Results 81 to 90 of about 1,507 (202)

Chitinase 3-like-1 is a therapeutic target that mediates the effects of aging in COVID-19

JCI Insight, 2021
COVID-19 is caused by SARS-CoV-2 (SC2) and is more prevalent and severe in elderly and patients with comorbid diseases (CM). Because chitinase 3-like-1 (CHI3L1) is induced during aging and CM, the relationships between CHI3L1 and SC2 were investigated ...
Suchitra Kamle, Bing Ma, Chuan Hua He, Bedia Akosman, Yang Zhou, Chang-Min Lee, Wafik S. El-Deiry, Kelsey Huntington, Olin Liang, Jason T. Machan, Min-Jong Kang, Hyeon Jun Shin, Emiko Mizoguchi, Chun Geun Lee, Jack A. Elias   +14 more
doaj   +1 more source

Peptide ABC-importers determine susceptibility to kasugamycin and blasticidin S in E. coli K-12.

, 2016
(A) Structures of kasugamycin (Ksg) and blasticidin S (BcS). (B) Deletions of peptide importer genes are resistant to kasugamycin and blasticidin S.
Anthony L. Shiver (238214), George Kritikos (505206), Hendrik Osadnik (3162075), Carol A. Gross (498580), Bo Li (112195), Nevan Krogan (7571), Athanasios Typas (505208)   +6 more
core   +1 more source

Unraveling the potency of new antibiotics for managing citrus canker of acid lime in Nepal

Cogent Food & Agriculture
Citrus canker, caused by Xanthomonas citri pv. citri (Xcc), poses a significant threat to acid lime worldwide. Nepalese growers heavily use copper-based compounds, increasing the risk of resistant strains and soil accumulation.
Samikshya Nepal, Shishir Sharma
doaj   +1 more source

The distribution of Kasugamycin resistance in the translatome of E. coli.

, 2017
The KEV value representing a quantitative value of the degree of Kasugamycin resistance was calculated for each of the 2801 analyzed E. coli transcripts as explained in the text.
Christian Lange (70151), Karolin Zerulla (231235), Jens Schweitzer (3637075), Petra Ludwig (3637081), Jörg Soppa (23130), Matthias Lehr (537954), Volker F. Wendisch (1739545), Tino Polen (3637078)   +7 more
core   +1 more source

A common import pathway for kasugamycin and blasticidin S is likely to be conserved across multiple species.

, 2016
Genetic context is shown for importer genes likely to be involved in kasugamycin and blasticidin S uptake for multiple species. Sequence homologues of opp are shown in white. Sequence homologues of dpp are shown in black. The importer npp is shown in red.
Anthony L. Shiver (238214), George Kritikos (505206), Hendrik Osadnik (3162075), Carol A. Gross (498580), Bo Li (112195), Nevan Krogan (7571), Athanasios Typas (505208)   +6 more
core   +1 more source

The chlamydial functional homolog of KsgA confers kasugamycin sensitivity to Chlamydia trachomatis and impacts bacterial fitness

BMC Microbiology, 2009
Background rRNA adenine dimethyltransferases, represented by the Escherichia coli KsgA protein, are highly conserved phylogenetically and are generally not essential for growth.
Maurelli Anthony T, Binet Rachel
doaj   +1 more source

Effects of a commercial biocide, kasugamycin and consistency of the culture medium on the in vitro establishment of bamboo1

, 2019
The contamination by microorganisms and oxidation of explants in the in vitro establishment of bamboo are recurrent problems for its micropropagation.
Miguel Pedro Guerra (8047892), Théo Piucco Rocker (8047886), Daniela Werner Ribeiro dos Santos (8047883), Thiago Sanches Ornellas (8047889)   +3 more
core   +1 more source

Continuous culture of immobilized Streptomyces cells for kasugamycin production

, 2001
Continuous cultures of immobilized Streptomyces kasugaensis, a kasugamycin producer, were carried out an Celite beads. When using a prototype separator for immobilized-cell separation and recycling, the continuous operation could not be sustained for an ...
Lee, SJ, Jeong, YH, Chang, YongKeun, Kim, CJ, Chun, GT   +4 more
core  

The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation

, 2006
Kasugamycin (Ksg) specifically inhibits translation initiation of canonical but not of leaderless messenger RNAs. Ksg inhibition is thought to occur by direct competition with initiator transfer RNA. The 3.35-Å structure of Ksg bound to the 30S ribosomal
Shirouzu, Mikako, Joerg M Harms, Kyoko Hanawa-Suetsugu, Yokoyama, S., Knud H Nierhaus, Hanawa-Suetsugu, K., Tatsuya Kaminishi, Wilson, D., Hanawa-Suetsugu, Kyoko, Fucini, P., Schluenzen, Frank, Paola Fucini, Schluenzen, F., Wilson, Daniel N, Harms, Joerg M ., Shirouzu, M., Mikako Shirouzu, Kaminishi, T., Chie Takemoto, Masahito Kawazoe, Witold Szaflarski, Szaflarski, Witold, Kawazoe, Masahito, Kaminishi, Tatsuya, Nierhaus, Knud, Nierhaus, K., Takemoto, Chie, Fucini, Paola, Yokoyama, Shigeyuki, Harms, J., Frank Schluenzen, Takemoto, C., Daniel N Wilson, Szaflarski, W., Kawazoe, M., Shigeyuki Yokoyama   +35 more
core   +1 more source

Enhancement of kasugamycin production by pH shock in batch cultures of Streptomyces kasugaensis

, 2000
Biosynthesis of kasugamycin could be greatly enhanced by applying a nonnutritional stress of pH shock, that is, sequential pH changes from a neutral pH to an acidic condition and then back to the neutral condition.
Chang, YongKeun, Kim, CJ, Chun, GT
core