Results 191 to 200 of about 1,560,167 (291)

A pilot study using immunohistochemical staining to characterize dihydropyrimidine dehydrogenase expression in keratinocyte neoplasms

JAAD International, 2023
Ogechi Ikediobi, MD, PhD, Jennifer Y. Sui, BA, Caitlyn Kellogg, MD, Andrea Roso Mares, MD, Shota Takashima, MD, PhD, Julia D. Bertini, Brianne Daniels, DO, Brian Hinds, MD, Bryan K. Sun, MD, PhD   +8 more
doaj   +1 more source

A joint learning approach for automated diagnosis of keratinocyte carcinoma using optical attenuation coefficients. [PDF]

NPJ Digit Med
Zhang L, Li X, Chen W, Gu Y, Wu H, Lu Z, Dong B.   +6 more
europepmc   +1 more source

Genetic evolution of keratinocytes to cutaneous squamous cell carcinoma

AbstractWe performed multi-omic profiling of epidermal keratinocytes, precancerous actinic keratoses, and squamous cell carcinomas to understand the molecular transitions during skin carcinogenesis. Single-cell mutational analyses of normal skin cells showed that most keratinocytes have remarkably low mutation burdens, despite decades of sun exposure ...
Bishal Tandukar, Delahny Deivendran, Limin Chen, Noel Cruz-Pacheco, Harsh Sharma, Albert Xu, Aravind K. Bandari, Daniel B. Chen, Christopher George, Annika Marty, Raymond J. Cho, Jeffrey Cheng, Drew Saylor, Pedram Gerami, Sarah T. Arron, Boris C. Bastian, A. Hunter Shain   +16 more
openaire   +2 more sources

Alleviation of photoaging‐associated MMP upregulation, prostanoid biosynthesis, and cell cycle arrest with titanium dioxide, zinc oxide, and inorganic‐only (ZnO + TiO2) sunscreens

Photochemistry and Photobiology, EarlyView.
Inorganic sunscreens containing the UV filters titanium dioxide (TiO2) and/or zinc oxide (ZnO) alleviated various biomarkers of photoaging in human dermal fibroblasts, at a gene and protein level. The study provides novel insights that observe the impact of inorganic photoprotection through the molecular biology of skin.
Neil Dominic T. Pangilinan, Mohammad Shalbaf, Aline Souza, Bhaven Chavan, Mark A. Birch‐Machin   +4 more
wiley   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma. [PDF]

Mol Oncol
Ramchatesingh B, Martinez Villarreal A, Lefrançois P, Gantchev J, Sivachandran S, Abou Setah S, Litvinov IV.   +6 more
europepmc   +1 more source

Developing a risk prediction model for keratinocyte carcinoma in patients with actinic keratosis. [PDF]

Br J Dermatol, 2020
Kim Y, Jorgenson E, Asgari MM.
europepmc   +1 more source

Transcriptional benchmark dose modeling of ultraviolet radiation‐induced genomic activation in mouse skin

Photochemistry and Photobiology, EarlyView.
Exposure to ultraviolet radiation (UV‐R) from tanning equipment increases skin cancer risk through molecular changes, but genomic thresholds remain unclear. Using mice, we examined dose‐ and time‐dependent gene expression after erythemally‐weighted UV‐R doses (0–40 mJ/cm2).
Sami S. Qutob, Samantha P. M. Roesch, Sandy Smiley, Pascale V. Bellier, Andrew Williams, Kate B. Cook, Matthew J. Meier, Andrea Rowan‐Carroll, Carole L. Yauk, James P. McNamee, Vinita Chauhan   +10 more
wiley   +1 more source

Dermatological Adverse Events Associated With Lapatinib Treatment in Dogs With Urothelial Carcinoma: A Retrospective Study

Veterinary Dermatology, EarlyView.
Lapatinib is widely used in human oncology; however, dermatological adverse events (DAEs) are common and have been correlated with treatment efficacy. In veterinary medicine, lapatinib use in combination with piroxicam has been shown to be effective in treating canine urothelial carcinoma (UC); however, the incidence and prognostic significance of DAEs
Kosuke Horita, Tomohiro Yonezawa, Yasuyuki Momoi, Shingo Maeda   +3 more
wiley   +1 more source

Cutaneotropic polyomavirus abundance in the nonlesional skin of keratinocyte carcinoma patients: A cross-sectional study. [PDF]

J Am Acad Dermatol
Zhou EY, Xia Y, Oka T, Higuchi H, Hasegawa T, Park JH, Marchese E, Oliver-García VS, Azin M, Conrad DN, Smith SS, Neel VA, Demehri S.   +12 more
europepmc   +1 more source

Skin cancer burden in lung transplant recipients:we need to do better! [PDF]

, 2020
Harwood, C. A., Proby, C. M.
core   +2 more sources