Results 31 to 40 of about 9,857 (229)

Nd: YAG Laser Treatment for Keloids and Hypertrophic Scars: An Analysis of 102 Cases

Plastic and Reconstructive Surgery, Global Open, 2014
Background: The present retrospective cohort study was performed to determine the efficacy of contact-mode 1064 nm neodymium-yttrium-aluminum-garnet (Nd:YAG) laser laser for keloids and hypertrophic scars.
Sachiko Koike, MD, Satoshi Akaishi, MD, PhD, Yuki Nagashima, MD, Teruyuki Dohi, MD, Hiko Hyakusoku, MD, PhD, Rei Ogawa, MD, PhD, FACS   +5 more
doaj   +1 more source

KELOID; PRODUCTION OF KELOID ANIMAL MODEL

THE PROFESSIONAL MEDICAL JOURNAL, 2016
Keloids and hypertrophic scars are basically an overabundance of fibrosis in cutaneous healing process. Unfortunately, keloids are only found in human beings. So far no successful animal model of keloid has been reported. Objectives: To produce an animal model of keloid. Main Outcome Measure: Animal model of keloid.
Abdul Mannan Babar, Abdul Hannan Nagi
openaire   +2 more sources

Treatment of retroauricular keloids: Revision of cases treated at the ENT service of HC/UFPR

International Archives of Otorhinolaryngology, 2012
Introduction: Keloids are benign tumors arising from abnormal healing of the skin, and there are several procedures available for their treatment. Objective: The objective of this study was to evaluate the outcomes of patients undergoing ...
Bettina Carvalho, Annelyse Cristine Ballin, Renata Vecentin Becker, Talita Beithum Ribeiro, Juliana Benthien Cavichiolo, Carlos Roberto Ballin, Marcos Mocellin   +6 more
doaj   +3 more sources

Myofibroblasts Are Not Characteristic Features of Keloid Lesions

Plastic and Reconstructive Surgery, Global Open, 2022
Background:. Keloids are disfiguring, scar-like lesions that are challenging to treat, with low response rates to current interventions and frequent recurrence.
Jennifer M. Hahn, BS, Kevin L. McFarland, MS, JD, Kelly A. Combs, BS, Heather M. Powell, PhD, Dorothy M. Supp, PhD   +4 more
doaj   +1 more source

Giant bilateral keloids of the ear lobule: Case report and brief review of literature

Journal of Family Medicine and Primary Care, 2017
Keloids are abnormal tissue response to cutaneous injury. They are benign fibrocollagenous growth that rise above the skin surface and extend beyond the borders of the original wound.
Satish K Ranjan, Aftab Ahmed, Viraat Harsh, Nawal K Jha   +3 more
doaj   +1 more source

Single-cell RNA sequencing reveals distinct immunology profiles in human keloid

Frontiers in Immunology, 2022
Keloids, characterized by skin fibrosis and excessive accumulation of extracellular matrix, remain a therapeutic challenge. In this study, we systematically capture the cellular composition of keloids by the single-cell RNA sequencing technique.
Cheng Feng, Mengjie Shan, Mengjie Shan, Yijun Xia, Yijun Xia, Zhi Zheng, Kai He, Yingxin Wei, Kexin Song, Tian Meng, Hao Liu, Yan Hao, Yan Hao, Zhengyun Liang, Zhengyun Liang, Youbin Wang, Yongsheng Huang   +16 more
doaj   +1 more source

Multiple Cytokines Elevated in Patients with Keloids: Is It an Indication of Auto-Inflammatory Disease?

, 2021
Ferdinand W Nangole,1 Kelsey Ouyang,2 Omu Anzala,3 Julius Ogengo,4 George W Agak2 1Department of Surgery, University of Nairobi, Nairobi, Kenya; 2Division of Dermatology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA; 3Institute ...
Agak GW, Ogengo J, Ouyang K, Anzala O, Nangole FW   +4 more
core  

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Do Mesenchymal Stem Cells Influence Keloid Recurrence?

Stem Cells and Cloning: Advances and Applications, 2022
Wanjala Ferdinand Nang’ole,1 Anzala Omu,2 Julius A Ogeng’o,3 George W Agak4 1Department of Surgery, University of Nairobi, Nairobi, Kenya; 2Kenya Aids Vaccine Institute, University of Nairobi, Nairobi, Kenya; 3Department of Human Anatomy, University of ...
Nang'ole WF, Omu A, Ogeng'o JA, Agak GW
doaj  

Dual‐Targeting Biomimetic Nanozymes Loaded Microneedle Patch Promotes Scarless Wound Healing Through Anti‐Inflammatory and Anti‐Fibrotic Effects

Advanced Science, EarlyView.
This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang, Jinwei Li, Shan Hua, Shengming Wu, Chenlong He, Yuan Zhu, Ming Yin, Han Zhou, Huawei Liu, Chika Hasegawa, Jun Lyu, Keyue Xiao, Hua Jiang, Yilong Wang, Yuxin Qian   +14 more
wiley   +1 more source