Results 11 to 20 of about 290,727 (340)

Remifentanil-ketamine vs. propofol-ketamine for sedation in pediatric patients undergoing colonoscopy: A randomized clinical trial [PDF]

Revista Brasileira de Anestesiologia, 2018
Background and objectives: Pediatric patients frequently require deep sedation or general anesthesia for colonoscopy. This study was designed to compare the sedative efficacy of remifentanil-ketamine combination with propofol-ketamine combination in ...
Feride Karacaer, Ebru Biricik, Murat Ilgınel, Çağatay Küçükbingöz, Mehmet Ağın, Gökhan Tümgör, Yasemin Güneş, Dilek Özcengiz   +7 more
doaj   +3 more sources

Determination of Diffusion Kinetics of Ketamine in Brain Tissue: Implications for in vitro Mechanistic Studies of Drug Actions

Frontiers in Neuroscience, 2021
Ketamine has been in use for over 50 years as a general anesthetic, acting primarily through blockade of N-methyl-D-aspartate receptors in the brain. Recent studies have demonstrated that ketamine also acts as a potent and rapid-acting antidepressant ...
Zachary Geiger, Brett VanVeller, Zarin Lopez, Abdel K. Harrata, Kathryn Battani, Lauren Wegman-Points, Li-Lian Yuan   +6 more
doaj   +1 more source

Sleep quality among individuals with ketamine use and the mediating role of craving

Scientific Reports, 2020
Sleep problems are common in Taiwan. Poor sleep may be associated with many illnesses, including substance use disorders. Ketamine use disorder has significantly increased in Taiwan in recent years and may lead to physical and cognitive problems. Craving
Cheng-Fang Yen, Huang-Chi Lin, Chih-Hung Ko, Hung-Chi Wu, Chih-Yao Hsu, Peng-Wei Wang   +5 more
doaj   +1 more source

Ketamine for pain [PDF]

F1000Research, 2017
The efficacy of theN-methyl-D-aspartate receptor antagonist ketamine as an analgesic agent is still under debate, especially for indications such as chronic pain. To understand the efficacy of ketamine for relief of pain, we performed a literature search for relevant narrative and systematic reviews and meta-analyses.
Kelly Jonkman, Albert Dahan, Tine van de Donk, Leon Aarts, Marieke Niesters, Monique van Velzen   +5 more
openaire   +3 more sources

Ketamine infusion as a sedative-analgesic in severe ARDS (KISS)

Journal of Community Hospital Internal Medicine Perspectives, 2021
Rationale Ketamine has been used as a sedative analgesic in trauma setting, but data regarding its efficacy and safety is lacking in severe ARDS.
Ramakanth Pata, Pagali Sandeep, Htun Min Aung, Meet J Patel, Tsering Dolkar, Nway Nway, Kosuru Bhanu, Abolfazl Ahmady, Roudabeh Kiani, Ramaiah Swaroop, Frances Schmidt, Danilo Enriquez   +11 more
doaj   +1 more source

A survey of drug liking and cravings in patients using sublingual or intranasal ketamine for treatment resistant depression: A preliminary evaluation of real world addictive potential

Frontiers in Psychiatry, 2022
Ketamine has gained rapid popularity as a treatment option for treatment resistant depression (TRD). Though seen only in limited contexts, ketamine is a potential drug of abuse, addiction and diversion.
Brittany Chubbs, Jay Wang, Shaina Archer, Carson Chrenek, Atul Khullar, Michael Wolowyk, Jennifer Swainson   +6 more
doaj   +1 more source

Restoration of Sp4 in Forebrain GABAergic Neurons Rescues Hypersensitivity to Ketamine in Sp4 Hypomorphic Mice. [PDF]

, 2015
BackgroundKetamine produces schizophrenia-like behavioral phenotypes in healthy people. Prolonged ketamine effects and exacerbation of symptoms after the administration of ketamine have been observed in patients with schizophrenia.
Buell, Mahalah R, Geyer, Mark A, Higa, Kerin K, Ji, Baohu, Powell, Susan B, Risbrough, Victoria B, Young, Jared W, Zhou, Xianjin   +7 more
core   +1 more source

Subanesthetic ketamine treatment promotes abnormal interactions between neural subsystems and alters the properties of functional brain networks [PDF]

, 2014
Acute treatment with subanesthetic ketamine, a non-competitive N-methyl-D-aspartic acid (NMDA) receptor antagonist, is widely utilized as a translational model for schizophrenia. However, how acute NMDA receptor blockade impacts on brain functioning at a
A Bifone, A Marsman, A Nikiforuk, A Stuchlik, A Verma, AC Lahti, AK Malhotra, AS Meyer-Lindenberg, B Moghaddam, BM Roberts, Brian J Morris, C Chih-Liang, C Corradi-Dell'Acqua, C De la Fuente-Sandoval, C Mirjana, Carsten M. Klingner, CJA Morgan, DC D’Souza, Desmond J Higham, DS Bassett, FR Sharp, FX Vollenweider, FX Vollenweider, G Paxinos, GD Honey, GE Duncan, H Metzer, J Cosgrove, J McCulloch, JA Saunders, JD Jentsch, JH Krystal, JH Krystal, JJ Kim, JM McNally, Judith A Pratt, JW Langsjo, JW Moore, K Hill, K Skoblenick, L Deserno, LJ Steward, M Amargos-Bosch, M Hauser, M Irifune, M Niesters, Martin McDonald, ME Jackson, ME Lynall, N Dawson, N Dawson, N Dawson, N Dawson, N Lindefors, N Pitsikas, ND Woodward, Neil Dawson, NR Driesen, R Galci, R Schlösser, RC Welsh, S Benetti, S Marenco, S Micheloyannis, S Miyamoto, SA Spence, SM Cochran, SP Kulikova, SY Yang, T Kos, T Kubota, Tatsunobu Natsubori, VP Bakshi, X Xiao, Y Li, Y Liu, Y Zhang, Y Zhou   +77 more
core   +1 more source

Intravenous ketamine for subacute treatment of refractory chronic migraine: a case series. [PDF]

, 2016
BACKGROUND: Refractory migraine is a challenging condition with great impact on health related quality of life. Intravenous (IV) ketamine has been previously used to treat various refractory pain conditions.
Ashina, Sait, Lauritsen, Clinton, Lipton, Richard B., Mazuera, Santiago   +3 more
core   +3 more sources

Activation of σ1-Receptors by R-Ketamine May Enhance the Antidepressant Effect of S-Ketamine

Biomedicines, 2023
Ketamine is a racemic mixture composed of two enantiomers, S-ketamine and R-ketamine. In preclinical studies, both enantiomers have exhibited antidepressant effects, but these effects are attributed to distinct pharmacological activities.
Hans O. Kalkman
doaj   +1 more source