Results 151 to 160 of about 1,463,708 (228)

Effects of Biased Analogues of the Kappa Opioid Receptor Agonist, U50,488, in Preclinical Models of Pain and Side Effects. [PDF]

Molecules
van de Wetering R, Vu LY, Kornberger LD, Luo D, Scouller B, Hong S, Paton K, Prisinzano TE, Kivell BM.   +8 more
europepmc   +1 more source

Pharmacological characterization of the novel selective kappa opioid receptor agonists 10-Iodo-Akuammicine and 10-Bromo-akuammicine in mice. [PDF]

Neuropharmacology
Bland K, Chen C, Huang P, Ho C, Howe T, Ocampo K, Zhao P, Creed S, Noel-Torres J, Riley AP, Liu-Chen LY.   +10 more
europepmc   +1 more source

A New Trick of Old Dogs: Can Kappa Opioid Receptor Antagonist Properties of Antidepressants Assist in Treating Treatment-Resistant Depression (TRD)? [PDF]

Pharmaceuticals (Basel)
Schreiber S, Keidan L, Pick CG.
europepmc   +1 more source

Navacaprant, a Novel and Highly Selective Kappa Opioid Receptor Antagonist, in Adults With Major Depressive Disorder: A Randomized, Double-Blind Phase 2 Clinical Trial. [PDF]

J Clin Psychopharmacol
Mathew SJ, Cutler AJ, Visitacion NC, Gold M, Yuan J, Aurora B.   +5 more
europepmc   +1 more source

Effects of the kappa-opioid receptor antagonist nor-binaltorphimine on methamphetamine-vs-food choice in male rhesus monkeys. [PDF]

Drug Alcohol Depend
Banks ML, Rice KC.
europepmc   +1 more source

A Bicyclic Analog of the Linear Peptide Arodyn Is a Potent and Selective Kappa Opioid Receptor Antagonist. [PDF]

Molecules
Gisemba SA, Ferracane MJ, Murray TF, Aldrich JV.   +3 more
europepmc   +1 more source

Deletion of β-arrestin 2 in mice affects kappa opioid receptor-mediated behaviors depending on sex, ovariectomy status, and behavioral endpoints. [PDF]

Neurosci Lett
Huang P, Ho CK, Bland K, Liu-Chen LY.
europepmc   +1 more source

Impact of renal impairment on the pharmacokinetic profile of intravenous difelikefalin, a kappa opioid receptor agonist for the treatment of pruritus. [PDF]

BMC Nephrol
Spencer RH, Noonan PK, Marbury T, Menzaghi F.   +3 more
europepmc   +1 more source

Activation of G protein gated inwardly rectifying potassium (GIRK) channels in keratinocytes mediates peripheral kappa opioid receptor-mediated antinociception. [PDF]

Neuropharmacology
Pando MM, Debner EK, Jacobs BA, Jamshidi RJ, Jennings EM, Clarke WP, Berg KA.   +6 more
europepmc   +1 more source

Discovery of Novel, Selective, and Nonbasic Agonists for the Kappa-Opioid Receptor Determined by Salvinorin A-Based Virtual Screening. [PDF]

J Med Chem
Puls K, Olivé-Marti AL, Hongnak S, Lamp D, Spetea M, Wolber G.   +5 more
europepmc   +1 more source