Results 71 to 80 of about 9,255 (204)

Experimental hut evaluation of bednets treated with an organophosphate (chlorpyrifos-methyl) or a pyrethroid (lambdacyhalothrin) alone and in combination against insecticide-resistant Anopheles gambiae and Culex quinquefasciatus mosquitoes. [PDF]

, 2005
BACKGROUND: Pyrethroid resistant mosquitoes are becoming increasingly common in parts of Africa. It is important to identify alternative insecticides which, if necessary, could be used to replace or supplement the pyrethroids for use on treated nets ...
Chandre Fabrice, Alphonsine A Koffi, Darriet, Frédéric, Asidi, A.N., Zaim, M., Zaim, Morteza, Koffi, A.A., Frédéric Darriet, Asidi, AN, N'Guessan, R., Curtis Christopher F, Hougard, Jean-Marc, Asidi Alex N, Corbel, V, Morteza Zaim, Chandre, F, Asidi, Alex N, Hougard, JM, Rowland, Mark W, Hougard Jean-Marc, N'Guessan, Raphael, Vincent Corbel, N' Guessan Raphael, Chandre, Fabrice, Curtis, C.F., Curtis, Christopher F, Mark W Rowland, Christopher F Curtis, Corbel Vincent, Darriet Frédéric, Koffi, Alphonsine A, Koffi, AA, Rowland, MW, Rowland Mark W, Fabrice Chandre, Rowland, M.W., Raphael N' Guessan, N'Guessan, R, Jean-Marc Hougard, Zaim Morteza, Darriet, F, Curtis, CF, Alex N Asidi, Corbel, Vincent, Zaim, M, Koffi Alphonsine A   +45 more
core   +1 more source

Targeting METTL3 Attenuates Thyroid Inflammatory Injury by Restoring Th17/Treg Balance through a YTHDC2‐m6A‐Dependent KDR/VEGFA Loop

Advanced Science, EarlyView.
METTL3‐mediated m6A modification stabilizes KDR/Kdr mRNA through YTHDC2, amplifying the VEGFA‐KDR feedback loop and disturbing Th17/Treg balance. This pathway promotes persistent inflammation and tissue damage in patients with AIT, and inhibiting the METTL3‐KDR axis effectively disrupts this circuit, alleviating thyroid tissue injury and disease ...
Qingyi Hu, Huan Liu, Anwen Ren, Zimei Tang, Jie Tan, Wen Yang, Jie Ming, Tao Huang   +7 more
wiley   +1 more source

α2,3‐Sialyltransferase (ST3Gal1) regulates endometrioid‐type epithelial ovarian cancer cell migration and invasion via VEGF‐R2/JAK2/STAT3 signaling cascades

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To investigate the role of ST3 β‐galactoside α‐2,3‐sialyltransferase 1 (ST3Gal1) and vascular endothelial growth factor receptor 2 (VEGF‐R2) in endometrioid‐type epithelial ovarian cancer (E‐OC) because aberrant α2,3‐sialylation mediated by ST3Gal1 and VEGF‐R2‐related angiogenesis is linked with tumor progression. Methods ST3Gal1 and
Wei‐Ting Chao, Chia‐Hao Liu, Szu‐Ting Yang, Chen‐Hao Lin, Liang‐Wei Wang, Peng‐Hui Wang   +5 more
wiley   +1 more source

First report of N1575Y mutation in pyrethroid resistant Anopheles gambiae s.l. in Nigeria

Scientific African, 2020
In view of recent findings that codon 1575 mutation increases the L1014F-mediated resistance in Anopheles mosquitoes, we investigated the presence of this mutation in four States with intense pyrethroid resistance in Nigeria.
A. Tolulope Oyeniyi, A. Olufemi Adeogun, E. Taiwo Idowu, Bola Oboh, Abiodun Olakiigbe, Oluwakemi Adesalu, Tawakalitu Jimoh, T. Samson Awolola   +7 more
doaj   +1 more source

First report of the L1014S kdr mutation in wild populations of Anopheles gambiae M and S molecular forms in Burkina Faso (West Africa)

, 2013
We investigated the occurrence of the L1014F and L1014S kdr mutations in malaria vector populations in Burkina Faso (West Africa). A cross-sectional survey was conducted at 10 sites all located in cotton cultivation areas which are assumed to be the ...
Namountougou, M., Simard, Frédéric, Dabiré, R. K., Simard, F., Martin, T., Baldet, Thierry, Diabaté, A., Etang, J., Bass, C. G., Namountougou, Moussa, Martin, Thibaud, Bass, C., Baldet, T., Diabaté, Abdoulaye, Etang, Josiane, Sawadogo, S. P., Gnankinié, O., Dabiré, Roch Kounbobr, Gnankine, Olivier, Bass, Chris, Chandre, F., Sawadogo, Simon P., Chandre, Fabrice   +22 more
core   +1 more source

kdr mutations and deltamethrin resistance in house flies in Abu Dhabi, UAE

Parasites & Vectors
Abstract Background The house fly, Musca domestica, is a significant carrier of diseases that can impact public health. Repeated use of pyrethroid insecticides may act as a selection pressure for mutations and amino acid substitutions in the house fly voltage-sensitive sodium channel (VSSC), which ultimately confers ...
Mohamad Hamdan, Tamilarasan Kamalanathan, Asim Iqbal, Antony Raj Gnanaprakasam, Sabu Shajahan, Mohammad Hamad Alsadeq, Amgd sayed Ali, Mohammad Ali Al-Deeb   +7 more
openaire   +3 more sources

Surveillance of a kdr Resistance Mutation in Culex pipiens (Diptera: Culicidae) and Culex quinquefasciatus in California [PDF]

Journal of Medical Entomology, 2019
Abstract Culex pipiens Linnaeus and Culex quinquefasciatus Say are the primary vectors of West Nile and St. Louis encephalitis viruses in California. Pyrethrins and pyrethroids (synthetic pyrethrins) are the most widely used insecticides to control adult stage mosquitoes to prevent disease transmission.
Vicki Kramer, Kerry Padgett, Melissa Hardstone Yoshimizu   +2 more
openaire   +2 more sources

SYN‐A, a naturally derived synergist, restores pyrethroid efficacy against cabbage stem flea beetle but negatively impacts its parasitoid Microctonus brassicae

Pest Management Science, EarlyView.
SYN‐A, a naturally derived synergist, inhibited key metabolic pathways associated with pyrethroid insecticide resistance in cabbage stem flea beetle (CSFB) and its parasitoid Microctonus brassicae. SYN‐A restored pyrethroid efficacy against resistant CSFB allowing up to 80% reduction in application rates.
Patricia A. Ortega‐Ramos, Graham D. Moores, Samantha M. Cook   +2 more
wiley   +1 more source

Pyrethroid resistance in Anopheles gambiae, in Bomi County, Liberia, compromises malaria vector control. [PDF]

, 2012
BACKGROUND: Long Lasting Insecticidal Nets (LLIN) and Indoor Residual Spraying (IRS) have both proven to be effective malaria vector control strategies in Africa and the new technology of insecticide treated durable wall lining (DL) is being evaluated ...
Avicor, Silas W, Silas W Avicor, Howard, Annabel F.V., Allan, Richard, Maxwell Caroline, Kleinschmidt, Immo, Richard Allan, Annabel F V Howard, Allan Richard, Munyekenye, Godwil, Caroline Maxwell, Emmanuel A Temu, Kleinschmidt Immo, Temu, Emmanuel A., Ranson, Hilary, Avicor, Silas W., Jones, Joel J., Temu Emmanuel A., Munga Stephen, Godwil Munyekenye, Joel J Jones, Howard Annabel F. V., Poupardin, Rodolphe, Temu, Emmanuel A, Howard, Annabel FV, Rodolphe Poupardin, Maxwell, Caroline, Avicor Silas W., Immo Kleinschmidt, Ranson, Hilary; id_orcid, Jones Joel J., Jones, Joel J, Stephen Munga, Munyekenye Godwil, Poupardin Rodolphe, Munga, Stephen, Hilary Ranson, Ranson Hilary   +37 more
core   +1 more source

Long‐term impact of exposure to Royal Guard, a pyriproxyfen‐based bed net, on pyrethroid‐resistant malaria vectors from Cameroon using DNA‐based metabolic resistance markers

Pest Management Science, Volume 81, Issue 4, Page 2165-2180, April 2025.
We used recently detected P450 DNA‐based markers of pyrethroid resistance in both Anopheles funestus and Anopheles gambiae to demonstrate that although pyrethroid‐resistant mosquitoes have higher ability to survive and live longer after exposure to Royal Guard, this net significantly affects their lifespan, blood feeding ability and interestingly ...
Emilie S Ngongang‐Yipmo, Magellan Tchouakui, Benjamin D Menze, Riccado F Tiomela, Derrick Fofie, Vanessa B Ngannang‐Fezeu, Jean L Mugenzi, Flobert Njiokou, Charles S Wondji   +8 more
wiley   +1 more source