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Non-Surgical Treatments for Keratinocyte Carcinomas

Advances in Therapy, 2021
Skin cancer is the most common malignancy worldwide, comprising approximately 30% of all human tumors. In recent decades, the incidence of keratinocyte carcinomas, which include basal cell carcinoma and cutaneous squamous cell carcinoma, has been steadily increasing globally (Rogers et al. in JAMA Dermatol 151(10):1081-1086.
Kylee J B, Kus, Emily S, Ruiz
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Review of Perineural Invasion in Keratinocyte Carcinomas

American Journal of Clinical Dermatology, 2021
Perineural invasion is an infiltrative process of peripheral nerves by the primary neoplasm within the immediate vicinity. Aggressive forms of keratinocyte carcinomas, such as basal cell and squamous cell carcinomas, may feature perineural invasion, which is often associated with tumor recurrence and poorer prognosis. Diagnosis requires a high clinical
Albert E. Zhou   +2 more
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Chemoprevention of Keratinocyte Carcinomas

2021
This chapter focuses on the use of retinoids in the chemoprevention of keratinocyte carcinomas (KC) and will aim to demystify their use in the clinical arena by offering a practical approach to optimize clinical benefits and minimize adverse effects. The last decade has ushered in a handful of agents with demonstrated efficacy in the prevention of KC ...
Olivia M. Lucero   +2 more
openaire   +1 more source

Hypofractionated Radiation Therapy in Keratinocyte Carcinoma

Clinical Oncology, 2022
Hypofractionated radiation therapy regimens are well suited to the management of keratinocyte carcinomas. Most lesions are small, superficial and not close to critical organs at risk. Fewer visits to the cancer centre are advantageous for the frail and elderly patient population.
M.N. Tsao   +3 more
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Update on Keratinocyte Carcinomas

New England Journal of Medicine, 2018
Keratinocyte Carcinomas Squamous-cell and basal-cell carcinomas of the skin are increasing in frequency.
Kishwer S, Nehal   +1 more
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Reliability of the histopathologic diagnosis of keratinocyte carcinomas

Journal of the American Academy of Dermatology, 2007
We sought to determine the interobserver reliability of the histopathologic diagnosis of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) (keratinocyte carcinomas) in the setting of a Department of Veteran Affairs multicenter chemoprevention study.Interobserver concordance was assessed by blinded review of histopathologic slides by study ...
Jared, Jagdeo   +3 more
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Chemoprevention of Keratinocyte Carcinomas: An Updated Review

American Journal of Clinical Dermatology, 2016
A well-established link between ultraviolet exposure and the carcinogenesis of keratinocyte carcinomas exists. Despite increased sun protection efforts, skin cancer remains the most common cancer in the USA. Numerous studies on the topic of chemoprevention investigate alternative topical, oral, and injectable agents to reduce skin cancer incidence in ...
Jessica, Mounessa   +3 more
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Medications Associated with Increased Risk of Keratinocyte Carcinoma

Dermatologic Clinics, 2019
A number of medications for short-term and long-term use have been linked to an increased risk for keratinocyte carcinoma (KC). Immunosuppressive medications are associated with an increased risk for KC and melanoma due to reduction of antitumor immune surveillance, and some immunosuppressive agents directly impact DNA replication and repair.
Sarah T Arron, Lauren D Crow
exaly   +3 more sources

Interventions for preventing keratinocytic cancer in patients with a history of a previous keratinocytic carcinoma: A systematic review

International Journal of Dermatology, 2022
AbstractKeratinocyte cancer (KC) is the most common cancer worldwide. It is important to analyze the actual interventions that are available for the prevention of patients with a previous history of a KC. We aim to review the existent literature to assess the efficacy and safety of interventions to prevent KC in patients with a history of previous KC ...
María José García‐Alonso   +3 more
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Keratinocyte Carcinoma

JAMA
Importance Keratinocyte carcinomas are skin cancers that arise from keratinocytes and are composed of basal cell carcinomas (BCCs) and cutaneous squamous cell carcinomas (cSCCs). Keratinocyte carcinomas are common in North America, Australia, New Zealand, and Europe.
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