European Journal of Inorganic Chemistry, EarlyView.This work explores the influence of 6‐trifluoromethyluracil versus chloride counterions on the antibacterial and antitumoral activities of bis‐(1,10‐phenanthroline)chloridecopper(II) motif. The counterion modulates antibacterial potency and the identity of the dominant reactive species, while leaving DNA recognition by the shared cation essentially ...
Francisco Mastrobuono‐Cordeiro +14 more
wiley +1 more source
A bioinformatic single-cell and structure-informed framework identifies a baicalin-CA2-keratinocyte state axis in atopic dermatitis. [PDF]
PLoS OneYang B, Zhou G, Dai J.
europepmc +1 more source
Genetic variants of EcPV2 E6 and E7 in equine genital and oronasal squamous cell carcinoma
Equine Veterinary Journal, EarlyView.Abstract Background Since its discovery in 2008, equine papillomavirus type 2 (EcPV2) has been detected in up to 100% of equine genital and up to 40% of equine oronasal squamous cell carcinomas (SCCs). Preliminary sequence data point to the existence of EcPV2 E6 and E7 oncogene variants compared to the British reference sequence from 2008.
Maya Jenner, Sabine Brandt
wiley +1 more source
AI-Assisted Quantitative Reflectance Confocal Microscopy Reveals Modulation of Senescence-Associated Epidermal Morphometric Features by a Topical TGF-β Mimetic, XEP™-716 Miniprotein™. [PDF]
Dermatol Ther (Heidelb)Chajra H +6 more
europepmc +1 more source
Untethered Electrical Stimulation Using Optoelectricity and Piezoelectricity for Tissue Regeneration
FlexTech, EarlyView.Untethered electrical stimulation from optoelectronic and piezoelectric materials can aid regeneration of damaged tissue. ABSTRACT Electrical signals are increasingly recognized as important regulators of tissue development and regeneration, with outcomes linked to behaviors including proliferation, differentiation, cell migration, and more.
Ryan Yao, Baochun Xu, Cunjiang Yu
wiley +1 more source
Epigenomic Characterization of Fibroblasts in Darier Disease Identifies Cross-cell-type Regulatory Gene Signatures. [PDF]
Acta Derm VenereolWang N +4 more
europepmc +1 more source
Hydrogel‐Based Bioelectronics: From Therapy and Sensing to Neuromorphic Computation
FlexTech, EarlyView.This review establishes a material–conduction–property–application framework connecting hydrogel chemistry and charge transport with therapy, sensing, closed‐loop feedback, and neuromorphic computation. ABSTRACT Bioelectronics establish bidirectional communication between living systems and electronic devices, providing an enabling platform for ...
Jianlong Hong +7 more
wiley +1 more source
Giant Keratinocyte Carcinomas: Clinical, Histopathological, Molecular and Health-System Factors with Therapeutic Implications-A Structured Narrative Review. [PDF]
Cancers (Basel)Ciborek A +3 more
europepmc +1 more source
FlexMat, EarlyView.In this work, we first examine the limitations of surgical repair and stenting, including migration, granulation, mucus plugging, and infection. We then translate these failures into engineering constraints involving geometry, mechanics, fixation, degradation, junctional stress, and remodeling.
Yiwei Xu +6 more
wiley +1 more source