Results 61 to 70 of about 6,232 (184)

Identification of nuclear membrane SUN proteins and components associated with wheat fungal stress responses

open access: yesStress Biology
In eukaryotes, the nuclear membrane that encapsulates genomic DNA is composed of an inner nuclear membrane (INM), an outer nuclear membrane (ONM), and a perinuclear space.
Huan Guo   +11 more
doaj   +1 more source

Interesting Case of Lung Fibrosis in a Patient With Vascular Ehlers Danlos Syndrome

open access: yesRespirology Case Reports, Volume 14, Issue 6, June 2026.
We present the case of a 39‐year‐old man with recurrent spontaneous (including bilateral) pneumothoraces and haemoptysis who had unusual thoracic computed tomography (CT) abnormalities. In the absence of typical phenotypic features, these radiological findings prompted genetic testing, which confirmed a pathogenic COL3A1 mutation and established the ...
Alicia Su Huey Kwan   +3 more
wiley   +1 more source

The kinesin AtPSS1 promotes synapsis and is required for proper crossover distribution in meiosis.

open access: yesPLoS Genetics, 2014
Meiotic crossovers (COs) shape genetic diversity by mixing homologous chromosomes at each generation. CO distribution is a highly regulated process. CO assurance forces the occurrence of at least one obligatory CO per chromosome pair, CO homeostasis ...
Yann Duroc   +9 more
doaj   +1 more source

Glutamate plasticity woven through the progression to alcohol use disorder: a multi-circuit perspective [version 1; referees: 2 approved]

open access: yesF1000Research, 2017
Glutamate signaling in the brain is one of the most studied targets in the alcohol research field. Here, we report the current understanding of how the excitatory neurotransmitter glutamate, its receptors, and its transporters are involved in low ...
Lara Hwa, Joyce Besheer, Thomas Kash
doaj   +1 more source

Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes

open access: yesAdvanced Science, Volume 13, Issue 30, 28 May 2026.
This work develops dynamically softening polyacrylamide hydrogels for time‐resolved imaging during continuous mechanical transitions. The study revealed that mechanotransduction is biphasic; YAP/TAZ inactivation is driven by early loss of the nucleocytoskeletal continuum connecting subnuclear adhesions, F‐actin, and the nuclear envelope, coupled with ...
Alessandro Gandin   +12 more
wiley   +1 more source

Nuclear Mechanotransduction Across the Metastatic Cascade: Decoding Spatiotemporal Heterogeneity in Cancer Dissemination

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
Tumor metastasis results from complex interactions between cancer cells and mechanical microenvironments. We propose a “nucleus‐centered, cross‐stage mechanical signal decoding” model, highlighting how nuclear mechanosensors interpret forces at different stages.
Linqi Song   +4 more
wiley   +1 more source

Structural and Compositional Characteristics of Technical Lignin Derived From Non-Wood Biomass: Bagasse and Kash

open access: yesAdvances in Polymer Technology
Lignin is one of the available biopolymers on earth, so it can play a vital role in moving toward a bio-based society. In this paper, lignin derived from non-wood sources like bagasse and kash was characterized in order to facilitate its valorization ...
Md Nur Alam Likhon   +4 more
doaj   +1 more source

Predictive value of seizure onset for gross motor dysfunction in individuals with pathogenic GABRB2 and GABRB3 variants

open access: yesEpilepsia, Volume 67, Issue 4, Page 1945-1960, April 2026.
Abstract Objective Pathogenic variants in γ‐aminobutyric acid type A (GABAA) receptor genes have been associated with a wide spectrum of neurological disorders. We aimed to delineate the clinical trajectories associated with gain‐of‐function (GoF) and loss‐of‐function (LoF) variants in GABRB2 and GABRB3, and to develop a risk‐prediction model for gross
Sebastian Ortiz   +73 more
wiley   +1 more source

Developing a KASH Model as a Training Strategy: A Qualitative Approach

open access: yes, 2023
The objective is to enhance an understanding of how the KASH model can be used as a training tool to help managers achieve their goals of increasing individual commitment and organizational effectiveness. This study employed a qualitative method using a semi-structured interview to examine the application of the KASH model in Malaysia’s automotive ...
Vasudevan, Hemaloshinee   +5 more
openaire   +2 more sources

Leptotene/zygotene chromosome movement via the SUN/KASH protein bridge in Caenorhabditis elegans.

open access: yesPLoS Genetics, 2010
The Caenorhabditis elegans inner nuclear envelope protein matefin/SUN-1 plays a conserved, pivotal role in the process of genome haploidization.
Antoine Baudrimont   +10 more
doaj   +1 more source

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