Results 41 to 50 of about 1,120 (144)

CT features of generalized lymphangiomatosis in adult patients

, 2021
Objective: The objective was to present computed tomographic (CT) findings of generalized lymphangiomatosis in young adults that was at first misdiagnosed with malignancy. Materials and methods: We reviewed the clinical and radiological findings of three
심성신, 김유경, 장중현, 김관창   +3 more
core   +1 more source

Kaposiform hemangioendothelioma in tonsil of a child associated with cervical lymphangioma: a rare case report

World Journal of Surgical Oncology, 2011
Kaposiform hemangioendothelioma (KHE) is an uncommon vascular tumor of intermediate malignant potential, usually occurs in the extremities and retroperitoneum of infants and is characterized by its association with lymphangiomatosis and Kasabach-Merritt ...
Kulkarni Suyash S, Sethi Shweta, Rekhi Bharat, Jambhekar Nirmala A   +3 more
doaj   +1 more source

Changes in cell morphology and function induced by the NRAS Q61R mutation in lymphatic endothelial cells.

PLoS ONE
Recently, a low-level somatic mutation in the NRAS gene (c.182 A > G, Q61R) was identified in various specimens from patients with kaposiform lymphangiomatosis.
Shiho Yasue, Michio Ozeki, Akifumi Nozawa, Saori Endo, Hidenori Ohnishi   +4 more
doaj   +1 more source

Lymphangiomatosis of the ileum with perforation: A case report and review of the literature [PDF]

, 2019
Lymphangiomatosis is a benign proliferation of lymph vessels. Lymphatic diseases can vary from small lymphangioma to generalized lymphangiomatosis, which is a rare condition and can have several clinical manifestations.
Carlei F., Muolo C., Giuliani A., Walid A Fatayer M., Calvisi G., Maffione F., Schietroma M., Romano L., Coletti G., Vicentini V.   +9 more
core   +1 more source

Systemic congenital lymphangiomatosis [PDF]

, 1996
Systemic lymphangiomatosis is a rare disease characterized by the exageration of lymphatic channel proliferation, occurring in children and young adults.
Ligia Maria Suppo de Souza, Maria Regina Bentlin, Eliana Souto de Abreu, Carlos Eduardo Bacchi   +3 more
core   +2 more sources

The impact of sirolimus therapy on lesion size, clinical symptoms, and quality of life of patients with lymphatic anomalies

Orphanet Journal of Rare Diseases, 2019
Background Lymphatic anomalies (LAs) include several disorders in which abnormal lymphatic tissue invades the neck, chest, and various organs. Progressive cases may result in lethal outcomes and have proven difficult to treat.
Michio Ozeki, Akifumi Nozawa, Shiho Yasue, Saori Endo, Ryuta Asada, Hiroya Hashimoto, Toshiyuki Fukao   +6 more
doaj   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Percutaneous osteoplasty in treatment of bone lymphangiomatosis [PDF]

, 2013
Primary bone lymphangiomatosis is a disease of unknown etiology that can cause lytic lesions in long bones, the pelvis, the spinal column and the cranium. We are presenting the case of a woman with localized bone lymphangiomatosis in the left knee.
Mifsut Miedes, Damian, Saravia, Marcos, Gomar Sancho, Francisco, Renovell Ferrer, Pablo, Gomar, Francisco, Renovell, Pablo   +5 more
core   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Targeted Therapies in Infantile Hemangiomas and Vascular Malformations: From β‐Blockers to PI3K/AKT/mTOR Inhibitors

Journal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.
ABSTRACT Vascular tumours and malformations encompass infantile hemangiomas (IHs) and genetically driven vascular malformations with distinct natural histories and therapeutic vulnerabilities. The discovery that the non‐selective beta‐blocker propranolol induces rapid regression of proliferating IHs established the first widely adopted systemic ...
Hubert Arasiewicz, Michal Dec
wiley   +1 more source