Results 131 to 140 of about 3,241,173 (293)

Hiperqueratose epidermolítica em gêmeas monozigóticas: relato de caso e revisão de literatura. [PDF]

open access: yes, 2007
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Sens, Mariana Mazzochi
core  

Synergistic Effects of Cosolvents on the Dissolution of Wool Keratin Using Ionic Liquids

open access: yes, 2016
Keratin, regenerated from wool fibers, is widely used in the textile and medicine fields. In this work, a series of synthesized 1-butyl-3-methylimidazolium-based ionic liquids (IL) were used to dissolve wool keratin.
Zhang, Xiangping   +5 more
core   +1 more source

Absence of keratin 8 or 18 promotes antimitochondrial autoantibody formation in aging male mice [PDF]

open access: yes, 2015
Human mutations in keratin 8 (K8) and keratin 18 (K18), the intermediate filament proteins of hepatocytes, predispose to several liver diseases. K8‐null mice develop chronic liver injury and fragile hepatocytes, dysfunctional mitochondria, and Th2‐type ...
Zhang, Linxing   +8 more
core   +1 more source

Transfersomes with core and surface‐loaded NF‐κB p65 siRNA for enhanced transdermal transfection and effective treatment of psoriasis

open access: yesBMEMat, EarlyView.
TCPL, a transfersome with Tween 80 and PEI, enables efficient transdermal siNF‐κB delivery, resolving PEI's toxicity issue. It promotes lysosomal escape and effective transfection, silences NF‐κB, modulates immunity, and inhibits angiogenesis, alleviating psoriasis. With good biocompatibility, TCPL holds strong clinical translation potential. Schematic
Hui Xing   +6 more
wiley   +1 more source

Molecular Modeling of Pathogenic Mutations in the Keratin 1B Domain

open access: yes, 2020
Keratin intermediate filaments constitute the primary cytoskeletal component of epithelial cells. Numerous human disease phenotypes related to keratin mutation remain mechanistically elusive.
Alexander J. Hinbest   +3 more
core   +1 more source

Diet of bird‐like troodontid dinosaurs: synthesis of a contentious clade

open access: yesBiological Reviews, EarlyView.
ABSTRACT Troodontidae is a clade of small‐to medium‐sized maniraptoran theropods that mainly lived in Laurasia (modern Asia, North America and Europe) during the Jurassic and Cretaceous periods and are believed to have had a variety of diets. The uniqueness of troodontid teeth suggests that they diverged from the typical flesh‐based diet of non‐avian ...
Yui Chi Fan   +2 more
wiley   +1 more source

Producing keratin hydrolysates from sheep wool [PDF]

open access: yes, 2012
Manuscript describes producing keratin hydrolysate from sheep wool through two-stage technology whose principle consists in first having wool processed in an alkaline environment during the first stage, and then effecting hydrolysis in the second stage ...
Svoboda (FT), Petr   +2 more
core  

Protein hydrolysates in cell culture: Toward multi‐omics characterization

open access: yesBiotechnology Progress, EarlyView.
While protein hydrolysates are widely used in cell culture applications, they remain undefined and variable products. Multi‐omic characterization evaluating composition and function can transition hydrolysates toward semi‐defined media components.
Michelle Combe   +3 more
wiley   +1 more source

Keratin-Nylon 6 engineered microbeads for adsorption of Th (IV) ions from liquid effluents

open access: yes, 2017
The applicability of novel porous microbeads (average diameter of about 2.0 mm) of α-keratin engineered with Nylon 6, have been investigated for the adsorption of radioactive and non-biodegradable Th (IV) ions from the effluents.
L Khurana (13547173)   +3 more
core  

Prediction of Acute Liver Injury Trajectory in Patients Following Acetaminophen Overdose: A Multibiomarker Machine Learning Proof‐of‐Concept Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Clinical translation of novel therapies can be hindered by heterogeneity‐driven sample size inflation in late‐stage trials. In acetaminophen‐induced liver injury (APAP DILI), many patients recover spontaneously, diluting investigational drug efficacy signals.
Chris Humphries   +8 more
wiley   +1 more source

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