Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion
Advanced Science, EarlyView.The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li +10 more
wiley +1 more source
High Concordance of Self-Reported and Objective Measures of Antihypertensive Use in Individuals Living with HIV in a Resource-Limited Setting. [PDF]
Glob HeartJere J +8 more
europepmc +1 more source
The $\lambda$–$\kappa$–$\mu$ Fading Distribution
IEEE Antennas and Wireless Propagation LettersHuan Wang +5 more
openaire +1 more source
Hierarchical Artificial Muscle with Nonlinear Elasticity for Antagonistic and Cyclic Robotics
Advanced Science, EarlyView.We construct hierarchical muscles by plying nylon fibers around a heating wire. The hierarchical muscle shows a J‐shaped passive curve, which shows benefit in antagonistic muscle pair and work accumulation mechanism. We also develop a computational, first‐principle model to understand the physics of both active actuation stroke and passive J‐curve ...
Samuel Tsai +15 more
wiley +1 more source
Evaluation of pre-operative endometrial biopsy accuracy and etiological distribution in abnormal uterine bleeding using the PALM-COEIN classification. [PDF]
Front Med (Lausanne)Deniz R +11 more
europepmc +1 more source
Unveiling a Bulk WTaV Multicomponent Alloy With Superior Thermal Properties and Manufacturability
Advanced Science, EarlyView.ABSTRACT Many tungsten (W)‐based medium and high entropy alloys (HEA) demonstrate superior microstructural stability and enhanced mechanical properties as compared to pure W, effectively rendering them as viable candidate materials for extreme environments such as nuclear fusion, aerospace applications, and so on.
Ishtiaque K. Robin +11 more
wiley +1 more source
Capsule Endoscopy-Guided Diagnosis of Small Bowel Lymphoma Presenting as Protein-Losing Enteropathy: Complementary Role of Peripheral Blood Flow Cytometry. [PDF]
Diagnostics (Basel)Abdulrasak M, Axler O, Kapás B, Toth E.
europepmc +1 more source
Modulation of electron-acoustic waves in a plasma with kappa distribution
, 2016 Hilmi Demı́ray
openalex +2 more sources
Advanced Science, EarlyView.A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park +11 more
wiley +1 more source