Results 91 to 100 of about 3,543,538 (259)

Age and the means of bypassing stasis are determinants of the intrinsic subtypes of immortalized human mammary epithelial cells

open access: yesFrontiers in Cell and Developmental Biology, 2015
Based on molecular features, breast cancers are grouped into intrinsic subtypes that have different prognoses and therapeutic response profiles. With increasing age, breast cancer incidence increases, with hormone receptor-positive and other luminal-like
Jonathan K Lee   +4 more
doaj   +1 more source

Osteoblast behaviour on keratin modified titanium surface

open access: yes, 2023
INTRODUCTION: Surface modification of titanium by coating with natural bioactive polymers, has been suggested as a means to improve osseointegration in dental implantology applications.
Ranjit, Eliza   +2 more
core   +1 more source

Selenium Nanomaterials for Wound Healing: Synergistic Strategies from Anti‐Infection to Tissue Regeneration

open access: yesAdvanced NanoBiomed Research, EarlyView.
Selenium nanoparticles (SeNPs) are emerging as multifunctional platforms for wound healing, integrating antimicrobial, anti‐inflammatory, and proregenerative activities. This review summarises key mechanisms and recent advances in SeNP‐enabled composite dressings, immunomodulatory nanocomposites, microenvironment‐responsive hydrogels, photothermal and ...
Yangxia Chen   +10 more
wiley   +1 more source

Actomyosin forces trigger a conformational change in desmoplakin within desmosomes

open access: yesNature Communications
Desmosomes are essential cell-cell adhesion organelles that enable tension-prone tissues, like the skin and heart, to withstand mechanical stress.
Yinchen Dong   +6 more
doaj   +1 more source

Sheep Horn Development Revealed by Multi‐Tissue and Cross‐Species Transcriptomic Analysis

open access: yesAnimal Research and One Health, EarlyView.
Multi‐tissue and cross‐species transcriptomics with allele‐specific expression show sheep horns are a composite organ integrating epidermal and osteogenic programs. Conserved horn gene modules and cis‐regulatory variation fine‐tune expression networks underlying horn development and size (small scurs vs. large spiral horns).
Hao Li   +10 more
wiley   +1 more source

Keratin Filaments in the Epithelial Cells of Circumvallate Papillae

open access: yes, 1988
P(論文)Keratin filaments of epithelial cells of both the dorsal surface and the trench wall in the circumvallate papillae were studied by conventional electron microscopy and by immunohisto- chemistry using antikeratin antibodies.
小原, 伸子   +5 more
core   +1 more source

In-situ development of self-defensive antibacterial biomaterials: phenol-g-keratin-EC based bio-composites with characteristics for biomedical applications [PDF]

open access: yes, 2015
Recently, the development of highly inspired biomaterials with multi-functional characteristics has gained considerable attention, especially in biomedical, and other health-related areas of the modern world.
Kyazze, G.   +9 more
core   +1 more source

Transfersomes with core and surface‐loaded NF‐κB p65 siRNA for enhanced transdermal transfection and effective treatment of psoriasis

open access: yesBMEMat, EarlyView.
TCPL, a transfersome with Tween 80 and PEI, enables efficient transdermal siNF‐κB delivery, resolving PEI's toxicity issue. It promotes lysosomal escape and effective transfection, silences NF‐κB, modulates immunity, and inhibits angiogenesis, alleviating psoriasis. With good biocompatibility, TCPL holds strong clinical translation potential. Schematic
Hui Xing   +6 more
wiley   +1 more source

HERC4 downregulates KRT19 to promote lung adenocarcinoma, migration, invasion and EMT

open access: yesTranslational Oncology
Background: Metastasis is a major cause of treatment failure and poor prognosis in lung adenocarcinoma (LUAD). Epithelial-mesenchymal transition (EMT) plays a crucial role in promoting LUAD metastasis.
Hao-Jia Sun   +4 more
doaj   +1 more source

The New Keratin Nomenclature

open access: yes, 2006
When the first nomenclature of the keratin protein family was published over 20 years ago, only 19 keratins were thought to exist. Sequencing of the human genome has now revealed that there are 54 keratin genes.
Porter, Rebecca M.
core   +1 more source

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