Results 1 to 10 of about 26,579 (193)

Dendritic cells: Key players in human herpesvirus 8 infection and pathogenesis [PDF]

Frontiers in Microbiology, 2014
Human herpesvirus 8 (HHV-8; Kaposi’s sarcoma-associated herpesvirus) is an oncogenic gammaherpesvirus that primarily infects cells of the immune and vascular systems.
Diana M. Campbell, Giovanna eRappocciolo, Frank J. Jenkins, Frank J. Jenkins, Charles R. Rinaldo, Charles R. Rinaldo   +5 more
doaj   +3 more sources

Targeting Kaposi’s sarcoma associated herpesvirus encoded protease (ORF17) by a lysophosphatidic acid molecule for treating KSHV associated diseases

Frontiers in Cell and Developmental Biology, 2023
Kaposi’s sarcoma associated herpesvirus (KSHV) is causative agent of Kaposi’s sarcoma, Multicentric Castleman Disease and Pleural effusion lymphoma. KSHV-encoded ORF17 encodes a protease which cleaves -Ala-Ala-, -Ala-Ser- or -Ala-Thr-bonds.
Misbahuddin M Rafeeq, Alaa Hamed Habib, Alaa F. Nahhas, Najat Binothman, Majidah Aljadani, Jawaher Almulhim, Ziaullah M Sain, Mohammad Zubair Alam, Mohammad Zubair Alam, Norah A Alturki, Qamre Alam, Manish Manish, Rajnish Kumar Singh   +12 more
doaj   +1 more source

Mycosis fungoides and Kaposi’s sarcoma association in an HIV-negative patient [PDF]

Anais Brasileiros de Dermatologia, 2016
The association of mycosis fungoides and kaposi’s sarcoma in HIV-negative patients is a rare phenomenon. The presence of human herpesvirus 8 (HHV-8) – associated with all forms of Kaposi’s sarcoma – has also been recently identified in mycosis fungoides ...
Maria Carolina Prado Fleury Bariani, Luiz Fernando Fróes Fleury Júnior, Ana Maria Quinteiro Ribeiro, Siderley de Souza Carneiro, Tiago Arantes Pereira   +4 more
doaj   +1 more source

Kaposi’s sarcoma associated with chronic myeloid leukemia and imatinib mesylate therapy

Clinical Case Reports, 2022
Kaposi's sarcoma is associated with immunosuppression and human herpesvirus 8 infection, while rarely described in myeloid malignancies. Here, we illustrate a rare case of chronic myeloid leukemia treated with imatinib, a tyrosine kinase inhibitor, who ...
Matteo D’Addona, Luca Pezzullo, Valentina Giudice, Bianca Serio, Carlo Baldi, Pio Zeppa, Carmine Selleri   +6 more
doaj   +1 more source

Pulmonary Kaposi's sarcoma—an atypical clinical presentation

International Journal of Infectious Diseases, 2022
HIV-associated Kaposi's sarcoma is an angioproliferative neoplasia caused by infection with human herpesvirus 8. It typically presents with mucocutaneous involvement. Pulmonary Kaposi's sarcoma is rare, and an uncommon form of initial presentation of the
Ana Luísa Ramos, Joana Granado, Ana Isabel Calderón, Sandra André, Fernando Nogueira   +4 more
doaj   +1 more source

Kaposi's sarcoma-associated herpesvirus at 27

Tumour Virus Research, 2021
Kaposi's sarcoma-associated herpesvirus (KSHV) was discovered 27 years ago and its link to several pathologies – Kaposi's sarcoma, primary effusion lymphoma, and the B cell variant of Multicentric Castleman disease – is now well established.
Marta Maria Gaglia
doaj   +1 more source

Short communication: NKG2C+ NK cells contribute to increases in CD16+CD56- cells in HIV type 1+ individuals with high plasma viral load. [PDF]

, 2012
Chronic HIV-1 infection results in the expansion of both NKG2C+ and CD16+CD56- human natural killer cells. NKG2C+ cells proliferate in response to human cytomegalovirus (HCMV) and expansion of the dysfunctional CD56-CD16+ natural killer (NK) cells is ...
Bower, Mark, Gazzard, Brian G, Goodier, Martin R, Gregson, John NS, Kuri-Cervantes, Leticia, Mela, Christopher M   +5 more
core   +1 more source

Multiple human herpesvirus-8 infection [PDF]

, 2003
In Malawian patients with Kaposi sarcoma (KS) and their relatives, we investigated nucleotide-sequence variation in human herpesvirus-8 (HHV-8) subgenomic DNA, amplified from oral and blood samples by use of polymerase chain reaction.
Beyari, MM, Cook, RD, Hodgson, TA, Kondowe, W, Molyneux, EM, Porter, SR, Scully, CM, Teo, CG   +7 more
core   +1 more source

The activation of KSHV lytic cycle blocks autophagy in PEL cells [PDF]

, 2015
This study confirms that autophagy is activated concomitantly with KSHV lytic cycle induction, and that autophagy inhibition by BECN1 knockdown reduces viral lytic gene expression.
CIRONE, Mara, FAGGIONI, Alberto, FARINA, Antonella, Filardi, M, GONNELLA, ROBERTA, GRANATO, Marisa, SANTARELLI, Roberta, TORRISI, Maria Rosaria   +7 more
core   +1 more source

Kaposi’s Sarcoma-associated Herpesvirus

Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2016
Background: Kaposi’s sarcoma (KS) revealed by Moritz Kaposi first time in 1872. In the early 1980, the prevalence of SK began to increase dramatically.
Novia Indriyani Adisty, Sawitri Sawitri, Willy Sandhika   +2 more
doaj   +1 more source