Results 101 to 110 of about 32,637 (272)

Nanosilicates Enhanced Periodontal Angiogenesis by Regulating Microtubule Dynamic‐Mediated STAT3 Pathway

open access: yesCell Proliferation, EarlyView.
Nanosilicates triggered MAP4‐dependent microtubule remodelling via the ROS/MAPK pathway, shifting microtubules into a dynamic active state, which subsequently promoted activation of the STAT3 pathway, ultimately facilitating periodontal angiogenesis.
Lingling Shang, Yuhan Hu, Shaohua Ge
wiley   +1 more source

Daily intermittent fasting is an effective multiscale treatment in preclinical models of absence epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Absence epilepsy is characterized by brief but frequent seizures with loss of consciousness. Existing treatments, which come with heavy side effects, are only partially effective and do not address the associated comorbidities, including cognitive and social deficits.
Coline Rulhe   +9 more
wiley   +1 more source

Circulating progenitor cells and their interaction with platelets in patients with an acute coronary syndrome

open access: yesPlatelets, 2019
CD34+ cells expressing KDR (CD34+/KDR+) represent a small proportion of circulating progenitor cells that have the capacity to interact with platelets and to differentiate into mature endothelial cells, thus contributing to vascular homeostasis and ...
Prokopia T. Tatsidou   +7 more
doaj   +1 more source

First report of the Phe1534Cys kdr mutation in natural populations of Aedes albopictus from Brazil

open access: yesParasites & Vectors, 2017
Knockdown resistance (kdr), caused by alterations in the voltage-gated sodium channel (NaV), is one of the mechanisms responsible for pyrethroid (PY) resistance.
O. Aguirre-Obando   +2 more
semanticscholar   +1 more source

EHD4 and ASAP2 are critical negative regulators of the claudin‐5‐based endothelial barrier

open access: yesThe FEBS Journal, EarlyView.
Cell‐surface CLDN‐5 protein levels can be evaluated using a probe that can bind to the extracellular domains of CLDN‐5. A probe derived from Clostridium perfringens enterotoxin allows us to isolate cells with high CLDN‐5 protein levels from a knockout cell library.
Yosuke Hashimoto   +8 more
wiley   +1 more source

CFH (rs1061170, rs1410996), KDR (rs2071559, rs1870377) and KDR and CFH Serum Levels in AMD Development and Treatment Efficacy

open access: yesBiomedicines
Background: Age-related macular degeneration (AMD) is a major global health problem as it is the leading cause of irreversible loss of central vision in the aging population. Av-vascular endothelial growth factor (anti-VEGF) therapies have been shown to be effective, but they do not respond optimally to all patients. Objective.
Dzastina Cebatoriene   +6 more
openaire   +3 more sources

First report of the East African kdr mutation in an Anopheles gambiae mosquito in Côte d’Ivoire

open access: yesWellcome Open Research, 2017
Background. The intensive use of insecticides in public health and agriculture has led to the development of insecticide resistances in malaria vectors across sub-Saharan Africa countries in the last two decades.
Mouhamadou Chouaïbou   +3 more
semanticscholar   +1 more source

The Spleen Promotes Liver Sinusoidal Endothelial Cell Angiogenesis by Stimulating the TGFβ/Smad2/3 Pathway Through GDF15

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aims Liver sinusoidal endothelial cells (LSECs) are crucial nonparenchymal cells involved in liver fibrosis progression. Liver fibrosis develops from various chronic liver diseases, with pathological progression associated with the spleen. However, the precise mechanism by which the spleen influences LSECs during fibrosis is not
Xi Deng   +9 more
wiley   +1 more source

Pyrethroid resistance in the major malaria vector Anopheles arabiensis in Nouakchott, Mauritania

open access: yesParasites & Vectors, 2018
Background Mauritania is one of the African countries with ongoing malaria transmission where data on insecticide resistance of local malaria vectors are limited despite an increasing use of long-lasting insecticide-treated nets (LLINs) as the main ...
Aichetou Mint Mohamed Lemine   +6 more
doaj   +1 more source

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