Results 31 to 40 of about 24,369 (267)

Genomic and proteomic profiling II: Comparative assessment of gene expression profiles in leiomyomas, keloids, and surgically-induced scars [PDF]

open access: yes, 2007
Background Leiomyoma have often been compared to keloids because of their fibrotic characteristic and higher rate of occurrence among African Americans as compared to other ethnic groups.
Xiaoping Luo   +3 more
core   +1 more source

Recent Understandings of Biology, Prophylaxis and Treatment Strategies for Hypertrophic Scars and Keloids

open access: yesInternational Journal of Molecular Sciences, 2018
Hypertrophic scars and keloids are fibroproliferative disorders that may arise after any deep cutaneous injury caused by trauma, burns, surgery, etc. Hypertrophic scars and keloids are cosmetically problematic, and in combination with functional problems
Ho Jun Lee, Y. Jang
semanticscholar   +1 more source

RNA Sequencing Keloid Transcriptome Associates Keloids With Th2, Th1, Th17/Th22, and JAK3-Skewing

open access: yesFrontiers in Immunology, 2020
Keloids are disfiguring, fibroproliferative growths and their pathogenesis remains unclear, inhibiting therapeutic development. Available treatment options have limited efficacy and harbor safety concerns.
Jianni Wu   +9 more
semanticscholar   +1 more source

The Keloid Disorder: Heterogeneity, Histopathology, Mechanisms and Models

open access: yesFrontiers in Cell and Developmental Biology, 2020
Keloids constitute an abnormal fibroproliferative wound healing response in which raised scar tissue grows excessively and invasively beyond the original wound borders.
Grace C. Limandjaja   +4 more
doaj   +1 more source

Reconstructed human keloid models show heterogeneity within keloid scars [PDF]

open access: yes, 2018
Keloid scars are often described as having an actively growing peripheral margin with a regressing centre. The aim of this study was to examine the possible heterogeneity within keloids and the involvement of different regions within and around keloid ...
Breetveld, Melanie   +7 more
core   +3 more sources

The increased prevalence of keloids in atopic dermatitis patients with allergic comorbidities: a nationwide retrospective cohort study

open access: yesScientific Reports, 2021
Atopic dermatitis (AD) is associated with allergic comorbidities, such as asthma, allergic rhinitis (AR), and allergic contact dermatitis (ACD). The etiology of keloid is largely unknown; however, AD and keloid share inflammatory pathways characterized ...
Hyo-Eun Kwon   +3 more
doaj   +1 more source

Increased epidermal thickness and abnormal epidermal differentiation in keloid scars [PDF]

open access: yes, 2016
Background: The pathogenesis underlying keloid formation is still poorly understood. Research has focused mostly on dermal abnormalities, while the epidermis has not yet been studied.
Everts, V   +8 more
core   +3 more sources

Circular RNAs: Emerging players in the pathogenesis of keloid

open access: yesFrontiers in Physiology, 2022
Circular RNAs (circRNAs) are a new type of non-coding RNAs originating from precursor messenger RNAs. Recent research has confirmed that circRNAs play a significant role in various biological and pathological processes, including cell viability ...
Xin Yu   +3 more
doaj   +1 more source

ANDROGEN-DEPENDENT DERMOPATHY IN WOMEN WITH KELOID SCARS

open access: yesПаёми Сино, 2019
Objective: To explore the character of androgen-dependent dermopathy (ADD) in women with keloid scars. Methods: 100 girls and women aged 15-28 years were examined, of whom 47 were with «true» and 53 were with «false» keloids.
M.S. VALIEVA   +3 more
doaj   +1 more source

Keloids and Hypertrophic Scars: Update and Future Directions [PDF]

open access: yes, 2014
Summary: The development of cutaneous pathological scars, namely, hypertrophic scars (HSs) and keloids, involves complex pathways, and the exact mechanisms by which they are initiated, evolved, and regulated remain to be fully elucidated.
Akaishi, Satoshi   +3 more
core   +1 more source

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