Results 101 to 110 of about 57,590 (253)

DNA Nanotechnology Meets Peptide and Protein Self‐Assembly

Chemistry – A European Journal, EarlyView.
Combining DNA nanotechnology with peptide and protein assembly provides complementary platforms for the rational engineering of functional biomaterials. This Perspective discusses the emerging field of self‐assembling DNA‐peptide and DNA‐protein hybrid systems that combine the structural precision and programmability of DNA nanotechnology with the ...
Marcel Hanke, Nanjundan Raghul, Adrian Keller, Veikko Linko, Verónica I. Dodero   +4 more
wiley   +1 more source

Comparison Of Expression Levels Of Keratin 19 (Krt19) and Transmembrane Serine Protease 4 (Tmprss4) Genes in SU.86.86 and BxPC-3 Pancreatic Cancer Cell Lines

Genetics & Applications
In this study, the expression levels of Keratin 19 (KRT 19) and Transmembrane serine protease 4 (TMPRSS4) genes in metastatic pancreatic cancer cell line SU.86.86 and nonmetastatic pancreatic cancer cell line BxPC3 cells were been determined and the ...
Seda Yavuzarslan, Süreyya Bozkurt
doaj   +1 more source

Prediction of Acute Liver Injury Trajectory in Patients Following Acetaminophen Overdose: A Multibiomarker Machine Learning Proof‐of‐Concept Study

Clinical Pharmacology &Therapeutics, EarlyView.
Clinical translation of novel therapies can be hindered by heterogeneity‐driven sample size inflation in late‐stage trials. In acetaminophen‐induced liver injury (APAP DILI), many patients recover spontaneously, diluting investigational drug efficacy signals.
Chris Humphries, Alastair M. Kilpatrick, Kathleen M. Scullion, Rhona Aird, Lorraine Bruce, Maria Elena Candela, Tak Yung Man, Stuart J. Forbes, James W. Dear   +8 more
wiley   +1 more source

Carcinomas assemble a filamentous CXCL12-keratin-19 coating that suppresses T cell-mediated immune attack. [PDF]

Proc Natl Acad Sci U S A, 2022
Wang Z, Moresco P, Yan R, Li J, Gao Y, Biasci D, Yao M, Pearson J, Hechtman JF, Janowitz T, Zaidi RM, Weiss MJ, Fearon DT.   +12 more
europepmc   +1 more source

The Tissue-dependent Keratin 19 Gene Transcription Is Regulated by GKLF/KLF4 and Sp1

Journal of Biological Chemistry, 2000
Keratins play critical roles in cellular differentiation and cytoskeletal organization. Keratin 19 (K19) is unique because it has been implicated as a marker of stem cells in some tissues, such as the hair follicle in the skin. It is also associated with malignant transformation in esophageal and pancreatic cancers.
F H, Brembeck, A K, Rustgi
openaire   +2 more sources

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

Diagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source

Keratin 19 interacts with GSK3β to regulate its nuclear accumulation and degradation of cyclin D3. [PDF]

Mol Biol Cell, 2021
Sharma P, Tiufekchiev S, Lising V, Chung SW, Suk JS, Chung BM.   +5 more
europepmc   +1 more source

Microvascular Abnormalities in Adolescents With Anorexia Nervosa: Nailfold Video Capillaroscopic Evidence at Acute and Remission States

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Chronic malnutrition, hypothermia, and hormonal imbalance in anorexia nervosa (AN) may impair capillary structure and perfusion. This study aimed to describe the nailfold videocapillaroscopy (NVC) findings in adolescents with AN and atypical AN (AAN), to assess their association with Raynaud's phenomenon (RP), and evaluate ...
Muserref Kasap‐Cuceoglu, Melis Pehlivanturk‐Kizilkan, Erdal Sag, Seher Sener, Zeynep Balik, Sinem Akgul, Orhan Derman, Yelda Bilginer, Nuray Kanbur, Seza Özen   +9 more
wiley   +1 more source

The Clinicopathological Characteristics and Prognosis of Cholangiolocarcinoma: A Multicenter Study With a Central Pathology Review

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Cholangiolocarcinoma (CLC) is a rare liver cancer with ≥ 80% ductular configuration (DC). Given its rarity, its clinicopathological characteristics remain poorly understood, and its status as a distinct disease entity remains controversial.
Takamichi Ishii, Kenta Makino, Etsuro Hatano, Mina Komuta, Jun Akiba, Yoshihiro Sakamoto, Shun‐Ichi Ariizumi, Goro Honda, Toru Hisaka, Yutaka Takeda, Akira Shimizu, Kentaro Yasuchika, Takashi Mizuno, Daisuke Asano, Atsushi Fujio, Naoto Gotohda, Chie Kitami, Koji Amaya, Hiroshi Sadamori, Manabu Kawai, Akiyoshi Nakakura, Masafumi Nakamura, Itaru Endo   +22 more
wiley   +1 more source

Prognostic significance of inflammation-based prognostic scoring in patients with upper urinary tract urothelial carcinoma

International Brazilian Journal of Urology
Objectives: To investigate whether Glasgow Prognostic Score has prognostic significance in patients with upper urinary urothelial carcinoma. Patients and methods: We retrospectively reviewed the clinical records of 74 patients with upper urinary ...
Taisuke Suyama, Shigeki Kanbe, Masanobu Maegawa, Hirofumi Shimizu, Koichi Nakajima   +4 more
doaj   +1 more source