Results 171 to 180 of about 639,835 (244)

Dermatologic Toxicities Associated With Novel Pan‐RAS/RAF Inhibitors

Journal of Cutaneous Pathology, Volume 53, Issue 11, Page 1042-1050, November 2026.
ABSTRACT Background The mitogen‐activated protein kinase (MAPK) pathway plays a key role in cell‐cycle regulation and tumor progression in cancer. Dermatologic toxicities (DTs) to newer pan‐RAS (RMC‐6236) and pan‐RAF (LXH254/naporafenib) inhibitors are emerging.
Lin J. He, Shaymaa Hegazy, Phyu P. Aung, Priyadharsini Nagarajan, Fiorinda Muhaj, Adrienne N. Choksi, Ana M. Ciurea, Kelly C. Nelson, Doina Ivan, Carlos A. Torres‐ Cabala, Victor G. Prieto, Jonathan L. Curry   +11 more
wiley   +1 more source

Counting keratinocyte carcinomas as a step to preventing them [PDF]

Journal of the American Academy of Dermatology, 2019
Meghan, Beatson, Angelica, Misitzis, Martin A, Weinstock   +2 more
openaire   +2 more sources

A pilot study using immunohistochemical staining to characterize dihydropyrimidine dehydrogenase expression in keratinocyte neoplasms

JAAD International, 2023
Ogechi Ikediobi, MD, PhD, Jennifer Y. Sui, BA, Caitlyn Kellogg, MD, Andrea Roso Mares, MD, Shota Takashima, MD, PhD, Julia D. Bertini, Brianne Daniels, DO, Brian Hinds, MD, Bryan K. Sun, MD, PhD   +8 more
doaj   +1 more source

A joint learning approach for automated diagnosis of keratinocyte carcinoma using optical attenuation coefficients. [PDF]

NPJ Digit Med
Zhang L, Li X, Chen W, Gu Y, Wu H, Lu Z, Dong B.   +6 more
europepmc   +1 more source

Design Considerations for Polymer–Deep Eutectic Solvent Hybrid Systems for Transdermal Drug Delivery

Journal of Applied Polymer Science, Volume 143, Issue 40, October 20, 2026.
Deep eutectic solvents (DESs) act as tunable, green excipients that modulate polymer structure–property relationships to enhance drug solubility, skin permeation, stability, and controlled release. Through hydrogen‐bond interactions, DES–polymer hybrid systems enable improved transdermal performance, offering a rational, design‐driven platform for ...
Madhavi Kailas Kapale, Madhur Kulkarni, Pranav J. Shah, Furqan A. Maulvi   +3 more
wiley   +1 more source

Analysis of race in time to keratinocyte carcinoma in solid organ transplant recipients: Results of a single-institution study. [PDF]

J Am Acad Dermatol
Silva I, Kazmi A, Hren MG, Ji AL.
europepmc   +1 more source

Bioactive peptides in cancer and inflammation: Mechanisms, model systems and clinical translation

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Bioactive peptides (BAPs) derived from host, marine, insect, plant and synthetic sources share cationic, amphipathic structures adopting α‐helical, β‐sheet or cyclic conformations. These features underlie anti‐cancer effects, including membrane disruption, apoptosis and cell‐cycle arrest, anti‐metastatic activity, reduced invasion and migration, and ...
Najwa Doha, Richa Gill, Sergio Crovella, Haissam Abou‐Saleh, Sahar Isa Da'as   +4 more
wiley   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma. [PDF]

Mol Oncol
Ramchatesingh B, Martinez Villarreal A, Lefrançois P, Gantchev J, Sivachandran S, Abou Setah S, Litvinov IV.   +6 more
europepmc   +1 more source

Developing a risk prediction model for keratinocyte carcinoma in patients with actinic keratosis. [PDF]

Br J Dermatol, 2020
Kim Y, Jorgenson E, Asgari MM.
europepmc   +1 more source

Cathepsin L in cancer: Context‐dependent functions, microenvironmental regulation and translational opportunities

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Cathepsin L (CTSL) acts as a context‐dependent facilitator of tumour progression rather than a universal oncogenic driver. CTSL's pro‐tumorigenic functions are critically evaluated alongside its inherent biochemical constraints and family‐wide redundancy. CTSL‐related biology may provide translational opportunities in selected contexts.
Yujun Wu, Qin Huang, Zixuan Ding, Lin Fu, Mu Yang, Bi Peng, Pengbo Hu, Yuanhui Liu   +7 more
wiley   +1 more source