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A review of antibiotic safety in pregnancy—2025 update [PDF]

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 4, Page 227-237, April 2025.
Abstract Antibiotics constitute the majority of prescriptions for women during pregnancy. Common bacterial infections, including urinary tract infections, skin and soft tissue infections, and upper and lower respiratory tract infections, are expected in pregnancy, similar to the general public.
Johny Nguyen   +8 more
wiley   +2 more sources

Status Dystonicus in Children: Is it more Common than we Realize?

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Status dystonicus (SD) is the most severe form of dystonia, affecting predominantly children. SD is thought to be rare, but the incidence is unknown. Objective We aimed to: (1) assess the number of admissions involving SD (2) describe complications/intensive care unit (ICU) transfers, and (3) evaluate whether these changed with ...
Nadia Al Azri   +6 more
wiley   +1 more source

Chinese Clinical Practice Guidelines for Auditory Neuropathy (gCAN)

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Auditory neuropathy (AN) is an auditory disorder that affects the function of the auditory pathway. An increasing number of AN cases have been identified with the revelation of the underlying mechanisms, the advancements of diagnostic and detecting techniques.
Chinese Multi‐Center Research Collaborative Group on Clinical Diagnosis and Intervention of Auditory Neuropathy; Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery; Society of Otorhinolaryngology Head and Neck Surgery   +43 more
wiley   +1 more source

Tri‐M2MT: Multi‐modalities based effective acute bilirubin encephalopathy diagnosis through multi‐transformer using neonatal Magnetic Resonance Imaging

open access: yesCAAI Transactions on Intelligence Technology, Volume 10, Issue 2, Page 434-449, April 2025.
Abstract Acute Bilirubin Encephalopathy (ABE) is a significant threat to neonates and it leads to disability and high mortality rates. Detecting and treating ABE promptly is important to prevent further complications and long‐term issues. Recent studies have explored ABE diagnosis.
Kumar Perumal   +3 more
wiley   +1 more source

Factors Affecting the Relationship Between Total and Unbound Bilirubin in Preterm and Term Infants

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim Newborn infants universally experience jaundice, most of which is physiologic, but in some high‐risk situations, it may lead to neurological dysfunction or death. Unbound bilirubin (Bf) may be the best predictor of bilirubin toxicity in this population. The goal of the study is to examine the relationship between total serum bilirubin (TSB)
Thomas Hegyi   +6 more
wiley   +1 more source

The risk of epilepsy after neonatal seizures

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16288 Abstract Aim To estimate the cumulative risk of epilepsy after neonatal seizures and identify subpopulations at increased risk. Method This was a nationwide register‐based cohort study including all children born in Denmark between 1997 and 2018.
Jeanette Tinggaard   +6 more
wiley   +1 more source

Anti‐Ce in haemolytic disease of the foetus and newborn

open access: yesTransfusion Medicine, EarlyView.
Abstract Objectives To report a delayed case of severe haemolytic disease of the foetus and newborn (HDFN) due to Anti‐Ce. Background HDFN due to maternal antibodies is potentially fatal. As a result, antibody levels and foetal anaemia are periodically monitored and risk assessed throughout pregnancy. HDFN due to Anti‐Ce is rare.
Rebecca O'Grady   +6 more
wiley   +1 more source

Improved genetic screening with zygosity detection through multiplex high‐resolution melting curve analysis and biochemical characterisation for G6PD deficiency

open access: yesTropical Medicine &International Health, Volume 30, Issue 5, Page 437-457, May 2025.
Abstract Accurate diagnosis of glucose‐6‐phosphate dehydrogenase (G6PD) deficiency is crucial for relapse malaria treatment using 8‐aminoquinolines (primaquine and tafenoquine), which can trigger haemolytic anaemia in G6PD‐deficient individuals. This is particularly important in regions where the prevalence of G6PD deficiency exceeds 3%–5%, including ...
Usa Boonyuen   +11 more
wiley   +1 more source

The Role of Proton Magnetic Resonance Spectroscopy in Neonatal and Fetal Brain Research

open access: yesJournal of Magnetic Resonance Imaging, Volume 61, Issue 6, Page 2404-2424, June 2025.
The biochemical composition and structure of the brain are in a rapid change during the exuberant stage of fetal and neonatal development. 1H‐MRS is a noninvasive tool that can evaluate brain metabolites in healthy fetuses and infants as well as those with neurological diseases.
Steve C.N. Hui   +2 more
wiley   +1 more source

Integrated Phenotypic and Genotypic Approaches for Accurate Diagnosis of G6PD Deficiency: Implications for Drug Safety in Thailand

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.
ABSTRACT Glucose‐6‐phosphate dehydrogenase (G6PD) deficiency holds critical health concerns, particularly due to its association with drug‐induced hemolysis triggered by medications such as antimalarials. This condition poses significant risks in malaria‐endemic regions where the prevalence and genetic diversity of G6PD deficiency further complicate ...
Natnicha Pengsuk   +6 more
wiley   +1 more source

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