Results 1 to 10 of about 3,198 (129)
Effects of Repetitive Transcranial Magnetic Stimulation on Pallidum GABAergic Neurons and Motor Function in Rat Models of Kernicterus [PDF]
Brain Sciences, 2023 Kernicterus is a serious complication of hyperbilirubinemia, caused by neuronal injury due to excessive unconjugated bilirubin (UCB) in specific brain areas.
Nanqin Wang +5 more
doaj +2 more sources
The Importance of Neuroimaging Follow-Up in Bilirubin-Induced Encephalopathy: A Clinical Case Review [PDF]
Brain SciencesIntroduction: Hyperbilirubinemia in newborns can lead to kernicterus, a severe form of neonatal encephalopathy caused by bilirubin toxicity. Despite timely interventions such as exchange transfusion, kernicterus can still develop, especially in high-risk
Martina Resaz +5 more
doaj +2 more sources
Developmental outcome of severe neonatal indirect hyperbilirubinemia [PDF]
Journal of Research in Clinical Medicine, 2021 Background: Indirect hyperbilirubinemia is one of the most common causes of hospitalization in the neonatal period and its potential association with brain damage is well established.
Manizheh Mostafa Gharehbaghi +3 more
doaj +1 more source
Cells, 2023 Bilirubin-induced neurological damage (BIND), which might progress to kernicterus, occurs as a consequence of defects in the bilirubin conjugation machinery, thus enabling albumin-unbound free bilirubin (BF) to cross the blood–brain barrier and ...
Abida Islam Pranty +2 more
doaj +1 more source
Radiology Case Reports, 2018 Characteristic magnetic resonance imaging (MRI) findings in patients with chronic kernicterus are bilateral and symmetric T2-weighted hyperintensities in the globus pallidus.
Getachew Assefa Neknek, MD +3 more
doaj +1 more source
Clinicopathological Spectrum of Bilirubin Encephalopathy/Kernicterus
Diagnostics, 2019 Bilirubin encephalopathy/kernicterus is relatively rare, but continues to occur despite universal newborn screening. What is more interesting is the spectrum of clinical and even neuropathological findings that have been reported in the literature to be ...
Sumit Das, Frank K.H. van Landeghem
doaj +1 more source
Bilirubin-Induced Transcriptomic Imprinting in Neonatal Hyperbilirubinemia
Biology, 2023 Recent findings indicated aberrant epigenetic control of the central nervous system (CNS) development in hyperbilirubinemic Gunn rats as an additional cause of cerebellar hypoplasia, the landmark of bilirubin neurotoxicity in rodents.
John Paul Llido +7 more
doaj +1 more source
Genetic Association of UGT1A1 Promoter Variants (c.-3279T>G and c.-3156G>A) with Neonatal Hyperbili-rubinemia in an Iranian Population [PDF]
Iranian Journal of Neonatology, 2021 Background: Several studies have reported that two promoter variants (c.-3279T>G and c.-3156G>A) in UDP-glucuronosyltransferase (UGT1A1) gene may contribute to neonatal hyperbilirubinemia.
Nasim Pouralizadeh +6 more
doaj +1 more source
Cell Transplantation, 2022 Kernicterus is a permanent condition caused by brain damage from bilirubin toxicity. Dystonia is one of the most debilitating symptoms of kernicterus and results from damage to the globus pallidus (GP).
Fu-Chen Yang +4 more
doaj +1 more source