Results 71 to 80 of about 40,839 (332)
Ferrostatin-1 inhibits fibroblast fibrosis in keloid by inhibiting ferroptosis [PDF]
PeerJBackground Keloid is a chronic proliferative fibrotic disease caused by abnormal fibroblasts proliferation and excessive extracellular matrix (ECM) production.
Liu Yang, Xiuli Li, Yanli Wang
doaj +2 more sources
Quality of life in black African patients with keloid scars
Dermatology Reports, 2020 A keloid scar is a benign skin tumor and we aimed to assess the Quality of Life (QoL) of black Africans with keloid scars based on the Dermatology Life Quality Index (DLQI).
Komenan Kassi +7 more
doaj +1 more source
Research progress in the pathogenesis of keloids
Pifu-xingbing zhenliaoxue zazhi, 2023 During the process of skin wound healing, hyperproliferation of fibroblasts and excessive deposition of collagen in the extracellular matrix lead to the formation of keloid, a benign tumor with characteristics of aggressive growth.
Kunpeng JIA, Jing ZHOU
doaj +1 more source
GLUT-1 Enhances Glycolysis, Oxidative Stress, and Fibroblast Proliferation in Keloid
Life, 2021 A keloid is a fibroproliferative skin tumor. Proliferating keloid fibroblasts (KFs) demand active metabolic utilization. The contributing roles of glycolysis and glucose metabolism in keloid fibroproliferation remain unclear. This study aims to determine
Ying‐Yi Lu +4 more
semanticscholar +1 more source
Animal Models and Experimental Medicine, EarlyView.Animal models remain indispensable in the study of pathological scars, each offering unique advantages and constraints. Their integration with in vitro and ex vivo systems is key to developing personalized, clinically translatable antifibrotic therapies. Abstract Pathological scarring, manifested in the form of hypertrophic scars (HTS) and keloid scars
Diana‐Larisa Ancuța +3 more
wiley +1 more source
A Role for Neuregulin-1 in Promoting Keloid Fibroblast Migration via ErbB2-mediated Signaling
Acta Dermato-Venereologica, 2017 Keloid disease is a fibroproliferative tumour characterised by aggressive local invasion, evident from a clinically and histologically active migrating margin.
Natalie Jumper +3 more
doaj +1 more source
British Journal of Dermatology, 2020 Our understanding of the pathogenesis underlying keloid scar formation is still very limited, and the morphological distinction between hypertrophic and keloid scars remains difficult.
G. C. Limandjaja +4 more
semanticscholar +1 more source
Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment
BMEMat, EarlyView.Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan +8 more
wiley +1 more source
Analysis Of Genetic Association Of TGFΒ1 And SMAD4 Genes With Keloid In Malay Population [PDF]
, 2012 Keloid is a complex condition with environmental and genetic risk-contributing factors. Two candidate genes, TGFβ1 and SMAD4, located in the same signaling pathway are highly expressed in the keloid fibroblast cells. The present study investigated the
Azadeh, Emami
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