma-like tumors define new animal models for studying and targeting KSHV oncogenesis and replication. [PDF]
PLoS ONE, 2014 Kaposi's sarcoma (KS) is an AIDS-defining cancer caused by the KS-associated herpesvirus (KSHV). KS tumors are composed of KSHV-infected spindle cells of vascular origin with aberrant neovascularization and erythrocyte extravasation. KSHV genes expressed
Brittany M Ashlock +3 more
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Raman tweezers provide the fingerprint of cells supporting the late stages of KSHV reactivation [PDF]
, 2009 Kaposi's sarcoma-associated herpesvirus (KSHV) has both latent and lytic phases of replication. The molecular switch that triggers a reactivation is still unclear. Cells from S phase of cell cycle provide apt conditions for an active reactivation.
Akula +56 more
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The T-Cell Immune Response against Kaposi's Sarcoma-Associated Herpesvirus
Advances in Virology, 2010 Kaposi's sarcoma-associated herpesvirus (KSHV) is the aetiological agent of Kaposi's sarcoma (KS), the most frequently arising malignancy in individuals with untreated HIV/AIDS.
Rebecca C. Robey +2 more
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Targeting the ATP-dependent formation of herpesvirus ribonucleoprotein particle assembly as an antiviral approach [PDF]
, 2016 Human herpesviruses are responsible for a range of debilitating acute and recurrent diseases, including a number of malignancies. Current treatments are limited to targeting the herpesvirus DNA polymerases, however with emerging viral resistance and ...
Foster, R +6 more
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For the Future Studies of Kaposi’s Sarcoma-Associated Herpesvirus [PDF]
Frontiers in Microbiology, 2012 It is 18 years since Kaposi’s sarcoma-associated virus (KSHV), also called human herpesvirus 8 (HHV-8), was found from Kaposis’ sarcoma (KS) by Chang et al. (1994). More than 8, 000 reports have been published so far and we have learned many things from this virus.
openaire +3 more sources
Kaposi’s sarcoma in AIDS patients: a case series
Przegląd DermatologicznyKaposi’s sarcoma is a multifocal tumor of endothelial origin associated with human herpesvirus 8 infection. Lesions typically appear as patches, plaques, or hemorrhagic nodules.
Małgorzata Dominiak +3 more
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Long Non-Coding RNA and Epigenetic Gene Regulation of KSHV
Viruses, 2014 Kaposi’s sarcoma-associated herpesvirus (KSHV/human herpesvirus 8) is a γ-herpesvirus linked to Kaposi’s sarcoma (KS) and two lymphoproliferative disorders, primary effusion lymphoma (PEL or body-cavity B-lymphoma [BCBL]) and a subset of Multicentric ...
Mel Campbell +2 more
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