Results 81 to 90 of about 26,618 (232)
DNA-Packing Portal and Capsid-Associated Tegument Complexes in the Tumor Herpesvirus KSHV. [PDF]
, 2019 Assembly of Kaposi's sarcoma-associated herpesvirus (KSHV) begins at a bacteriophage-like portal complex that nucleates formation of an icosahedral capsid with capsid-associated tegument complexes (CATCs) and facilitates translocation of an ∼150-kb dsDNA
Bi, Guo-Qiang +6 more
core +1 more source
JEADV Clinical Practice, Volume 5, Issue 1, Page 226-230, March 2026.Capsule summary We report a case of non‐epidemic Kaposi sarcoma in an immunocompetent HIV‐negative man who has sex with men, presenting with localized cutaneous lesions on the foot. Multiple laser modalities—including CO2, PDL, KTP, and combined PDL/Nd:YAG—failed to achieve meaningful clinical improvement, and disease progression continued with new ...
M. Sin‐Soler +5 more
wiley +1 more source
Kaposi's sarcoma-associated herpesvirus open reading frame 50 represses p53-induced transcriptional activity and apoptosis [PDF]
, 2001 Kaposi's sarcoma-associated herpesvirus (KSHV) open reading frame 50 (ORF50) encodes a viral transcriptional activator which stimulates the transcription of viral early and late genes of KSHV.
Gwack, YOUSANG +6 more
core +1 more source
Protein Lactylation in Cancer: Mechanisms and Therapeutic Targets
MedComm, Volume 7, Issue 3, March 2026.This schematic illustrates the central role of lactylation, a lactate‐derived posttranslational modification, in linking metabolic reprogramming to cancer progression and therapy resistance. At its core, lactylation modulates proteins, influenced by metabolic shifts and environmental factors.
Qianying Ouyang +10 more
wiley +1 more source
Seroprevalence of human herpesvirus 8 infection in children born to HIV-1- infected women in São Paulo, Brazil [PDF]
, 2005 Human herpesvirus-8 (HHV-8) appears to be transmitted mainly by sexual contact. However, several studies suggest that in developing countries the infection may be acquired early in life by routes other than sexual transmission.
De Moraes-Pinto, Maria Isabel +5 more
core +2 more sources
MedComm – Oncology, Volume 5, Issue 1, March 2026.Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang +7 more
wiley +1 more source
KSHV-Mediated Angiogenesis in Tumor Progression
Viruses, 2016 Human herpesvirus 8 (HHV-8), also known as Kaposi’s sarcoma-associated herpesvirus (KSHV), is a malignant human oncovirus belonging to the gamma herpesvirus family. HHV-8 is closely linked to the pathogenesis of Kaposi’s sarcoma (KS) and two other B-cell
Pravinkumar Purushothaman +3 more
doaj +1 more source
Protein chainmail variants in dsDNA viruses. [PDF]
, 2015 First discovered in bacteriophage HK97, biological chainmail is a highly stable system formed by concatenated protein rings. Each subunit of the ring contains the HK97-like fold, which is characterized by its submarine-like shape with a 5-stranded β ...
Chiou, Joshua, Zhou, Z Hong
core +2 more sources
Reviews in Medical Virology, Volume 36, Issue 2, March 2026.ABSTRACT Idiopathic pulmonary fibrosis (IPF) is a serious progressive complication of the respiratory system, which is profoundly associated with persistent extracellular matrix (ECM) deposition, fibrosis, and disrupted tissue regeneration. Emerging evidence shows that epithelial–mesenchymal transition (EMT) acts as a key factor in the pathogenesis of ...
Ningzi Zang +9 more
wiley +1 more source
Viruses, 2015 Kaposi’s sarcoma associated herpesvirus (KSHV) is the etiologic agent of Kaposi’s sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman’s disease (MCD).
Jungang Chen +3 more
doaj +1 more source