"ASSOCIATION BETWEEN TOTAL SERUM BILIRUBIN LEVEL AND MANIFESTATIONS OF KERNICTERUS " [PDF]
Kernicterus (bilirubin induced encephalopathy) is an uncommon disorder with tragic consequences, especially when it affects healthy term and near-term neonates. Appointment of cut off value of total serum bilirubin level that have a safe margin for early
S. Behjati-Ardakani +2 more
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Newborn Metabolic Profile Associated with Hyperbilirubinemia With and Without Kernicterus
Our objective was to assess the relationship between hyperbilirubinemia with and without kernicterus and metabolic profile at newborn screening. Included were 1,693,658 infants divided into a training or testing subset in a ratio of 3:1.
Molly E. McCarthy +7 more
doaj +1 more source
Changes in globus pallidus with (pre)term kernicterus [PDF]
OBJECTIVE: We report serial magnetic resonance (MR) and sonographic behavior of globus pallidus in 5 preterm and 3 term infants with kernicterus and describe the clinical context in very low birth weight preterm infants. On the basis
Barkovich, J. (James) +8 more
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Bilirubin-Induced Transcriptomic Imprinting in Neonatal Hyperbilirubinemia
Recent findings indicated aberrant epigenetic control of the central nervous system (CNS) development in hyperbilirubinemic Gunn rats as an additional cause of cerebellar hypoplasia, the landmark of bilirubin neurotoxicity in rodents.
John Paul Llido +7 more
doaj +1 more source
Recent advances in the management of neonatal jaundice [PDF]
Jon F Watchko Division of Newborn Medicine, Department of Pediatrics, University of Pittsburgh School of Medicine, Magee-Womens Research Institute, Pittsburgh, PA, USA Abstract: Advances in the clinical assessment strategies used to identify neonates at
Watchko, Jon
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Demystifying non-invasive approaches for screening jaundice in low resource settings: a review
All national and international pediatric guidelines universally prescribe meticulous bilirubin screening for neonates as a critical measure to mitigate the incidence of acute bilirubin encephalopathy (ABE) and Kernicterus.
Umme Abiha +3 more
doaj +1 more source
Total and Fractionated Bilirubin during the First Week in the Neonatal Intensive Care Unit [PDF]
Background. Fractionated bilirubin requires more blood (0.6 ml) than total bilirubin alone (0.2 ml). Our focus during the first week in the Neonatal Intensive Care Unit (NICU) is on prevention of Bilirubin Induced Neurologic Dysfunction and kernicterus ...
Ahlers-Schmidt, Carolyn R +2 more
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Dental management of bilirubin encephalopathy patient: A case report and review
Patients with special health care needs often present with compromised oral health for which they need dental treatment. Such patients and often their guardians find it difficult to maintain oral health due to various reasons such as decreased manual ...
Poornima Parameswarappa +3 more
doaj +1 more source
Bilirubin-Induced Neurological Damage: Current and Emerging iPSC-Derived Brain Organoid Models
Bilirubin-induced neurological damage (BIND) has been a subject of studies for decades, yet the molecular mechanisms at the core of this damage remain largely unknown.
Abida Islam Pranty +2 more
doaj +1 more source
Electromyographic Characterization in an Animal model of Dystonia [PDF]
Kernicterus causes damage to the auditory system and the basal ganglia in humans. Although the Gunn rat model of kernicterus has been extensively used to characterize the auditory features, this model has not been utilized to systematically investigate ...
Chaniary, Kunal Dilip
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