Results 1 to 10 of about 7,900 (206)

Effects of Repetitive Transcranial Magnetic Stimulation on Pallidum GABAergic Neurons and Motor Function in Rat Models of Kernicterus [PDF]

open access: goldBrain Sciences, 2023
Kernicterus is a serious complication of hyperbilirubinemia, caused by neuronal injury due to excessive unconjugated bilirubin (UCB) in specific brain areas.
Nanqin Wang   +5 more
doaj   +4 more sources

MGE-Like Neural Progenitor Cell Survival and Expression of Parvalbumin and Proenkephalin in a Jaundiced Rat Model of Kernicterus [PDF]

open access: goldCell Transplantation, 2022
Kernicterus is a permanent condition caused by brain damage from bilirubin toxicity. Dystonia is one of the most debilitating symptoms of kernicterus and results from damage to the globus pallidus (GP).
Fu-Chen Yang   +4 more
doaj   +2 more sources

The Importance of Neuroimaging Follow-Up in Bilirubin-Induced Encephalopathy: A Clinical Case Review [PDF]

open access: yesBrain Sciences
Introduction: Hyperbilirubinemia in newborns can lead to kernicterus, a severe form of neonatal encephalopathy caused by bilirubin toxicity. Despite timely interventions such as exchange transfusion, kernicterus can still develop, especially in high-risk
Martina Resaz   +5 more
doaj   +2 more sources

Bilirubin encephalopathy (kernicterus) in an adult cat [PDF]

open access: goldJournal of Feline Medicine and Surgery Open Reports, 2019
Case summary An adult cat presented with neurological signs and marked icterus. Clinical pathology tests detected increased serum alkaline phosphatase levels, as well as alanine aminotransferase, total bilirubin, unconjugated bilirubin and conjugated ...
Luís HG Saraiva   +7 more
doaj   +2 more sources

Kernicterus

open access: hybridAutopsy and Case Reports, 2019
Ameer Hamza
doaj   +2 more sources

Exchange Transfusion Trends and Risk Factors for Extreme Neonatal Hyperbilirubinemia over 10 Years in Shiraz, Iran [PDF]

open access: yesIranian Journal of Medical Sciences
Background: Exchange transfusion (ET) is an effective treatment for acute bilirubin encephalopathy and extreme neonatal hyperbilirubinemia (ENH). It can reduce mortality and morbidity.
Fariba Hemmati   +4 more
doaj   +2 more sources

A novel newborn rat kernicterus model created by injecting a bilirubin solution into the cisterna magna.

open access: goldPLoS ONE, 2014
BackgroundKernicterus still occurs around the world; however, the mechanism of bilirubin neurotoxicity remains unclear, and effective treatment strategies are lacking.
Sijie Song   +4 more
doaj   +2 more sources

Developmental outcome of severe neonatal indirect hyperbilirubinemia [PDF]

open access: yesJournal of Research in Clinical Medicine, 2021
Background: Indirect hyperbilirubinemia is one of the most common causes of hospitalization in the neonatal period and its potential association with brain damage is well established.
Manizheh Mostafa Gharehbaghi   +3 more
doaj   +1 more source

Free Bilirubin Induces Neuro-Inflammation in an Induced Pluripotent Stem Cell-Derived Cortical Organoid Model of Crigler-Najjar Syndrome

open access: yesCells, 2023
Bilirubin-induced neurological damage (BIND), which might progress to kernicterus, occurs as a consequence of defects in the bilirubin conjugation machinery, thus enabling albumin-unbound free bilirubin (BF) to cross the blood–brain barrier and ...
Abida Islam Pranty   +2 more
doaj   +1 more source

Perinatal insults and neurodevelopmental disorders may impact Huntington's disease age of diagnosis [PDF]

open access: yes, 2018
Introduction: The age of diagnosis of Huntington's disease (HD) varies among individuals with the same HTT CAG-repeat expansion size. We investigated whether early-life events, like perinatal insults or neurodevelopmental disorders, influence the ...
Anderson, Dg   +10 more
core   +4 more sources

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