Results 21 to 30 of about 7,580 (241)

Free Bilirubin Induces Neuro-Inflammation in an Induced Pluripotent Stem Cell-Derived Cortical Organoid Model of Crigler-Najjar Syndrome

open access: yesCells, 2023
Bilirubin-induced neurological damage (BIND), which might progress to kernicterus, occurs as a consequence of defects in the bilirubin conjugation machinery, thus enabling albumin-unbound free bilirubin (BF) to cross the blood–brain barrier and ...
Abida Islam Pranty   +2 more
doaj   +1 more source

A review of antibiotic safety in pregnancy-2025 update. [PDF]

open access: yesPharmacotherapy
Abstract Antibiotics constitute the majority of prescriptions for women during pregnancy. Common bacterial infections, including urinary tract infections, skin and soft tissue infections, and upper and lower respiratory tract infections, are expected in pregnancy, similar to the general public.
Nguyen J   +8 more
europepmc   +2 more sources

Management of late-preterm and term infants with hyperbilirubinaemia in resource-constrained settings. [PDF]

open access: yes, 2015
Hyperbilirubinaemia is a ubiquitous transitional morbidity in the vast majority of newborns and a leading cause of hospitalisation in the first week of life worldwide.
Boo, Nem-Yun   +7 more
core   +2 more sources

Genetic Association of UGT1A1 Promoter Variants (c.-3279T>G and c.-3156G>A) with Neonatal Hyperbili-rubinemia in an Iranian Population [PDF]

open access: yesIranian Journal of Neonatology, 2021
Background: Several studies have reported that two promoter variants (c.-3279T>G and c.-3156G>A) in UDP-glucuronosyltransferase (UGT1A1) gene may contribute to neonatal hyperbilirubinemia.
Nasim Pouralizadeh   +6 more
doaj   +1 more source

Management challenges in the treatment of severe hyperbilirubinemia in low- and middle-income countries: Encouraging advancements, remaining gaps, and future opportunities

open access: yesFrontiers in Pediatrics, 2023
Neonatal jaundice (NJ) is common in newborn infants. Severe NJ (SNJ) has potentially negative neurological sequelae that are largely preventable in high resource settings if timely diagnosis and treatment are provided. Advancements in NJ care in low- and
Katherine M. Satrom   +4 more
doaj   +1 more source

Brainstem auditory evoked responses in an equine patient population. Part II: foals. [PDF]

open access: yes, 2014
BackgroundReports of the use of brainstem auditory evoked response (BAER) as a diagnostic modality in foals have been limited.Hypothesis/objectivesTo describe BAER findings and associated causes of hearing loss in foals.AnimalsStudy group 18 foals (15 ...
Aleman, M   +3 more
core   +1 more source

The Causes and Risk Factors in Patients with Kernicterus Referred to the Clinic of Pediatric Neurology during the Years 2011 to 2016

open access: yesمجله دانشکده پزشکی اصفهان, 2018
Background: Neonatal jaundice has potentially severe side effects such as kernicterus. Prevention of kernicterus and hyperbilirubinemia is based on finding neonates with risk factors and starting treatment as soon as possible. Therefore, this study aimed
Jafar Nasiri   +3 more
doaj   +1 more source

Changes in globus pallidus with (pre)term kernicterus [PDF]

open access: yes, 2003
OBJECTIVE: We report serial magnetic resonance (MR) and sonographic behavior of globus pallidus in 5 preterm and 3 term infants with kernicterus and describe the clinical context in very low birth weight preterm infants. On the basis
Barkovich, J. (James)   +8 more
core   +1 more source

Perinatal insults and neurodevelopmental disorders may impact Huntington's disease age of diagnosis [PDF]

open access: yes, 2018
Introduction: The age of diagnosis of Huntington's disease (HD) varies among individuals with the same HTT CAG-repeat expansion size. We investigated whether early-life events, like perinatal insults or neurodevelopmental disorders, influence the ...
Anderson, Dg   +10 more
core   +4 more sources

"ASSOCIATION BETWEEN TOTAL SERUM BILIRUBIN LEVEL AND MANIFESTATIONS OF KERNICTERUS " [PDF]

open access: yesActa Medica Iranica, 2006
Kernicterus (bilirubin induced encephalopathy) is an uncommon disorder with tragic consequences, especially when it affects healthy term and near-term neonates. Appointment of cut off value of total serum bilirubin level that have a safe margin for early
S. Behjati-Ardakani   +2 more
doaj   +1 more source

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