Results 31 to 40 of about 29,707 (250)

KAPPA: A Package for the Synthesis of Optically Thin Spectra for the Non-Maxwellian κ-Distributions. III. Improvements to Ionization Equilibrium and Extension to κ < 2

The Astrophysical Journal Supplement Series, 2023
The KAPPA package is designed for calculations of optically thin spectra for the non-Maxwellian κ -distributions. This paper presents an extension of the database to allow calculations of the spectra for extreme values of κ < 2, which are important for ...
Elena Dzifčáková, Jaroslav Dudík, Martina Pavelková, Božena Solarová, Alena Zemanová   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Ionization equilibrium of nitrogen under kappa electron distributions

Astronomy & Astrophysics
Non-Maxwellian electron energy distributions, such as kappa distributions, have been proposed to explain discrepancies in observed astrophysical plasmas. We employed the coronal approximation to study the level populations of ionized nitrogen under kappa
Song Yunliang, Li Bowen, Chen Ximeng
doaj   +1 more source

Universality of kappa distributions

Europhysics Letters
Abstract This paper reveals the universality of the particle energy distribution function, despite the arbitrariness that characterizes the generalized thermodynamic entropic function. We show that the canonical distribution, that is, the distribution function that maximizes this entropy under the constraints of canonical ensemble, is ...
George Livadiotis, David J. McComas
openaire   +1 more source

The kappa parameter and kappa-distribution in kappa-deformed statistics for the systems in an external field

, 2006
8 pages, 16 references.
Guo, Lina, Du, Jiulin
openaire   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

The theory of thermodynamic relativity

Scientific Reports
We introduce the theory of thermodynamic relativity, a unified theoretical framework for describing both entropies and velocities, and their respective physical disciplines of thermodynamics and kinematics, which share a surprisingly identical ...
George Livadiotis, David J. McComas
doaj   +1 more source