Results 41 to 50 of about 74,447 (392)
Molecular Therapy: Methods & Clinical Development, 2017 Epidermolysis bullosa simplex (EBS) is a blistering skin disease caused by dominant-negative mutations in either KRT5 or KRT14, resulting in impairment of keratin filament structure and epidermal fragility.
Magomet Aushev +4 more
doaj +1 more source
Molecular manipulation of keratin 8/18 intermediate filaments: modulators of FAS-mediated death signaling in human ovarian granulosa tumor cells [PDF]
, 2016 Background: Granulosa cell tumors (GCT) are a rare ovarian neoplasm but prognosis is poor following recurrence. Keratin intermediate filaments expressed in these tumors are a diagnostic marker, yet paradoxically, may also constitute a target for ...
Davis, John S. +4 more
core +3 more sources
Frontiers in Immunology, 2018 Thymic epithelial cells are one of the main components of the thymic microenvironment required for T-cell development. In this work, we describe an efficient method free of enzymatic and Facs-sorted methods to culture human medullary thymic epithelial ...
José A. Villegas +7 more
doaj +1 more source
Pathophysiology of keratinization
Journal of Oral and Maxillofacial Pathology, 2018 Cytoskeleton of a cell is made up of microfilaments, microtubules and intermediate filaments. Keratins are diverse proteins. These intermediate filaments maintain the structural integrity of the keratinocytes. The word keratin covers these intermediate filament-forming proteins within the keratinocytes.
Revati Deshmukh, Priya Nimish Deo
openaire +3 more sources
Molecules, 2018 Antimicrobial photodynamic therapy (aPDT) has been proposed as an alternative method for oral candidiasis (OC), while nanocarriers have been used to improve the water solubility of curcumin (CUR).
Vinicius Tatsuyuji Sakima +6 more
doaj +1 more source
THE SPECIFICITY OF KERATINS [PDF]
Journal of Experimental Medicine, 1939 Kerateine and metakeratin were prepared from wool, chicken feathers and human hair. Chemical analyses revealed that the compounds are closely related. The results of serological studies disclose that species specificity is an individual characteristic of the keratins employed and that the specificity observed is dependent on the redox ...
E. E. Ecker, J. R. Wells, Louis Pillemer
openaire +3 more sources
Animal Research and One Health, EarlyView., 2023 In our study, we conducted circRNA expression profiling of Zhongwei goat skin exhibiting divergent curvature wool phenotypes at two developmental stages using the RNA‐seq. Functional verification assay demonstrated that circRNA8782 regulated fibroblast proliferation.
Yingxiao Su +9 more
wiley +1 more source
The Amount of Keratins Matters for Stress Protection of the Colonic Epithelium
PLoS ONE, 2015 Keratins (K) are important for epithelial stress protection as evidenced by keratin mutations predisposing to human liver diseases and possibly inflammatory bowel diseases.
M. Nadeem Asghar +7 more
semanticscholar +1 more source
Response of xenografts of developing human female reproductive tracts to the synthetic estrogen, diethylstilbestrol. [PDF]
, 2017 Human female fetal reproductive tracts 9.5-22 weeks of gestation were grown for 1 month in ovariectomized athymic adult female mouse hosts that were either untreated or treated continuously with diethylstilbestrol (DES) via subcutaneous pellet.
Baskin, Laurence +5 more
core +2 more sources
Expression of keratins, epidermal proteins and inflammatory cells in superficial pemphigus dogs [PDF]
Bulgarian Journal of Veterinary Medicine, 2018 Superficial pemphigus in dogs is an autoimmune skin disorder. The disease is characterised by the binding of auto-antibodies to desmosomal molecules including desmocollin-1, a major auto-antigen in dogs.
S. Theerawatanasirikul +3 more
doaj +1 more source