Results 61 to 70 of about 139,965 (339)
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Effects of keratin filaments on ERK signaling during Fas-induced death of cervical cancer (HeLa) cells [PDF]
, 2014 Survival of cancer cells is influenced by a variety of factors, including physical elements such as keratin filaments. We know HeLa cells containing or lacking keratin 8/18 intermediate filaments (K+ and K- cells, respectively) are more sensitive to the ...
Berger, Amanda
core +1 more source
Cellulose, Chitosan, and Keratin Composite Materials. Controlled Drug Release [PDF]
, 2015 A method was developed in which cellulose (CEL) and/or chitosan (CS) were added to keratin (KER) to enable [CEL/CS+KER] composites to have better mechanical strength and wider utilization.
Mututuvari, Tamutsiwa Moven +1 more
core +4 more sources
Deacetylation via SIRT2 prevents keratin-mutation-associated injury and keratin aggregation
JCI Insight, 2023 Keratin (K) and other intermediate filament (IF) protein mutations at conserved arginines disrupt keratin filaments into aggregates and cause human epidermolysis bullosa simplex (EBS; K14-R125C) or predispose to mouse liver injury (K18-R90C).
Jingyuan Sun +9 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan +4 more
wiley +1 more source
Periplakin, a novel component of cornified envelopes and desmosomes that belongs to the plakin family and forms complexes with envoplakin [PDF]
, 1997 The cornified envelope is a layer of transglutaminase cross-linked protein that is assembled under the plasma membrane of keratinocytes in the outermost layers of the epidermis.
Argos +57 more
core +2 more sources
Sustainable Management of Keratin Waste Biomass: Applications and Future Perspectives
Brazilian Archives of Biology and Technology, 2016 Keratin is a durable, fibrous protein which is mainly present in higher vertebrates (mammals, birds and reptiles) and humans epithelial cells. Food industry especially the meat market, slaughter house and wool industry produces million of tons of keratin
Swati Sharma, Arun Gupta
doaj +1 more source
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Advanced Functional Materials, EarlyView.Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan +4 more
wiley +1 more source
, 2016 Keratins comprise the type I and type II intermediate filament-forming proteins and occur primarily in epithelial cells. They are encoded by 54 evolutionarily conserved genes (28 type I, 26 type II) and regulated in a pairwise and tissue type-, differentiation-, and context-dependent manner.
Fengrong Wang +2 more
openaire +3 more sources
Keratin-Based Composite Bioactive Films and Their Preservative Effects on Cherry Tomato
Molecules, 2022 In this study, keratins were extracted from pig nail waste through the reduction method using L-cysteine as a reductant. Curcumin was successively incorporated in a mixed solution including keratin, gelatin, and glycerin to prepare different kinds of ...
Lanlan Wei +9 more
doaj +1 more source