Results 71 to 80 of about 32,637 (272)

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source

Multiple insecticide resistance in Anopheles gambiae from Tanzania: a major concern for malaria vector control

Malaria Journal, 2017
Background Malaria vector control in Tanzania is based on use of long-lasting insecticide treated nets (LLINs) and indoor residual spraying (IRS), which both rely on the use of chemical insecticides. The effectiveness of these control tools is endangered
William N. Kisinza, Theresia E. Nkya, Bilali Kabula, Hans J. Overgaard, Dennis J. Massue, Zawadi Mageni, George Greer, Naomi Kaspar, Mahdi Mohamed, Richard Reithinger, Sarah Moore, Lena M. Lorenz, Stephen Magesa   +12 more
doaj   +1 more source

Bayesian Inference Associates Rare KDR Variants With Specific Phenotypes in Pulmonary Arterial Hypertension

bioRxiv, 2019
Background Approximately 25% of patients with pulmonary arterial hypertension (PAH) have been found to harbor rare mutations in disease-causing genes.
E. Swietlik, D. Greene, N. Zhu, Karyn Megy, Marcella Cogliano, S. Rajaram, D. Pandya, T. Tilly, K. Lutz, C. Welch, M. Pauciulo, L. Southgate, Jennifer M Martin, C. Treacy, C. Penkett, J. Stephens, H. Bogaard, C. Church, G. Coghlan, A. Coleman, R. Condliffe, M. Eyries, H. Gall, S. Ghio, B. Girerd, S. Holden, L. Howard, M. Humbert, D. Kiely, G. Kovacs, J. Lordan, R. Machado, R. Ross, C. McCabe, S. Moledina, D. Montani, H. Olschewski, J. Pepke-Zaba, L. Price, C. Rhodes, W. Seeger, F. Soubrier, J. Suntharalingam, M. Toshner, A. Noordegraaf, J. Wharton, J. Wild, S. Wort, A. Lawrie, M. Wilkins, R. Trembath, Yufeng Shen, W. Chung, A. Swift, W. Nichols, N. Morrell, S. Gräf   +56 more
semanticscholar   +1 more source

Absence of knockdown mutations in pyrethroid and DDT resistant populations of the main malaria vectors in Colombia

Malaria Journal, 2019
Background Knockdown resistance (kdr) is a well-characterized target-site insecticide resistance mechanism that is associated with DDT and pyrethroid resistance.
Lorena I. Orjuela, Diego A. Álvarez-Diaz, Juliana A. Morales, Nelson Grisales, Martha L. Ahumada, Juan Venegas H, Martha L. Quiñones, María F. Yasnot   +7 more
doaj   +1 more source

Status of insecticide resistance and its biochemical and molecular mechanisms in Anopheles stephensi (Diptera: Culicidae) from Afghanistan

Malaria Journal, 2019
Background Insecticide resistance of Anopheles stephensi, the main malaria vector in eastern Afghanistan, has been reported previously. This study describes the biochemical and molecular mechanisms of resistance to facilitate effective vector control and
Noor Halim Zahid Safi, Abdul Ali Ahmadi, Sami Nahzat, Supriya Warusavithana, Naimullah Safi, Reza Valadan, Atie Shemshadian, Marzieh Sharifi, Ahmadali Enayati, Janet Hemingway   +9 more
doaj   +1 more source

ANLN and KDR Are Jointly Prognostic of Breast Cancer Survival and Can Be Modulated for Triple Negative Breast Cancer Control

Frontiers in Genetics, 2019
Purpose: Kinase insert domain receptor (KDR) is the primary vascular endothelial growth factor receptor mediating survival, growth, and migration of endothelial cells and is expressed also in various tumor cells through autocrine production.
Xiaofeng Dai, Yi Mei, Xiao Chen, Dong-yan Cai   +3 more
semanticscholar   +1 more source

Exercise serum promotes DNA damage repair and remodels gene expression in colon cancer cells

International Journal of Cancer, EarlyView.
What's New? Exercise releases bioactive molecules into the bloodstream that can directly slow cancer cell growth. In colon cancer, this may help limit disease progression. Here, using colon cancer cells, the authors investigated the effects of exercise‐conditioned human serum on DNA repair mechanisms. Notably, acute exercise in humans elicited systemic
Samuel T. Orange, Emily Dodd, Sharanya Nath, Hannah Bowden, Alastair R. Jordan, Hannah Tweddle, Ann Hedley, Ifeoma Chukwuma, Ian Hickson, Sweta Sharma Saha   +9 more
wiley   +1 more source

Establishment of an innovative and sustainable PCR technique for 1534 locus mutation of the knockdown resistance (kdr) gene in the dengue vector Aedes albopictus

Parasites & Vectors, 2019
Background Mutation of the voltage-gated sodium channel (VGSC) gene, or knockdown resistance (kdr) gene, is an important resistance mechanism against DDT and pyrethroids for dengue vector Aedes albopictus.
Cai-Ying Zhu, Chun-Chun Zhao, Yi-Guan Wang, De-Ling Ma, Xiu-Ping Song, Jun Wang, Feng-Xia Meng   +6 more
doaj   +1 more source

Pyrethroid resistance in the dengue vector Aedes aegypti in Southeast Asia: present situation and prospects for management

Parasites & Vectors, 2018
Human arboviral diseases transmitted by Aedes aegypti such as dengue, Zika, chikungunya and yellow fever remain global public health threats to date. Of these diseases, dengue fever is particularly prevalent in Southeast Asia.
Zheng Hua Amelia-Yap, Chee Dhang Chen, Mohd Sofian-Azirun, Van Lun Low   +3 more
doaj   +1 more source

Establishing the resistance of Myzus persicae (Sulzer) by molecular methods [PDF]

Archives of Biological Sciences, 2008
In two years of investigating resistance of the peach-potato aphid Myzus persicae (Sulzer) by molecular methods, several types of resistance were established in the majority of individuals from peach and tobacco in Serbia and Montenegro.
Vučetić Anđa, Petrović-Obradović Olivera, Margaritopoulos J., Skouras P.   +3 more
doaj   +1 more source