Results 71 to 80 of about 297,585 (279)

Identifying and Treating Incarcerated Women Experiencing Substance Use Disorders: A Review

Substance Abuse and Rehabilitation, 2023
Michele Staton,1,2 Martha Tillson,2 Mary M Levi,3 Megan Dickson,1,2 Matt Webster,1,2 Carl Leukefeld1,2 1Department of Behavioral Science, University of Kentucky, Lexington, KY, USA; 2Center on Drug and Alcohol Research, University of Kentucky, Lexington,
Staton M, Tillson M, Levi MM, Dickson M, Webster M, Leukefeld C   +5 more
doaj  

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood–Brain Barrier Failure in Cerebral Amyloid Angiopathy

Advanced Science, EarlyView.
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng, Qiang Li, Haiyang Luo, Yapei Yuan, Na Zhang, Yongting Lu, Suying Duan, Jieshi Zhong, Hang Zhang, Chenyang Liu, Yaochong Zhang, Wenzhuo Zhao, Yaxuan Song, Tuo Wang, Si Yan, Yapeng Li, Han Liu, Yuan Gao, Zongping Xia, Yuming Xu   +19 more
wiley   +1 more source

2009 safety belt usage survey in Kentucky. [PDF]

The objective of this study was to establish 2009 safety belt and child safety seat usage rates in Kentucky. The 2009 survey continues to document the results after enactment of original "secondary enforcement" statewide mandatory safety belt law in 1994
Green, Eric R., University of Kentucky Transportation Center, Agent, Kenneth R.   +2 more
core  

ANGPTL4 Exacerbates Renal Injury in Diabetic Kidney Disease by Impairing Podocyte Lipophagy via Compromised Lysosomal Degradative Function

Advanced Science, EarlyView.
In diabetic kidney disease, elevated podocyte ANGPTL4 is linked to reduced TFEB nuclear localization and compromised lysosomal degradative function. These changes impair podocyte lipophagy and promote lipid‐droplet accumulation and podocyte injury, which may contribute to renal injury progression.
Xiaojing Liu, Shimin Jiang, Zhenkun Yang, Shunlai Shang, Jiayi Li, Guming Zou, Cheng Zhou, Wenge Li   +7 more
wiley   +1 more source

Supplemental invasion of Salmonella from the perspective of Salmonella enterica serovars Kentucky and Typhimurium

BMC Microbiology, 2017
Background Critical to the development of Salmonellosis in humans is the interaction of the bacterium with the epithelial lining of the gastrointestinal tract. Traditional scientific reasoning held type III secretion system (T3SS) as the virulence factor
Kevin Howe, Sanaz Salehi, R. Hartford Bailey, John P. Brooks, Robert Wills, Mark L. Lawrence, Attila Karsi   +6 more
doaj   +1 more source

Matrix Stiffness Enhances Odontogenic Differentiation of DPSCs through Membrane Curvature Protein Baiap2‐Modulated Exosome Release

Advanced Science, EarlyView.
Matrix stiffness softening is identified as a previously underappreciated feature in deep caries. Higher stiffness drives exosome release in dental pulp stem cells through a coordinated mechanism involving PI3K–AKT‐regulated Baiap2 and kinesin‐1, thereby promoting odontogenic differentiation.
Bilun Jin, Shaojie Dong, Yue Jia, Zhao Xu, Peiqi Liu, Zhaojing Ding, Yuxin Liao, Rui Zou, Jinsong Hu, Bo Cheng, Lin Niu   +10 more
wiley   +1 more source

Ergonomics Programs In Kentucky\u27s Nursing Homes [PDF]

, 2017
This study sought to determine how many nursing homes had implemented ergonomics programs, and how closely these programs followed the NIOSH/OSHA model.
Stumbo, David
core   +1 more source

Persistent Colonization of Ciprofloxacin-Resistant and Extended-Spectrum β-Lactamase (ESBL)-Producing Salmonella enterica Serovar Kentucky ST198 in a Patient with Inflammatory Bowel Disease

Infection and Drug Resistance
Yue Jiang,1,2,* Huilin Yang,3,* Zhen-Yu Wang,1,2 Da-Chuan Lin,4 Xinan Jiao,1,2 Yunlong Hu,3,4 Jing Wang1,2 1Jiangsu Key Laboratory of Zoonosis, Yangzhou University, Yangzhou, 225009, People’s Republic of China; 2Key Laboratory of Prevention and ...
Jiang Y, Yang H, Wang ZY, Lin DC, Jiao X, Hu Y, Wang J   +6 more
doaj  

Access management implementation in Kentucky technical support document and status report. [PDF]

KTC-08-05/SPR290-05-2FThis report describes the efforts of the Kentucky Transportation Cabinet's Access Management implementation Task Force. The task force was established in May 2004 and was charged with the responsibility of reviewing and refining the
House, Barry, University of Kentucky Transportation Center   +1 more
core  

Analysis of traffic crash data in Kentucky (2011\u20132015).

This report documents an analysis of traffic crash data in Kentucky for the years of 2011 through 2015. A primary objective of this study was to determine average crash statistics for Kentucky highways. Rates were calculated for various types of highways
Green, Eric R., Fields, Michael A., Pigman, Jerry G., University of Kentucky Transportation Center, Agent, Kenneth R.   +4 more
core   +1 more source