Results 211 to 220 of about 62,676,716 (288)
Clinical translation of novel therapies can be hindered by heterogeneity‐driven sample size inflation in late‐stage trials. In acetaminophen‐induced liver injury (APAP DILI), many patients recover spontaneously, diluting investigational drug efficacy signals.
Chris Humphries +8 more
wiley +1 more source
Extreme Biomimetics: Achievements and Fundamental Challenges for the Future. [PDF]
Ehrlich H, Jesionowski T.
europepmc +1 more source
Pathological lymph node regression grading predicts survival after neoadjuvant chemoimmunotherapy. (A) Schematic illustration of the novel five‐tier lymph node regression grading (LNRG) system and representative histopathological images. LNRG 1–4 were defined as follows: LNRG 1, no viable tumor cells observed within the tumor bed; LNRG 2, viable tumor ...
Jian Zheng +15 more
wiley +1 more source
This 16‑week study assessed impact of dupilumab on skin barrier function in patients with moderate‑to‑severe atopic dermatitis (AD). Tape‑stripped stratum corneum samples for multi‑omic profiling, alongside transepidermal water loss measurements, were collected from lesional/non‑lesional AD skin and healthy controls at seven time points.
Taoming Liu +21 more
wiley +1 more source
Sarcomatoid Squamous Cell Carcinoma and Its Mimics: A Meta-Analysis of Institutional Cases and Published Reports. [PDF]
Kiratikanon S +3 more
europepmc +1 more source
Submandibular odontogenic choristoma in a Boer goat
Abstract Submandibular odontogenic choristoma is a rare anomaly in both human and veterinary medicine. A case is described here in a Boer goat used for show, from which the benign growth was surgically removed without complication. This case documents the clinical presentation, diagnostic imaging and histopathology of this anomaly.
Steven E. Edmonds +3 more
wiley +1 more source
Characterisation of human hair follicle development
Schematic of hair follicle development in human skin. Hair follicle primordia of similar sizes, but different densities, are laid out across the skin. The distinction between terminal and vellus hair sites is not obvious at early stages of hair follicle development.
Zoe R. Sudderick +4 more
wiley +1 more source
Design Considerations for Polymer–Deep Eutectic Solvent Hybrid Systems for Transdermal Drug Delivery
Deep eutectic solvents (DESs) act as tunable, green excipients that modulate polymer structure–property relationships to enhance drug solubility, skin permeation, stability, and controlled release. Through hydrogen‐bond interactions, DES–polymer hybrid systems enable improved transdermal performance, offering a rational, design‐driven platform for ...
Madhavi Kailas Kapale +3 more
wiley +1 more source
ABSTRACT Porous scaffolds based on pure poly(ε‐caprolactone) (PCL) and on biocomposite made of PCL and feather‐extracted β‐keratin (FK) were fabricated by salt‐leaching method. FK was incorporated into PCL to address the limited bioactivity and hydrophobic nature of PCL, with the aim of improving cell–material interactions for bone tissue engineering ...
Gianluca Rinaldi +6 more
wiley +1 more source

