Results 61 to 70 of about 85,880 (306)
Advanced Healthcare Materials, EarlyView.Schematic diagram depicting the fabrication and application of thymosin β4 (Tβ4)‐loaded microneedle patches for wound treatment. The Tβ4 was loaded into chitosan (CS) and sucrose MNs under mild conditions (4°C, 65% relative humidity). The Tβ4 MN patch specifically binds to the downregulated immune regulators Vsig4 and IL22rα2, thereby accelerating ...
Shilong He +4 more
wiley +1 more source
AlchemyThis study examines the extraction of keratin from chicken feather waste and its potential use as a coagulant in ochre dye solution treatment. The extraction procedure was investigated for the effect of some parameters, such as temperature (60 – 80 °C ...
Sri Wahyu Murni +3 more
doaj +1 more source
PLoS ONE, 2014 Epiplakin, a member of the plakin protein family, is exclusively expressed in epithelial tissues and was shown to bind to keratins. Epiplakin-deficient (EPPK-/-) mice showed no obvious spontaneous phenotype, however, EPPK-/- keratinocytes displayed ...
Karl L Wögenstein +8 more
doaj +1 more source
The Gain-of-Function Mutation p53R248W Suppresses Cell Proliferation and Invasion of Oral Squamous Cell Carcinoma through the Down-Regulation of Keratin 17 [PDF]
, 2020 Mayu Enaka +2 more
openalex +1 more source
Engineered Protein‐Based Ionic Conductors for Sustainable Energy Storage Applications
Advanced Materials, EarlyView.Rational incorporation of charged residues into an engineered, self‐assembling protein scaffold yields solid‐state protein films with outstanding ionic conductivity. Salt‐doping further enhances conductivity, an effect amplified in the engineered variants. These properties enable the material integration into an efficient supercapacitor.
Juan David Cortés‐Ossa +14 more
wiley +1 more source
Advanced Science, EarlyView.This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang +15 more
wiley +1 more source
Advanced Science, EarlyView.Inspired by epithelial tissue, epithelium‐like structure hydrogels are synthesized. The as‐prepared hydrogels exhibit ultrahigh toughness, ultralow hysteresis, and ultrahigh compressibility, which can be utilized as self‐powered and visual strain sensors.
Yutang Zhou +4 more
wiley +1 more source
PLoS ONE, 2013 Epithelial-to-mesenchymal transition (EMT), the phenotypical change of cells from an epithelial to a mesenchymal type, is thought to be a key event in invasion and metastasis of adenocarcinomas. These changes involve loss of keratin expression as well as
Katharina König +10 more
doaj +1 more source
Correlative Imaging Platform Linking Taste Cell Function to Molecular Identity
Advanced Science, EarlyView.A correlative imaging platform is developed to study how individual taste cells respond to different taste qualities. By linking cellular activity with molecular identity and environmental context, dual‐tuned taste cells capable of detecting both sweet and umami stimuli are identified.
Sungho Lee +6 more
wiley +1 more source
Fibril Structure of Desiccation‐Protective Tardigrade Protein CAHS‐8
Angewandte Chemie, EarlyView.We present the atomic structure of the fibril formed by an intrinsically disordered protein that has been shown to be responsible for remarkable environmental stress in tardigrades. X‐ray crystallography reveals a unique mechanism of fibril assembly whereby a single helix forms a stable, antiparallel coiled‐coil dimer, which then assembles into a ...
Anas Malki +6 more
wiley +2 more sources