Results 141 to 150 of about 6,232 (184)
KASH 'n Karry: The KASH domain family of cargo-specific cytoskeletal adaptor proteins
BioEssays, 2005 AbstractA diverse family of proteins has been discovered with a small C‐terminal KASH domain in common. KASH domain proteins are localized uniquely to the outer nuclear envelope, enabling their cytoplasmic extensions to tether the nucleus to actin filaments or microtubules. KASH domains are targeted to the outer nuclear envelope by SUN domains of inner
Daniel Starr
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Current Biology, 2011 What are KASH proteins? KASH proteins (Klarsicht, ANC-1, Syne homology) are C-tail-anchored membrane proteins, which are targeted specifically to the outer membrane of the nuclear envelope. The defining feature of KASH proteins is the carboxy-terminal KASH domain that consists of a hydrophobic region spanning the outer nuclear membrane and 6–30 ...
Daniel Starr
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How plants LINC the SUN to KASH [PDF]
Nucleus, 2013 Linkers of the nucleoskeleton to the cytoskeleton (LINC) complexes formed by SUN and KASH proteins are conserved eukaryotic protein complexes that bridge the nuclear envelope (NE) via protein-protein interactions in the NE lumen. Revealed by opisthokont studies, LINC complexes are key players in multiple cellular processes, such as nuclear and ...
Iris Meier
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KASHing up with the nucleus: novel functional roles of KASH proteins at the cytoplasmic surface of the nucleus [PDF]
Current Opinion in Cell Biology, 2014 Nuclear-cytoskeletal connections are central to fundamental cellular processes, including nuclear positioning and chromosome movements in meiosis. The cytoskeleton is coupled to the nucleoskeleton through conserved KASH-SUN bridges, or LINC complexes, that span the nuclear envelope.
Daniel Starr, Gw Gant Luxton
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Making the LINC: SUN and KASH protein interactions [PDF]
Biological Chemistry, 2015 AbstractCell nuclei are physically integrated with the cytoskeleton through the linker of nucleoskeleton and cytoskeleton (LINC) complex, a structure that spans the nuclear envelope to link the nucleoskeleton and cytoskeleton. Outer nuclear membrane KASH domain proteins and inner nuclear membrane SUN domain proteins interact to form the core of the ...
Kyle Roux, Birendra Kc
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Proceedings of the 3rd International Conference on Communication and Information Processing, 2017
Game can offer a variety of benefits in learning. There are two ways that a user can learn via game, it's either through gamification or mobile learning based game. This paper covered both. This study was created in a foundation that everyone deserve to be financially literate.
Mary Jane C. Samonte +3 more
openaire +1 more source
Game can offer a variety of benefits in learning. There are two ways that a user can learn via game, it's either through gamification or mobile learning based game. This paper covered both. This study was created in a foundation that everyone deserve to be financially literate.
Mary Jane C. Samonte +3 more
openaire +1 more source
Purification and Structural Analysis of SUN and KASH Domain Proteins [PDF]
Methods in Enzymology, 2016 Molecular tethers span the nuclear envelope to mechanically connect the cytoskeleton and nucleoskeleton. These bridge-like tethers, termed linkers of nucleoskeleton and cytoskeleton (LINC) complexes, consist of SUN proteins at the inner nuclear membrane and KASH proteins at the outer nuclear membrane.
Thomas U Schwartz +2 more
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Structural insights into SUN-KASH complexes across the nuclear envelope [PDF]
Cell Research, 2012 Linker of the nucleoskeleton and the cytoskeleton (LINC) complexes are composed of SUN and KASH domain-containing proteins and bridge the inner and outer membranes of the nuclear envelope. LINC complexes play critical roles in nuclear positioning, cell polarization and cellular stiffness. Previously, we reported the homotrimeric structure of human SUN2.
Qiang Wang, Zhaocai Zhou, Zhubing Shi
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2006
In recent years the computer algebra system KASH/KANT for number theory has evolved considerably. We present its new features and introduce the related components, QaoS (Querying Algebraic Objects System) and GiANT (Graphical Algebraic Number Theory).
Sebastian Freundt +3 more
openaire +1 more source
In recent years the computer algebra system KASH/KANT for number theory has evolved considerably. We present its new features and introduce the related components, QaoS (Querying Algebraic Objects System) and GiANT (Graphical Algebraic Number Theory).
Sebastian Freundt +3 more
openaire +1 more source