Results 31 to 40 of about 55,822 (247)
Keratin 19 as a key molecule in progression of human hepatocellular carcinomas through invasion and angiogenesis. [PDF]
BMC Cancer, 2016 Keratin (K) 19-positive hepatocellular carcinoma (HCC) is well known to have a higher malignant potential than K19-negative HCC: However, the molecular mechanisms involved in K19-mediated progression of HCC remain unclear. We attempted to clarify whether K19 directly affects cell survival and invasiveness in association with cellular senescence or ...
Takano M +8 more
europepmc +3 more sources
Biomolecules, 2021 Congenital PAX6-aniridia is a rare panocular disease resulting from limbal stem cell deficiency. In PAX6-aniridia, the downregulation of the retinol-metabolizing enzymes ADH7 (All-trans-retinol dehydrogenase 7) and ALDH1A1/A3 (Retinal dehydrogenase 1 ...
Lorenz Latta +9 more
doaj +1 more source
Keratin 19 protein expression is an independent predictor of survival in human hepatocellular carcinoma [PDF]
European Journal of Gastroenterology & Hepatology, 2015 We aimed to assess the clinicopathological relevance and prognostic significance of expression of the hepatic progenitor cell markers keratin 19 (K19), epithelial cell adhesion molecule (EpCAM) and CD117 (c-KIT) in a White series of hepatocellular carcinoma (HCC).We evaluated the immunohistochemical expression of K19, EpCAM and CD117 in 89 surgical ...
Fatourou E +10 more
openaire +4 more sources
Chinese Journal of Traumatology, 2017 Purpose: To further study the mechanism of epithelization on the fascia side of the flap after surgical incision and the treatment of the negative pressure therapy.
Jiao-Yun Dong +3 more
doaj +1 more source
The Type I Keratin 19 Possesses Distinct and Context-dependent Assembly Properties [PDF]
Journal of Biological Chemistry, 1998 Keratins (K), the cytoplasmic intermediate filament (IF) proteins of epithelial cells, are encoded by a multigene family and expressed in a tissue- and differentiation-specific manner. In human skin, keratinocytes of the basal layer of epidermis and the outer root sheath of hair follicles express K5 and K14 as their main keratins. A small subpopulation
J, Fradette +3 more
openaire +2 more sources
Clinical and Prognostic Significances of Cytokeratin 19 and KIT Expression in Surgically Resectable Pancreatic Neuroendocrine Tumors [PDF]
Journal of Pathology and Translational Medicine, 2015 Background: Pancreatic neuroendocrine tumors (PanNETs) are malignant endocrine neoplasms that present diverse clinical behaviors. Therefore, identification of biomarkers of PanNETs is important for stratification of the prognosis of PanNET patients ...
Eun-Mi Son +6 more
doaj +1 more source
Influences of Desmin and Keratin 19 on Passive Biomechanical Properties of Mouse Skeletal Muscle [PDF]
Journal of Biomedicine and Biotechnology, 2012 In skeletal muscle fibers, forces must be transmitted between the plasma membrane and the intracellular contractile lattice, and within this lattice between adjacent myofibrils. Based on their prevalence, biomechanical properties and localization, desmin and keratin intermediate filaments (IFs) are likely to participate in structural connectivity and ...
Shah, Sameer B. +4 more
openaire +2 more sources
Chicken keratin‐19: Cloning of cDNA and analysis of expression in the chicken embryonic gut [PDF]
Development, Growth & Differentiation, 1997 From many recent studies, it has been argued that keratins (cytokeratins) play important roles in the morphogenesis and differentiation of organ development. To learn the role of keratin in digestive tract development, a cDNA of the chicken homolog of keratin‐19 (GK‐19) was cloned and its expression pattern was analyzed in the digestive tract of ...
K, Sato, S, Yasugi
openaire +2 more sources
Heterogeneity of estrogen receptor expression in circulating tumor cells from metastatic breast cancer patients. [PDF]
PLoS ONE, 2013 BACKGROUND: Endocrine treatment is the most preferable systemic treatment in metastatic breast cancer patients that have had an estrogen receptor (ER) positive primary tumor or metastatic lesions, however, approximately 20% of these patients do not ...
Anna Babayan +5 more
doaj +1 more source
Serum keratin 19 (
Liver International, 2022 AbstractBackground and AimsUp to 30% of patients with severe alcoholic hepatitis (sAH) die within 3 months of presentation. The degree of ductular reaction, characterized by accumulation of biliary and liver progenitor cells, confers a poor prognosis.
Stephen Rahul Atkinson +8 more
openaire +3 more sources