Results 81 to 90 of about 297,585 (279)
USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis
Advanced Science, EarlyView.This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui +5 more
wiley +1 more source
EFFECTS OF CHLORIDE SALINITY ON NON-ENZYMATIC ANTIOXIDANT ACTIVITY, PROLINE AND MALONDIALDEHYDE CONTENT IN THREE FLUE-CURED CULTIVARS OF TOBACCO [PDF]
Journal of Plant Development, 2014 High salinity causes ion poisoning and subsequent oxidative stress. During oxidative ion poisoning, non-enzymatic defense systems such as carotenoids, phenols and flavonoids are activated.
Akbar NORASTEHNIA +3 more
doaj
Ciprofloxacin-Resistant Salmonella enterica Serovar Kentucky in Canada
Emerging Infectious Diseases, 2013 We report emergence of ciprofloxacin-resistant Salmonella enterica serovar Kentucky in Canada during 2003–2009. All isolates had similar macrorestriction patterns and were multilocus sequence type ST198, which has been observed in Europe and Africa ...
Michael R. Mulvey +14 more
doaj +1 more source
Advanced Science, EarlyView.Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu +12 more
wiley +1 more source
Courting Toyota, Selling Kentucky: Conflict and Relationship Building in the Establishment of Toyota Motor Manufacturing of Kentucky, 1984-1989 [PDF]
, 2011 This study is an examination of the social, economic, and governmental factors that surrounded the establishment of Toyota Motor Corporation\u27s first wholly owned automobile plant in the United States.
Bailey, Eric Shea
core +1 more source
PENGARUH BRAND IMAGE DAN HARGA TERHADAP KEPUTUSAN PEMBELIAN KONSUMEN PADA PRODUK CHICKEN KFC
Almana: Jurnal Manajemen dan Bisnis, 2019 Teknik analisis data yang digunakan adalah analisis jalur. Metode yang digunakan dalam penelitian ini adalah metode deskriptif dan verifikatif. Sampel diambil dengan metode accidental sampling. Ukuran sampel sebanyak 88 orang.
Yanuar Firmanto
doaj +1 more source
Advanced Science, EarlyView.Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae +5 more
wiley +1 more source
Scope of Homelessness in Kentucky [PDF]
, 2022 This paper is based on a data project that pulled together publicly available data from several sources to examine the scope of homelessness in the Commonwealth of Kentucky.
Catron, Shannon Elyse
core
Advanced Science, EarlyView.Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li +21 more
wiley +1 more source