Results 81 to 90 of about 544,512 (208)

Surveillance of a kdr Resistance Mutation in Culex pipiens (Diptera: Culicidae) and Culex quinquefasciatus in California [PDF]

Journal of Medical Entomology, 2019
Abstract Culex pipiens Linnaeus and Culex quinquefasciatus Say are the primary vectors of West Nile and St. Louis encephalitis viruses in California. Pyrethrins and pyrethroids (synthetic pyrethrins) are the most widely used insecticides to control adult stage mosquitoes to prevent disease transmission.
Vicki Kramer, Kerry Padgett, Melissa Hardstone Yoshimizu   +2 more
openaire   +2 more sources

SYN‐A, a naturally derived synergist, restores pyrethroid efficacy against cabbage stem flea beetle but negatively impacts its parasitoid Microctonus brassicae

Pest Management Science, EarlyView.
SYN‐A, a naturally derived synergist, inhibited key metabolic pathways associated with pyrethroid insecticide resistance in cabbage stem flea beetle (CSFB) and its parasitoid Microctonus brassicae. SYN‐A restored pyrethroid efficacy against resistant CSFB allowing up to 80% reduction in application rates.
Patricia A. Ortega‐Ramos, Graham D. Moores, Samantha M. Cook   +2 more
wiley   +1 more source

First report of the L1014S kdr mutation in wild populations of Anopheles gambiae M and S molecular forms in Burkina Faso (West Africa)

, 2013
We investigated the occurrence of the L1014F and L1014S kdr mutations in malaria vector populations in Burkina Faso (West Africa). A cross-sectional survey was conducted at 10 sites all located in cotton cultivation areas which are assumed to be the ...
Namountougou, M., Simard, Frédéric, Dabiré, R. K., Simard, F., Martin, T., Baldet, Thierry, Diabaté, A., Etang, J., Bass, C. G., Namountougou, Moussa, Martin, Thibaud, Bass, C., Baldet, T., Diabaté, Abdoulaye, Etang, Josiane, Sawadogo, S. P., Gnankinié, O., Dabiré, Roch Kounbobr, Gnankine, Olivier, Bass, Chris, Chandre, F., Sawadogo, Simon P., Chandre, Fabrice   +22 more
core   +1 more source

The first report of M918L (super‐kdr) and L932F voltage‐gated sodium channel mutations in the English grain aphid (Sitobion avenae)

Pest Management Science, EarlyView.
The study has identified mutations in the voltage gated sodium channel of the English grain aphid (Sitobion avenae) at M918 and L932, which have not been previously reported in this species. Abstract BACKGROUND The grain aphid, Sitobion avenae Fabricius (Hemiptera: Aphididae), is a vector of yellow dwarf viruses and an important pest of cereals.
Virgile Ballandras, Louise McNamara, James C Carolan, Tom Ruttink, Stephen Byrne   +4 more
wiley   +1 more source

KDR Mutation: A High-Frequency Rare Mutation and its Correlation with other Somatic Mutations in Indian Colorectal Cancer Patients

Journal of Next Generation Sequencing & Applications, 2017
Aim: This study aims to find out the frequency of KDR mutation in colorectal cancer patients and if any correlation exists between KDR mutation and demographical features or with other common and uncommon gene mutations occurring in colon cancer. Methods: FFPE samples of 112 patients were analyzed using next generation sequencing.
Mayank Jauhri, Vani Gupta, Yogender Shokeen, Sachin Minhas, Sunita Bhalla, Shyam Aggarwal   +5 more
openaire   +1 more source

Diversity and frequency of kdr mutations within Anopheles sinensis populations from Guangxi, China [PDF]

Malaria Journal, 2016
Anopheles sinensis is a major vector of malaria in China and its control is under great threat as the development of insecticide resistance. Voltage-gated sodium channel (VGSC) is the target of several classes of insecticides. Genetic mutations of VGSC have been documented to confer knockdown resistance (kdr) to dichlorodiphenyltrichloroethane (DDT ...
Yang, Chan, Feng, Xiangyang, Huang, Zushi, Li, Mei, Qiu, Xinghui   +4 more
openaire   +2 more sources

Target‐site mutations and phenotypic failure in Myzus persicae against pyrethroids and carbamates in central Europe

Pest Management Science, EarlyView.
Molecular screening of 140 field‐collected Myzus persicae aphids revealed target‐site mutations L1014F, M918L, M918T, and L932F in the sodium channel and S431F in Ace2. The M918L mutation was the primary driver of high pyrethroid (cypermethrin) resistance, while S431F served as a definitive marker for carbamate (pirimicarb) resistance.
Jitka Stara, Jan Hubert, Pavla Pabiskova, Frantisek Kocourek   +3 more
wiley   +1 more source

Status of insecticide susceptibility in Anopheles arabiensis and detection of the knockdown resistance mutation (kdr) concerning agricultural practices from Northern Sudan state, Sudan

Journal of Genetic Engineering and Biotechnology, 2021
Background Chemical control has been the most efficient method in mosquito control, the development of insecticide resistance in target populations has a significant impact on vector control.
M. Y. Korti, T. B. Ageep, A. I. Adam, K. B. Shitta, A. A. Hassan, A. A. Algadam, R. M. Baleela, H. A. Saad, S. A. Abuelmaali   +8 more
doaj   +1 more source

Long‐term impact of exposure to Royal Guard, a pyriproxyfen‐based bed net, on pyrethroid‐resistant malaria vectors from Cameroon using DNA‐based metabolic resistance markers

Pest Management Science, Volume 81, Issue 4, Page 2165-2180, April 2025.
We used recently detected P450 DNA‐based markers of pyrethroid resistance in both Anopheles funestus and Anopheles gambiae to demonstrate that although pyrethroid‐resistant mosquitoes have higher ability to survive and live longer after exposure to Royal Guard, this net significantly affects their lifespan, blood feeding ability and interestingly ...
Emilie S Ngongang‐Yipmo, Magellan Tchouakui, Benjamin D Menze, Riccado F Tiomela, Derrick Fofie, Vanessa B Ngannang‐Fezeu, Jean L Mugenzi, Flobert Njiokou, Charles S Wondji   +8 more
wiley   +1 more source

KDR Mutation as a Novel Predictive Biomarker of Exceptional Response to Regorafenib in Metastatic Colorectal Cancer [PDF]

Cureus, 2016
This is the case of an 84-year-old woman diagnosed with Stage IVb colon adenocarcinoma (CRC) metastatic to the liver, retroperitoneum, anastomotic site, and distal rectal sigmoid colon. She experienced intolerable side effects to systemic chemotherapy with 5-fluorouracil and bevacizumab, as well as disease progression. Next generation sequencing of her
Loaiza-Bonilla, Arturo, Jensen, Christopher E, Shroff, Stuti, Furth, Emma, Bonilla-Reyes, Paula A, Deik, Andres F, Morrissette, Jennifer   +6 more
openaire   +2 more sources