Results 91 to 100 of about 9,255 (204)

Frequencies of Kdr (West Africa) mutation in Cx quinquefasciatus population from Yaoundé.

open access: yes, 2019
Frequencies of Kdr (West Africa) mutation in Cx quinquefasciatus population from Yaoundé.
Edmond Kopya (3467846)   +10 more
core   +1 more source

Full‐length coding sequence analysis of the voltage‐gated sodium channel and acetylcholinesterase genes reveals target‐site mutations and acetylcholinesterase gene duplication in housefly (Musca domestica) populations in Japanese livestock barns

open access: yesMedical and Veterinary Entomology, EarlyView.
We simultaneously analysed insecticide resistance mutations in VGSC and AChE using NGS and hybridization probe capture in houseflies collected from livestock facilities for the first time. Resistance mutations in both VGSC and AChE were detected in most wild populations, suggesting widespread distribution of resistance genes.
Mikie Nakagawa   +7 more
wiley   +1 more source

Understanding exosomes in regenerative dentistry

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad   +2 more
wiley   +1 more source

KDR Mutation as a Novel Predictive Biomarker of Exceptional Response to Regorafenib in Metastatic Colorectal Cancer [PDF]

open access: yesCureus, 2016
This is the case of an 84-year-old woman diagnosed with Stage IVb colon adenocarcinoma (CRC) metastatic to the liver, retroperitoneum, anastomotic site, and distal rectal sigmoid colon. She experienced intolerable side effects to systemic chemotherapy with 5-fluorouracil and bevacizumab, as well as disease progression. Next generation sequencing of her
Loaiza-Bonilla, Arturo   +6 more
openaire   +2 more sources

Climatic, Socioecological and Environmental Determinants of Aedes spp. Dynamics at the Community Interface: A Systematic Review With Reflections From a One Health Perspective

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Background and Objectives Mosquitoes of the genus Aedes, including but not limited to Aedes aegypti, are major vectors of arboviruses such as dengue, Zika and other related diseases. Their global expansion is driven by climate change, globalisation, urbanisation and human mobility.
Ana Izabel Passarella Teixeira   +8 more
wiley   +1 more source

Comparative Response of Canine and Human Osteosarcoma Tumour Cell Lines to Molecularly Targeted Anticancer Agents at Clinically Relevant Exposures With Analysis of Genomic Biomarkers

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT Osteosarcoma (OSA) is a primary bone tumour occurring in children but is also prevalent in large breed dogs. Canine OSA (cOSA) has long been viewed as analogous to human OSA (hOSA) with cOSA serving as a surrogate for development of therapeutic approaches to treat the rarer human form.
Daniel L. Gustafson   +5 more
wiley   +1 more source

Deteksi Resistensi Piretroid Secara Bioassay dan Mutasi Gen kdr pada Aedes aegypti dan Aedes albopictus

open access: yesMajalah Kedokteran Andalas
Objective: The aim of this study is to detect the insecticide resistance by bioassay test and to detect the kdr mutation in Aedes aegypti and Aedes albopictus.
Puti Reno Diandra K.   +5 more
doaj   +1 more source

Mutation profiling of anaplastic ependymoma grade III by Ion Proton next generation DNA sequencing [version 2; peer review: 2 approved]

open access: yesF1000Research, 2020
Background: Ependymomas are glial tumors derived from differentiated ependymal cells. In contrast to other types of brain tumors, histological grading is not a good prognostic marker for these tumors.
Ejaz Butt   +9 more
doaj   +1 more source

Update on resistance status of Anopheles gambiae s.s. to conventional insecticides at a previous WHOPES field site, "Yaokoffikro", 6 years after the political crisis in Côte d'Ivoire. [PDF]

open access: yes, 2012
BACKGROUND: At Yaokoffikro field site near Bouaké, in central Côte d'Ivoire, a group of experimental huts built in 1996 served over many years for the evaluation of insecticides against highly resistant mosquitoes.
Chandre Fabrice   +22 more
core   +1 more source

Amyloid‐β aggregates induce vasculopathy via ferroptosis in brain endothelial cells

open access: yesBrain Pathology, Volume 36, Issue 4, July 2026.
Blood–brain barrier (BBB) disruption is evident in brains with amyloidopathy. In this study, we demonstrate that amyloid β (Aβ) drives abnormal lipid metabolism and lipid droplet formation in brain endothelial cells, leading to lipid peroxidation and ferroptosis.
Suhyeon Son   +7 more
wiley   +1 more source

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