Results 31 to 40 of about 26,618 (232)

Recent advances in understanding Kaposi’s sarcoma-associated herpesvirus [version 1; referees: 2 approved]

open access: yesF1000Research, 2016
Kaposi’s sarcoma (KS)-associated herpesvirus (KSHV) is an oncogenic human herpesvirus. KSHV is associated with three cancers in the human population: KS, primary effusion lymphoma (PEL), and multicentric Castleman’s disease (MCD). KS is the leading cause
Nathan J. Dissinger, Blossom Damania
doaj   +1 more source

Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections

open access: yesNature Communications, 2020
Disease prognosis after infection with Kaposi’s sarcoma-associated herpesvirus and Epstein-Barr Virus is highly variable. Here the authors carry out epidemiological and genetic analysis of a Ugandan cohort and suggest complex interactions may influence ...
Neneh Sallah   +19 more
doaj   +1 more source

Productively infected murine Kaposi's sarcoma-like tumors define new animal models for studying and targeting KSHV oncogenesis and replication. [PDF]

open access: yesPLoS ONE, 2014
Kaposi's sarcoma (KS) is an AIDS-defining cancer caused by the KS-associated herpesvirus (KSHV). KS tumors are composed of KSHV-infected spindle cells of vascular origin with aberrant neovascularization and erythrocyte extravasation. KSHV genes expressed
Brittany M Ashlock   +3 more
doaj   +1 more source

Restricted Kaposi’s Sarcoma (KS) Herpesvirus Transcription in KS Lesions from Patients on Successful Antiretroviral Therapy

open access: yesmBio, 2011
Kaposi’s sarcoma (KS) is caused by Kaposi’s sarcoma-associated herpesvirus (KSHV; human herpesvirus 8). KS is an AIDS-defining cancer, and it is changing in the post-antiretroviral therapy (post-ART) era.
Dirk P. Dittmer
doaj   +1 more source

Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy [PDF]

open access: yes, 2017
KSHV and EBV are gammaherpesviruses strictly linked to human cancers. Even if the majority of cancer cells harbor a latent infection, the few cells that undergo viral replication may contribute to the pathogenesis and maintenance of the virus-associated ...
Cirone, Mara   +7 more
core   +2 more sources

Modulation of immune system by Kaposi’s sarcoma-associated herpesvirus:Lessons from viral evasion strategies

open access: yesFrontiers in Microbiology, 2012
Kaposi’s sarcoma-associated herpesvirus (KSHV), a member of the herpesvirus family, has evolved to establish a long-term, latent infection of cells such that while they carry the viral genome gene expression is highly restricted.
Hye-Ra eLee   +3 more
doaj   +1 more source

Reactivation and Lytic Replication of Kaposi’s Sarcoma-Associated Herpesvirus: An Update

open access: yesFrontiers in Microbiology, 2017
The life cycle of Kaposi’s sarcoma-associated herpesvirus (KSHV) consists of two phases, latent and lytic. The virus establishes latency as a strategy for avoiding host immune surveillance and fusing symbiotically with the host for lifetime persistent ...
K. Aneja, Yan Yuan
semanticscholar   +1 more source

The T-Cell Immune Response against Kaposi's Sarcoma-Associated Herpesvirus

open access: yesAdvances in Virology, 2010
Kaposi's sarcoma-associated herpesvirus (KSHV) is the aetiological agent of Kaposi's sarcoma (KS), the most frequently arising malignancy in individuals with untreated HIV/AIDS.
Rebecca C. Robey   +2 more
doaj   +1 more source

Long Non-Coding RNA and Epigenetic Gene Regulation of KSHV

open access: yesViruses, 2014
Kaposi’s sarcoma-associated herpesvirus (KSHV/human herpesvirus 8) is a γ-herpesvirus linked to Kaposi’s sarcoma (KS) and two lymphoproliferative disorders, primary effusion lymphoma (PEL or body-cavity B-lymphoma [BCBL]) and a subset of Multicentric ...
Mel Campbell   +2 more
doaj   +1 more source

Pseudomonas aeruginosa Stimulates Inflammation and Enhances Kaposi’s Sarcoma Herpesvirus-Induced Cell Proliferation and Cellular Transformation through both Lipopolysaccharide and Flagellin

open access: yesmBio, 2020
Inflammation triggered by innate immunity promotes carcinogenesis in cancer. Kaposi’s sarcoma (KS), a hyperproliferative and inflammatory tumor caused by Kaposi’s sarcoma-associated herpesvirus (KSHV) infection, is the most common cancer in AIDS patients.
Ashley Markazi   +3 more
doaj   +1 more source

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