Results 201 to 210 of about 71,106 (270)

Docking 14 million virtual isoquinuclidines against the mu and kappa opioid receptors reveals dual antagonists-inverse agonists with reduced withdrawal effects

Seth F. Vigneron, Shohei Ohno, João Braz, Joseph Kim, Oh Sang Kweon, Chase M. Webb, Christian B. Billesbølle, Karnika Bhardwaj, John J. Irwin, Aashish Manglik, Allan I. Basbaum, Jonathan A. Ellman, Brian K. Shoichet   +12 more
openalex   +1 more source

Distinct Mu, Delta, and Kappa Opioid Receptor Mechanisms Underlie Low Sociability and Depressive-Like Behaviors During Heroin Abstinence

Neuropsychopharmacology, 2014
Pierre-Eric Lutz, Gülebru Ayranci, Paul Chu-Sin-Chung, A. Matifas, P. Koebel, D. Filliol, K. Befort, A. Ouagazzal, B. Kieffer   +8 more
semanticscholar   +1 more source

Kappa-opioid receptor stimulation in the nucleus accumbens shell and ethanol drinking: Differential effects by rostro-caudal location and level of drinking. [PDF]

Neuropsychopharmacology
Pirino BE, Hawks A, Carpenter BA, Candelas PG, Gargiulo AT, Curtis GR, Karkhanis AN, Barson JR.   +7 more
europepmc   +1 more source

Co-targeting the kappa opioid receptor and dopamine transporter reduces motivation to self-administer cocaine and partially reverses dopamine system dysregulation. [PDF]

Sci Rep
Estave PM, Albertson SE, Karkhanis AN, Jones SR.   +3 more
europepmc   +1 more source

A Combination of a Dopamine Receptor 2 Agonist and a Kappa Opioid Receptor Antagonist Synergistically Reduces Weight in Diet-Induced Obese Rodents. [PDF]

Nutrients
Cicuéndez B, Pérez-García J, Folgueira C.   +2 more
europepmc   +1 more source

Effects ofmuandkappaopioid receptor agonists and antagonists on contraction of isolated colon strips of rats with cathartic colon

, 2004
Baohua Liu
openalex   +2 more sources

Design and Synthesis of a Novel and Selective Kappa Opioid Receptor (KOR) Antagonist (BTRX-335140)

, 2019
Miguel Guerrero, Mariangela Urbano, Eun-Kyong Kim, Ana M. Gamo, Sean Riley, Lusine Abgaryan, Nora B. Leaf, Lori Jean Van Orden, Steven J Brown, Jennifer Y. Xie, Frank Porreca, Michael D. Cameron, Hugh Rosen, Edward Roberts   +13 more
openalex   +2 more sources

Genetic Analysis of Mu and Kappa Opioid Receptor and COMT Enzyme in Cancer Pain Tunisian Patients Under Opioid Treatment.

, 2017
Imen Chatti, Jean‐Baptiste Woillard, A. Mili, Isabelle Creveaux, Ilhem Ben Charfeddine, J. Feki, Sarah Langlais, Leïla Ben Fatma, Ali Saâd, Moez Gribaa, Fréderic Libert   +10 more
openalex   +1 more source

Sex Differences in the Effects of a Kappa Opioid Receptor Antagonist in the Forced Swim Test

, 2018
Abigail Laman-Maharg, Alexia V. Williams, Mikaela D. Zufelt, Vanessa A. Minie, Stephanie Ramos-Maciel, Rebecca Hao, Evelyn Ordoñes Sanchez, Tiffany Copeland, Jill L. Silverman, Angelina Leigh, Rodney W. Snyder, F. Ivy Carroll, Timothy R. Fennell, Brian C. Trainor   +13 more
openalex   +1 more source

A randomized, double‐blind, placebo‐controlled study of the kappa opioid receptor antagonist, CERC‐501, in a human laboratory model of smoking behavior

, 2019
Jermaine D. Jones, Shanna Babalonis, Ronald N. Marcus, Bradley Vince, Debra Kelsh, Michelle R. Lofwall, Heather Fraser, Blake Paterson, Suky Martinez, Diana Martínez, Edward V. Nunes, Sharon Walsh, Sandra D. Comer   +12 more
openalex   +2 more sources