Results 11 to 20 of about 1,185 (155)
16S rRNA methyltransferase KsgA contributes to oxidative stress and antibiotic resistance in Pseudomonas aeruginosa [PDF]
Scientific ReportsRibosomal RNA (rRNA) modifications are involved in multiple biological processes. KsgA is a 16S rRNA adenine dimethyltransferase that methylates at the adenines 1518 and 1519 (A1518/1519) positions, which are located near the ribosome decoding center ...
Kamonwan Phatinuwat +4 more
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Discovery of Kasugamycin as a Potent Inhibitor of Glycoside Hydrolase Family 18 Chitinases
Frontiers in Molecular Biosciences, 2021 Kasugamycin, a well-known aminoglycoside antibiotic, has been used widely in agriculture and medicine to combat microbial pathogens by binding the ribosome to inhibit translation.
Huitang Qi +6 more
doaj +1 more source
Host chitinase 3-like-1 is a universal therapeutic target for SARS-CoV-2 viral variants in COVID-19
eLife, 2022 Coronavirus disease 2019 (COVID-19) is the disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2; SC2), which has caused a worldwide pandemic with striking morbidity and mortality. Evaluation of SC2 strains demonstrated impressive
Suchitra Kamle +6 more
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Antibiotics in Crop Production
EDIS, 2020 This new 5-page article presents an overview of the use of antibiotics in agriculture. Several of the most severe bacterial diseases of tree fruit and other crops are discussed and their integrated management, which includes the use of antibiotics, is ...
Leigh Archer +2 more
doaj +5 more sources
Assembling Hexahedral Supramolecular Nano-Aggregates on Rice Wax Layer Matrices to Promote the Leaf Deposition and Bioavailability of Bactericides for Plant Protections. [PDF]
Adv Sci (Weinh)To address the problem of off‐target movement and low bioavailability of pesticides, two anisotropic supramolecular building units (BiTA18@β‐CD and BiTA18@γ‐CD) have been invented that can self‐assemble into nano‐sized hexagonal cuboids on the rice microcrystalline matrix. This manipulation realizes the enhanced utilization of bactericides for rice and
Yang R, Yang J, Liu M, Liu J, Wang P.
europepmc +2 more sources
Nanomaterials, 2022 Multimodal antimicrobial technology is regarded as a promising strategy for controlling plant diseases because it enhances antimicrobial efficacy by blocking multiple pesticide-resistance pathways.
You Liang +9 more
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A Chemical-Genomic Screen of Neglected Antibiotics Reveals Illicit Transport of Kasugamycin and Blasticidin S. [PDF]
PLoS Genetics, 2016 Fighting antibiotic resistance requires a deeper understanding of the genetic factors that determine the antibiotic susceptibility of bacteria. Here we describe a chemical-genomic screen in Escherichia coli K-12 that was designed to discover new aspects ...
Anthony L Shiver +6 more
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Biomedicines, 2022 Kasugamycin (KSM), an aminoglycoside antibiotic, is composed of three chemical moieties: D-chiro-inositol, kasugamine and glycine imine. Despite being discovered more than 50 years ago, the biosynthetic pathway of KSM remains an unresolved puzzle.
Rajesh Rattinam +9 more
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Uptake and transport of antibiotic kasugamycin in castor bean (Ricinus communis L.) seedlings
Frontiers in Microbiology, 2022 Kasugamycin (KSM), an aminoglycoside antibiotic, has been widely used for the management of plant diseases, especially for the control of rice blast in Asia. However, its uptake mechanism and transport in plants are still obscure.
Hongzhen Zhang +7 more
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Kasugamycin-resistant mutants of Bacillus subtilis [PDF]
Journal of Bacteriology, 1978 Kasugamycin-resistant mutants of Bacillus subtilis were isolated and classified into two groups, one of which had resistance to kasugamycin in in vitro protein synthesis and mapped in the ribosomal region. The other group had no resistance to kasugamycin in in vitro protein synthesis and had weak cross-resistance to gentamicin and kanamycin.
A, Tominaga, Y, Kobayashi
openaire +2 more sources