Results 91 to 100 of about 297,585 (279)

Integration of lipidomics and widely targeted metabolomics provides a comprehensive metabolic landscape of Poa pratensis under cadmium stress

BMC Plant Biology
Background Soil cadmium (Cd) contamination poses significant environmental challenges globally. Kentucky bluegrass is considered a viable plant for remediating Cd-contaminated soils due to its high tolerance to Cd and accumulation capacity.
Ting Cui, Yong Wang, Kuiju Niu, Chunxu Zhao, Huiling Ma   +4 more
doaj   +1 more source

USP30‐Mediated Deubiquitination of PEX5 Suppresses Pexophagy to Drive Tubular Injury in Diabetic Kidney Disease

Advanced Science, EarlyView.
USP30 accumulation in diabetic renal tubular epithelial cells deubiquitinates PEX5, suppresses pexophagy, and drives dysfunctional peroxisome accumulation and tubular injury. USP30 depletion restores PEX5 ubiquitination and pexophagy, improves peroxisomal function, and alleviates tubular damage, highlighting USP30 as a therapeutic target in diabetic ...
Jia Li, Chaoyang Hua, Guangpu Li, Furong Zhai, Jingjing Ren, Shaokang Pan, Qi Feng, Jianguo Wen, Dongwei Liu, Zhangsuo Liu, Jiayu Duan   +10 more
wiley   +1 more source

Kentucky 4-H Minimizes Barriers to STEM Education [PDF]

, 2018
Science, Technology, Engineering, and Math (STEM) programs are a national priority. The increase in the number of jobs that require a STEM-minded workforce raises the demand for education systems and communities to focus on fostering the development of ...
Noble, Rachel Elizabeth
core   +1 more source

Estimation of average daily traffic on local roads in Kentucky. [PDF]

FRT 201Kentucky Transportation Cabinet (KYTC) officials use annual average daily traffic (AADT) to estimate intersectionperformance across the state maintained highway system.
Staats, William, Green, Eric, University of Kentucky. College of Engineering, University of Kentucky Transportation Center, Souleyrette, Reginald R., Howell, Brian K.   +5 more
core   +1 more source

Encapsulated Leptin‐Producing Cells Facilitate Entrainment of Circadian Rhythms in Rodents and Nonhuman Primates

Advanced Science, EarlyView.
A clinically translatable cell line can be engineered to produce leptin, encapsulated in biomaterial and safely implanted to produce and deliver the metabolic regulating protein within the body. Implantation of these encapsulated cells decreases the time it takes for mice and non‐human primates to adjust to circadian disruptions similar to those ...
Samantha T. Fleury, Xuanyi Lin, Peter D. Rios, Christopher Olker, Eun Joo Song, Alejandra Cobos Perez, Cody Fell, Daisy Lopez, Ira Joshi, Hafsa Nasir, Cecelia Curtis, Danna Muringi, Kaiyuan Wang, José Oberholzer, Fred W. Turek, Isaac B. Hilton, Jonathan Rivnay, Martha Hotz Vitaterna, Omid Veiseh   +18 more
wiley   +1 more source

Validating A Kentucky Wetland Rapid Assessment Method For Forested Riverine Wetlands Using Vegetation, Bird Surveys, And Landscape Analysis [PDF]

, 2015
Within the last two centuries, Kentucky has undergone wetland losses exceeding 80 percent (approximately 500,000 hectares). As a response to these losses, the Kentucky Division of Water (KDOW) and Eastern Kentucky University (EKU) developed the Kentucky ...
Polascik, JohnRyan Andrew
core   +1 more source

Nicotinamide Metabolism Constrains Memory CD8+ T Cell Formation Through a Putative HS1BP3‐SIRT1‐FOXO3‐BCL6 Axis

Advanced Science, EarlyView.
ABSTRACT Memory T cells exhibit long‐term persistence, a defining feature that underpins durable clinical responses to adoptive immunotherapies. The mechanisms that integrate metabolic cues with transcriptional control of memory fate remain undetermined. Here, we identify HS1‐binding protein 3 (HS1BP3) is preferentially expressed in memory CD8+ T cells.
Siyang Wang, Xiaoqian Fan, Yifan Huang, Chang Yao, Jixing Fan, Yu Ping, Xuan Zhao, Congcong Li, Chunyi Shen, Jiqi Shan, Jinyan Liu, Shengdian Wang, Zhen Zhang, Yi Zhang   +13 more
wiley   +1 more source

Measuring the value of Kentucky vehicle enforcement activities. [PDF]

SPR-08-332-07-1FThe responsibility for monitoring commercial vehicles on Kentucky\u2019s roadways and enforcing the applicable laws and regulations falls primarily on Kentucky Vehicle Enforcement (KVE).
Wallace, Candice Y., Pigman, Jerry G., University of Kentucky Transportation Center, Crabtree, Joseph D., Walton, Jennifer R.   +4 more
core  

An RNA‐Binding Protein RBMS1 Promotes Endothelial Cell Autophagy to Maintain Vascular Homeostasis and Suppress Deep Vein Thrombosis

Advanced Science, EarlyView.
RBMS1, an RNA‐binding protein, restores vascular endothelial homeostasis by enhancing ATG3‐mediated autophagy, thereby attenuating thrombus formation and suggesting a potential avenue for further therapeutic exploration in DVT. ABSTRACT Deep vein thrombosis (DVT) is a prevalent vascular disorder characterized by aberrant coagulation within the deep ...
Chu Chu, Xinkui Liu, Nannan Fan, Xiaoyan Yu, Qiaoqiao Han, Yunhong Zhang, Wei Li, Yongqing Cai, Miaomiao Zhou, Fang Li, Feifei Shi, Zhen Zhang, Bin Wang, Xia Li   +13 more
wiley   +1 more source

Population Distribution and Abundance of the Blackfin Sucker (Thoburnia atripinnis) in the Upper Barren River System, Kentucky and Tennessee. [PDF]

, 2013
The blackfin sucker (Thoburnia atripinnis) is a relatively small species of fish (~155mm) endemic to the headwaters of the Barren River System (UBR) in Kentucky and Tennessee.
Stringfield, Cory Daniel
core   +1 more source