HNRNPK is retained in the cytoplasm by Keratin 19 to stabilize target mRNAs [PDF]
, 2022 Abstract Heterogeneous nuclear ribonucleoprotein K (HNRNPK) regulates pre-mRNA processing and long non-coding RNA localization in the nucleus. It was previously shown that shuttling of HNRNPK to the cytoplasm promotes cell proliferation and cancer metastasis. However, the mechanism of HNRNPK cytoplasmic localization, its cytoplasmic RNA
Arwa Fallatah +10 more
openaire +1 more source
An Integrative Bioinformatic Analysis for Keratinase Detection in Marine-Derived Streptomyces
Marine Drugs, 2021 Keratinases present promising biotechnological applications, due to their ability to degrade keratin. Streptomyces appears as one of the main sources of these enzymes, but complete genome sequences of keratinolytic bacteria are still limited.
Ricardo Valencia +5 more
doaj +1 more source
Silver Sulfadiazine's Effect on Keratin-19 Expression as Stem Cell Marker in Burn Wound Healing
BioMedicine, 2020 Background Burn wounds are one of the causes of cutaneous injury that involve both epidermal and dermal layers of skin. Silver sulfadiazine (SSD) has been widely used to treat burn wounds, however recent studies have found the treatment to have some ...
Dewi Sukmawati +2 more
semanticscholar +1 more source
Case Reports in Hepatology, 2020 Objective. Under normal conditions, adult hepatocytes express only keratin-8 (K8) and keratin-18 (K18), whereas cholangiocytes also express K19. In this study, we delineate the pattern of normal time-course changes in serum K19 and K18 levels after liver
Cristina Macía +7 more
doaj +1 more source
Two mechanisms regulate keratin K15 expression in keratinocytes:role of PKC/AP-1 and FOXM1 mediated signalling [PDF]
, 2012 Background: Keratin 15 (K15) is a type I keratin that is used as a marker of stem cells. Its expression is restricted to the basal layer of stratified epithelia, and the bulge in hair follicles.
Ahmad Waseem (155362) +30 more
core +1 more source
The molecular genetic analysis of the expanding pachyonychia congenita case collection [PDF]
, 2014 BackgroundPachyonychia congenita (PC) is a rare autosomal dominant keratinizing disorder characterized by severe, painful, palmoplantar keratoderma (PPK) and nail dystrophy, often accompanied by oral leukokeratosis, cysts and follicular keratosis.
Wilson, N. J. +9 more
core +1 more source
The Adjuvant Therapy Influence upon Micrometastasis in Bone Marrow Aspiration and Detection of Relapse Rate in Breast Cancer Patients Follow up [PDF]
International Journal of Hematology-Oncology and Stem Cell Research, 2010 "nIntroduction: Breast cancers in the early phase frequently undergo distant metastasis and survival of patients is greatly dependent on distant metastasis.
Mozafar Aznab +4 more
doaj +2 more sources
An ex vivo comparison of the tensile strengthening properties of protein derivatives on damaged hair [PDF]
, 2015 Conventional conditioning agents, cationic surfactants and polymers, are often limited in their ability to repair and strengthen the hair fibre, while protein-derived actives have been found to enhance the tensile strength of damaged hair.
Daniels, Gabriela +3 more
core +5 more sources
The Tumor Markers Tpa, Tps, Tpa and Cyfra 21–1 React Differently with the Keratins 8, 18 and 19
The International Journal of Biological Markers, 1994 The commercially available tumor marker tests TPA, TPS, TPA CYK and CYFRA 21–1 react with simple epithelium keratins. From clinical studies it can be deduced that the pattern of keratin recognition must be different for each of these tests.
H. Bodenmüller +3 more
doaj +1 more source
Blackcurrant Extract with Phytoestrogen Activity Alleviates Hair Loss in Ovariectomized Rats
Molecules, 2019 Ancocyanin-rich blackcurrant extract (BCE) has phytoestrogen activity; however, its effect on hair follicles is unknown. Additionally, hair loss is known to occur during menopause in women owing to decreased estrogen secretion.
Naoki Nanashima, Kayo Horie
doaj +1 more source