Results 221 to 230 of about 62,676,716 (288)
This work explores the use of various fillers, including eggshell powder, feather meal, peanut hulls, and sawdust to reinforce a base binder GFS90 (comprised of 90 wt.% sulfur, 5 wt.% chicken fat, and 5 wt.% sunflower oil). The resulting composites showed impressive compressive strengths ranging from 15.3 to 36.2 MPa, making them a potential ...
Bárbara G. S. Guinati +5 more
wiley +1 more source
Role of POU4F3 in the Diagnosis of Cutaneous Follicular Tumors. [PDF]
Gerber AA, Hosler GA, Hoang MP.
europepmc +1 more source
Deer Antler δ18O Records Desalination in Israel's Water Supply
ABSTRACT Rationale Stable oxygen isotope ratios (δ¹⁸O) in mammalian tissues are widely used to reconstruct past climates, seasonal patterns, and animal origins. These analyses assume that animals drink local rainwater—an assumption now challenged by large‐scale anthropogenic water management.
Corrin Laposki +3 more
wiley +1 more source
Loss of function of <i>ALDH3B2</i> transdifferentiates human pancreatic duct cells into β-like cells. [PDF]
Li J +15 more
europepmc +1 more source
Myxoglucamid A – ein neuartiges, aus Myxobakterien isoliertes Glykolipopeptid – wurde erstmals totalsynthetisch hergestellt. Mittels aktivitätsbasierter Proteinprofilierung (ABPP) wurde die Aldo‐Keto‐Reduktase 1C3 (AKR1C3) als primäres Zielprotein in menschlichen Zellen identifiziert.
Thomas Siemon +9 more
wiley +1 more source
Molecular Evidence for <i>KRT6A</i>-Associated Pachyonychia Congenita Tarda with Onset at Age 53. [PDF]
Xu Z, Bi L, Wang Z, Sheng Y, Cui Y.
europepmc +1 more source
Myxoglucamide A—a novel glycolipopeptide isolated from myxobacteria—was synthesized, and activity‐based protein profiling identified aldo‐keto reductase 1C3 (AKR1C3) as its main target in human cells. Structure‐activity relationship studies, together with biophysical characterization and X‐ray crystallography, elucidated the structural basis of AKR1C3 ...
Thomas Siemon +9 more
wiley +1 more source
Palmoplantar Keratoderma: A Mechanism-Based Disease Classification. [PDF]
Liu JW +5 more
europepmc +1 more source
TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang +11 more
wiley +1 more source
Canine Tear Proteomics: A New Frontier in Veterinary Ophthalmology. [PDF]
D'Agostino AL +5 more
europepmc +1 more source

