Balancing the skin: antagonistic ubiquitin-like signaling pathways govern epidermal homeostasis. [PDF]
Rietscher K, Klein B.
europepmc +1 more source
ABSTRACT Background Robust outcome data for anterior skull base cutaneous squamous cell carcinoma (cSCC) are limited, particularly as emerging therapies reshape management. We evaluated survival and prognostic factors following craniofacial resection. Methods Retrospective multi‐institutional case‐series (1995–2015) of patients who underwent skull base
Michael J. C. Schachtel +52 more
wiley +1 more source
Machine learning-derived R-loop-related diagnostic signature for psoriasis: a multi-cohort and single-cell validation study. [PDF]
Feng Y +5 more
europepmc +1 more source
Viability of Tumor Cells in Bone Dust: Implications for Oncologic Skull Base Surgery
ABSTRACT Background Head and neck tumors with skull base involvement may require drilling of tumor infiltrated bone. We hypothesize that bone dust generated during this process contains viable tumor cells that may seed the surgical field. Methods Tumors with gross bone invasion were drilled, and dust was collected for H&E, cell viability analysis, and ...
Kelly Bridgham +14 more
wiley +1 more source
Inhibition of 3-Phosphoinositide-Dependent Kinase 1 Improves Age-Associated Epidermal Dysfunction. [PDF]
Cho SY +9 more
europepmc +1 more source
ABSTRACT Background To characterize the clinicoepidemiologic profile of HIV‐associated oral Kaposi sarcoma (OKS) and quantitatively synthesize its frequency, anatomical distribution, and temporal patterns across antiretroviral therapy (ART) eras. Methods Six databases and gray literature were searched.
Ericles Otávio +10 more
wiley +1 more source
Objectively Measured Photoaging and Skin Cancer in Organ Transplant Recipients. [PDF]
Wiegell SR +5 more
europepmc +1 more source
ABSTRACT Background Immunotherapy is increasingly used for head and neck cutaneous squamous cell carcinoma (cSCC) with perineural spread (PNS), though outcomes remain poorly defined. Methods A systematic review was conducted according to PRISMA and MOOSE guidelines.
Jai Paris +4 more
wiley +1 more source
TRIM28 Promotes Keratinocyte Proliferation and Invasion by Activating NLRP3/SGT1 Axis-Mediated Macrophage Pro-Inflammatory Polarization in an In Vitro Macrophage-Keratinocyte Co-Culture Model. [PDF]
Gao Z, Zhang X, Wang J, Yang N.
europepmc +1 more source
Combining advanced 3D spheroid-based skin models with deep-learning-based image analysis enables in-depth investigation of keratinocyte differentiation and barrier function. [PDF]
Cesetti T +10 more
europepmc +1 more source

