Results 31 to 40 of about 74,447 (392)
EBioMedicine, 2016 A validated animal model would assist with research on the immunological consequences of the chronic expression of stress keratins KRT6, KRT16, and KRT17, as observed in human pre-malignant hyperproliferative epithelium.
Samal Zhussupbekova +5 more
doaj +1 more source
European Journal of Histochemistry, 2021 This pilot study was aimed at comparing TLR7/TLR9 expression, cytoskeletal arrangement, and cell proliferation by indirect immunofluorescence in parallel lesional and non lesional skin samples of guttate psoriasis (PG) and psoriasis vulgaris (PV) in five
Francesca Prignano +5 more
doaj +1 more source
Tissue-Specific Transcriptomes Reveal Gene Expression Trajectories in Two Maturing Skin Epithelial Layers in Zebrafish Embryos. [PDF]
, 2019 Epithelial cells are the building blocks of many organs, including skin. The vertebrate skin initially consists of two epithelial layers, the outer periderm and inner basal cell layers, which have distinct properties, functions, and fates.
Cokus, Shawn J +6 more
core +2 more sources
Human Genomics, 2018 Background Mutations in keratin proteins have been vastly associated with a wide array of genodermatoses; however, mutations of keratins in psoriasis have not been fully investigated.
Tamilselvi Elango +7 more
doaj +1 more source
Keratins in Skin Epidermal Development and Diseases
Keratin, 2018 Epidermal keratinocyte (KC), the major cell type in the skin epidermis, plays critical roles in forming a permeability barrier to separate internal organs from external stimuli.
Ling-juan Zhang
semanticscholar +1 more source
Sedimentation Studies of Epidermal Keratins. Keratin A and Keratin B [PDF]
The Journal of Cell Biology, 1956 Electrophoretically homogeneous keratin A and keratin B were studied in the ultracentrifuge. Both preparations revealed two fractions: one which sedimented rapidly and another which sedimented slowly. This indicated that both preparations are heterogeneous with respect to particle size.
openaire +3 more sources
Keratin 17 Suppresses Cell Proliferation and Epithelial-Mesenchymal Transition in Pancreatic Cancer
Frontiers in Medicine, 2020 Keratin 17 (K17), a member of type I acidic epithelial keratin family, has been reported to be upregulated in many malignant tumors and to be involved in promoting the development of tumors.
Yong Zeng +7 more
doaj +1 more source
Soft epidermis of a scaleless snake lacks beta-keratin
European Journal of Histochemistry, 2009 Beta-keratins are responsible for the mechanical resistance of scales in reptiles. In a scaleless crotalus snake (Crotalus atrox), large areas of the skin are completely devoid of scales, and the skin appears delicate and wrinkled.
M Toni, L Alibardi
doaj +1 more source
Cancer Medicine, 2020 Aims The dynamics and topographical distribution of SOX17 and SOX2 expression was studied in the transformation zone (TZ) of the uterine cervix. This TZ is a dynamic area where switches from glandular into squamous epithelium can be recognized, new ...
Jobran M. Moshi +10 more
doaj +1 more source
The molecular genetic analysis of the expanding pachyonychia congenita case collection [PDF]
, 2014 BACKGROUND: Pachyonychia congenita (PC) is a rare autosomal dominant keratinizing disorder characterized by severe, painful, palmoplantar keratoderma and nail dystrophy, often accompanied by oral leucokeratosis, cysts and follicular keratosis.
Al-Asadi, E. +9 more
core +2 more sources