Results 211 to 220 of about 62,676,716 (288)

Prediction of Acute Liver Injury Trajectory in Patients Following Acetaminophen Overdose: A Multibiomarker Machine Learning Proof‐of‐Concept Study

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 5, Page 1326-1337, November 2026.
Clinical translation of novel therapies can be hindered by heterogeneity‐driven sample size inflation in late‐stage trials. In acetaminophen‐induced liver injury (APAP DILI), many patients recover spontaneously, diluting investigational drug efficacy signals.
Chris Humphries   +8 more
wiley   +1 more source

Lymph Node Regression Improves Prognostic Stratification in Esophageal Squamous Cell Carcinoma Receiving Neoadjuvant Chemoimmunotherapy: A Multicenter Retrospective Cohort Study

open access: yesMedComm, Volume 7, Issue 11, November 2026.
Pathological lymph node regression grading predicts survival after neoadjuvant chemoimmunotherapy. (A) Schematic illustration of the novel five‐tier lymph node regression grading (LNRG) system and representative histopathological images. LNRG 1–4 were defined as follows: LNRG 1, no viable tumor cells observed within the tumor bed; LNRG 2, viable tumor ...
Jian Zheng   +15 more
wiley   +1 more source

Impact of Dupilumab Therapy on Skin Barrier Function in Patients With Moderate‐to‐Severe Atopic Dermatitis: A Phase IV, Non‐Randomized, Open‐Label, Parallel‐Group Clinical Study

open access: yesMedComm, Volume 7, Issue 11, November 2026.
This 16‑week study assessed impact of dupilumab on skin barrier function in patients with moderate‑to‑severe atopic dermatitis (AD). Tape‑stripped stratum corneum samples for multi‑omic profiling, alongside transepidermal water loss measurements, were collected from lesional/non‑lesional AD skin and healthy controls at seven time points.
Taoming Liu   +21 more
wiley   +1 more source

Submandibular odontogenic choristoma in a Boer goat

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract Submandibular odontogenic choristoma is a rare anomaly in both human and veterinary medicine. A case is described here in a Boer goat used for show, from which the benign growth was surgically removed without complication. This case documents the clinical presentation, diagnostic imaging and histopathology of this anomaly.
Steven E. Edmonds   +3 more
wiley   +1 more source

Characterisation of human hair follicle development

open access: yesJournal of Anatomy, Volume 249, Issue 5, Page 1033-1049, November 2026.
Schematic of hair follicle development in human skin. Hair follicle primordia of similar sizes, but different densities, are laid out across the skin. The distinction between terminal and vellus hair sites is not obvious at early stages of hair follicle development.
Zoe R. Sudderick   +4 more
wiley   +1 more source

Proteome of Human Scalp Hair Follicles. [PDF]

open access: yesCureus
Hegde A   +3 more
europepmc   +1 more source

Design Considerations for Polymer–Deep Eutectic Solvent Hybrid Systems for Transdermal Drug Delivery

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 40, October 20, 2026.
Deep eutectic solvents (DESs) act as tunable, green excipients that modulate polymer structure–property relationships to enhance drug solubility, skin permeation, stability, and controlled release. Through hydrogen‐bond interactions, DES–polymer hybrid systems enable improved transdermal performance, offering a rational, design‐driven platform for ...
Madhavi Kailas Kapale   +3 more
wiley   +1 more source

Porous Poly(ε‐Caprolactone)/Keratin Composite Scaffolds: Structural Features, Degradation Behavior and Cell‐Material Interactions

open access: yesJournal of Applied Polymer Science, Volume 143, Issue 40, October 20, 2026.
ABSTRACT Porous scaffolds based on pure poly(ε‐caprolactone) (PCL) and on biocomposite made of PCL and feather‐extracted β‐keratin (FK) were fabricated by salt‐leaching method. FK was incorporated into PCL to address the limited bioactivity and hydrophobic nature of PCL, with the aim of improving cell–material interactions for bone tissue engineering ...
Gianluca Rinaldi   +6 more
wiley   +1 more source

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