Structural analysis of kasugamycin inhibition of translation [PDF]
Nature Structural & Molecular Biology, 2006 The prokaryotic ribosome is an important target of antibiotic action. We determined the X-ray structure of the aminoglycoside kasugamycin (Ksg) in complex with the Escherichia coli 70S ribosome at 3.5-A resolution. The structure reveals that the drug binds within the messenger RNA channel of the 30S subunit between the universally conserved G926 and ...
Barbara S, Schuwirth +6 more
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First report in Ghana of Xanthomonas citri pv. mangiferaeindicae causing mango bacterial canker on Mangifera indica [PDF]
, 2011 Bacterial canker of mango (or bacterial black spot), caused by Xanthomonas citri pv. mangiferaeindicae, is an economically important disease in tropical and subtropical producing areas (1). X. citri pv.
C. Boyer +6 more
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C21orf57 is a human homologue of bacterial YbeY proteins [PDF]
, 2017 The product of the human C21orf57 (huYBEY) gene is predicted to be a homologue of the highly conserved YbeY proteins found in nearly all bacteria. We show that, like its bacterial and chloroplast counterparts, the HuYbeY protein is an RNase and that it ...
Babu, Vignesh M.P. +9 more
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Kasugamycin-dependent mutants of Escherichia coli [PDF]
Journal of Bacteriology, 1978 Kasugamycin-dependent mutants have been isolated from Escherichia coli B. They were obtained through mutagenesis with ethyl methane sulfonate or nitrosoguanidine in conjunction with an antibiotic underlay technique. In the case of nitrosoguanidine, dependent mutants were obtained at a frequency of about 3% of survivors growing up in the selection.
openaire +2 more sources
Searching for Blockers of Dengue and West Nile Virus Viroporins
Viruses, 2022 Flavivirus infections, such as those caused by dengue and West Nile viruses, emerge as new challenges for the global healthcare sector. It has been found that these two viruses encode ion channels collectively termed viroporins. Therefore, drug molecules
Hiya Lahiri, Isaiah T. Arkin
doaj +1 more source
A reservoir of 'historical' antibiotic resistance genes in remote pristine Antarctic soils [PDF]
, 2018 Background: Soil bacteria naturally produce antibiotics as a competitive mechanism, with a concomitant evolution, and exchange by horizontal gene transfer, of a range of antibiotic resistance mechanisms.
Bezuidt, Oliver KI +5 more
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Biocontrol of citrus canker with endophyte Bacillus amyloliquefaciens QC-Y
Plant Protection Science, 2021 Citrus canker is an important disease caused by Xanthomonas axonopodis pv. citri that affects citrus species. We isolated a bacterium denominated QC-Y with a strong inhibitory effect on citrus canker from navel orange leaves.
Jialin Qian +6 more
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A Bifunctional Peptide Conjugate That Controls Infections of Erwinia amylovora in Pear Plants
Molecules, 2021 In this paper, peptide conjugates were designed and synthesized by incorporating the antimicrobial undecapeptide BP16 at the C- or N-terminus of the plant defense elicitor peptide flg15, leading to BP358 and BP359, respectively.
Pau Caravaca-Fuentes +9 more
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Stereoselective Glycosylation of 2-Nitrogalactals Catalyzed by a Bifunctional Organocatalyst [PDF]
, 2016 The use of a bifunctional cinchona/thiourea organocatalyst for the direct and α-stereoselective glycosylation of 2-nitrogalactals is demonstrated for the first time.
Balmond, Edward +7 more
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Investigation of the biosynthesis of exopolysaccharides within the biofilm matrix of Pseudomonas aeruginosa and Pseudomonas syringae pv. actinidiea : a thesis presented in partial fulfilment of the requirements for degree of Doctor of Philosophy in Microbiology and Genetics at Massey University, Manawatu, New Zealand [PDF]
, 2017 Polysaccharides are highly abundant natural biopolymers, which have biologically significant structural functions in living organisms. Various polysaccharides, with specific physicochemical properties, contribute to biofilm formation; defined as cell ...
Ghods, Shirin
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