Results 81 to 90 of about 25,346 (314)

Significance of stress keratin expression in normal and diseased epithelia

iScience
Summary: A group of keratin intermediate filament genes, the type II KRT6A-C and type I KRT16 and KRT17, are deemed stress responsive as they are induced in keratinocytes of surface epithelia in response to environmental stressors, in skin disorders (e.g.
Erez Cohen, Craig N. Johnson, Rachael Wasikowski, Allison C. Billi, Lam C. Tsoi, J. Michelle Kahlenberg, Johann E. Gudjonsson, Pierre A. Coulombe   +7 more
doaj  

Mass spectrometry data from proteomic analysis of human skin keratins after exposure to UV radiation

Data in Brief, 2016
A mass spectrometry (MS)-based proteomic methodology was employed to monitor oxidative modifications in keratins, the main constituents of human skin (“Non-invasive proteomic analysis of human skin keratins: screening of methionine oxidation in keratins ...
Seon Hwa Lee, Keita Matsushima, Kohei Miyamoto, Tomoyuki Oe   +3 more
doaj  

Engineered Tissue Models to Decode Host–Microbiota Interactions

Advanced Science, EarlyView.
Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio, Grace E. Callen, Xuesong He, Bruce J. Paster, Hatice Hasturk, Chiara E. Ghezzi   +5 more
wiley   +1 more source

Keratin

In the ever-evolving landscape of materials science, the pursuit of sustainable and high-performance materials has led to a renewed interest in biopolymer composites. These materials, which blend the natural advantages of biopolymers with the enhanced properties of composite structures, present a promising frontier for innovation across various ...
Mishra, Dinesh Kumar, Khare, Sundaram
openaire   +1 more source

The New Keratin Nomenclature [PDF]

Journal of Investigative Dermatology, 2006
When the first nomenclature of the keratin protein family was published over 20 years ago, only 19 keratins were thought to exist. Sequencing of the human genome has now revealed that there are 54 keratin genes. As a consequence, the nomenclature needed revision to apply a logical numbering system that includes the more recently identified keratins of ...
openaire   +3 more sources

Keratin-based Nanofibres [PDF]

, 2010
There's Plenty of Room at the Bottom" ? this was the title of the lecture Prof. Richard Feynman delivered at California Institute of Technology on December 29, 1959 at the American Physical Society meeting. He considered the possibility to manipulate matter on an atomic scale.
Tonin C, Aluigi A, Varesano A, Vineis C
openaire   +3 more sources

Keratins Are Altered in Intestinal Disease-Related Stress Responses

Cells, 2016
Keratin (K) intermediate filaments can be divided into type I/type II proteins, which form obligate heteropolymers. Epithelial cells express type I-type II keratin pairs, and K7, K8 (type II) and K18, K19 and K20 (type I) are the primary keratins found ...
Terhi O. Helenius, Cecilia A. Antman, Muhammad Nadeem Asghar, Joel H. Nyström, Diana M. Toivola   +4 more
doaj   +1 more source

Distinct CTC Specific RNA Profile Enables NSCLC Early Detection and Dynamic Monitoring of Advanced NSCLC

Advanced Science, EarlyView.
A quantitative CTC RNA assay is developed by incorporating multi‐antibody‐based CTC isolation and specific mRNA quantification using RT‐ddPCR. The NSCLC CTC ScoreD demonstrates high accuracy for early‐stage NSCLC detection, significantly outperforming serum CEA. NSCLC CTC ScoreM exhibits a more accurate early‐warning of responses to different therapies
Xiaoyu Wang, Pi Ding, Wenjuan Xu, Lei Qiu, Jing Ren, Yucheng Fei, Zhili Wang, Cheng Li, Yufei Xing, Mingjing Shen, Yawen Zhu, Yun Guo, Na Sun, Renjun Pei, Minhua Shi   +14 more
wiley   +1 more source

CD103+ T Cells Eliminate Damaged Alveolar Epithelial Type II Cells Under Oxidative Stress to Prevent Lung Tumorigenesis

Advanced Science, EarlyView.
This work unravels a novel function of CD103+ T cells in eradicating oxidative‐stressed somatic cells to prevent lung tumorigenesis and identifies specific CD103+ T cell‐decline as a key feature in the aged lung. This comprehensive study highlights the contribution of immuno‐dysregulation to the high incidence of aging‐associated lung cancers ...
Yu Xu, Haorui Luo, Jiahao Wang, Haifeng Liu, Luonan Chen, Hongbin Ji, Zimu Deng, Xiaolong Liu   +7 more
wiley   +1 more source

Human hair keratins

Journal of Investigative Dermatology, 1993
Human hair keratins were among the first to be studied but it is only recently that sufficient information has been obtained to gain a basic biologic perspective of these proteins. Hair keratins are members of the intermediate filament family of proteins, yet are sufficiently divergent from epidermal keratins to warrant separate classification: type Ia
Da-wen Yu, Arthur P. Bertolino, Daniel M. Checkla, Irwin M. Freedberg, Jialin Yu   +4 more
openaire   +3 more sources