Results 11 to 20 of about 24,369 (267)
Adjuvant Radiotherapy after Surgical Excision in Keloids
Medicina, 2021 Keloids are a benign fibroproliferative disease with a high tendency of recurrence. Keloids cause functional impairment, disfigurement, pruritus, and low quality of life. Many therapeutic options have been used for keloids.
Jeong Won Lee, Ki Ho Seol
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Plastic and Reconstructive Surgery, 2021 Background: In 2010, this Journal published my comprehensive review of the literature on hypertrophic scars and keloids. In that article, I presented evidence-based algorithms for the prevention and treatment of these refractory pathologic scars.
R. Ogawa
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Journal of Investigative Dermatology, 2022 Studies on the etiopathogenesis of keloids mostly have focused on fibroblasts (FBs) and their dysfunction. In this study, two cutting-edge technologies, single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST), were applied to uncover the ...
J. Shim +7 more
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Decoding the molecular landscape of keloids: new insights from single-cell transcriptomics
Burns & Trauma, 2023 Keloids are a fibrotic disease caused by an excessive accumulation of extracellular matrix in the dermis; they have neoplasia-like properties of aggressive growth and high posttreatment recurrence rates.
Yijun Xia +4 more
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The Communication from Immune Cells to the Fibroblasts in Keloids: Implications for Immunotherapy
International Journal of Molecular Sciences, 2023 Keloids are a type of fibrotic disease characterized by excessive collagen production and extracellular matrix (ECM) deposition. The symptoms of pain and itching and frequent recurrence after treatment significantly impact the quality of life and mental ...
Xiya Zhang, Xinfeng Wu, Dongqing Li
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Journal of Investigative Dermatology, 2021 Keloids are a benign dermal fibrotic disorder with features similar to malignant tumors. keloids remain a therapeutic challenge and lack medical therapies, which is partially due to the incomplete understanding of the pathogenesis mechanism. We performed
Xuanyu Liu +9 more
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Characterization of the skin keloid microenvironment
Cell Communication and Signaling, 2023 Keloids are a fibroproliferative skin disorder that develops in people of all ages. Keloids exhibit some cancer-like behaviors, with similar genetic and epigenetic modifications in the keloid microenvironment.
Mengwen Zhang +3 more
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BMC Surgery, 2021 Background Although multiple methods have been proposed to treat auricular keloids, low curative effects and high recurrence rates are currently major clinical problems.
Qiang Sun +5 more
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Indian Journal of Dermatology, 2023 Purpose: This study aimed to explore the clinical effects of pulsed dye laser (PDL) dynamically combined with triamcinolone acetonide (TAC) in the treatment of post-operative keloids recurrence.
Zhennan Liu, Jiamin Zhang, Xin Guo
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Dasatinib Attenuates Fibrosis in Keloids by Decreasing Senescent Cell Burden
Acta Dermato-Venereologica, 2023 Keloids are skin tumours caused by aberrant growth of dermal fibroblasts. Cellular senescence contributes to aging and various pathological conditions, including cancer, atherosclerosis, and fibrotic diseases.
Claudia C. Darmawan +5 more
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