Results 11 to 20 of about 235,967 (343)

Craving for Ketamine and Its Relationship With Clinical Outcome Indicators in Males With Ketamine Use Disorder

Frontiers in Psychiatry, 2021
Background: Craving is considered a hallmark of substance use disorder and is one of the criteria of substance use disorder. The Desires for Drug Questionnaire (DDQ) is a widely used questionnaire to assess craving for heroin. This study aimed to examine
Peng-Wei Wang, Peng-Wei Wang, Huang-Chi Lin, Huang-Chi Lin, Tai-Ling Liu, Tai-Ling Liu, Chih-Yao Hsu, Yu-Yi Yang, Hung-Chi Wu, Cheng-Fang Yen, Cheng-Fang Yen   +10 more
doaj   +1 more source

Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation.

American Journal of Psychiatry, 2021
Replicated international studies have underscored the human and societal costs associated with major depressive disorder. Despite the proven efficacy of monoamine-based antidepressants in major depression, the majority of treated individuals fail to ...
R. McIntyre, J. Rosenblat, C. Nemeroff, G. Sanacora, J. Murrough, M. Berk, E. Brietzke, S. Dodd, P. Gorwood, R. Ho, D. Iosifescu, C. L. López Jaramillo, S. Kasper, Kevin Kratiuk, J. G. Lee, Yena Lee, L. Lui, R. Mansur, G. Papakostas, Mehala Subramaniapillai, M. Thase, E. Vieta, A. Young, C. Zarate, S. Stahl   +24 more
semanticscholar   +1 more source

Multidisciplinary development of guidelines for ketamine treatment for treatment-resistant major depression disorder for use by adult specialist mental health services in New Zealand

BJPsych Open, 2023
Background The evidence base for racemic ketamine treatment for treatment-resistant major depressive disorder (TRD) continues to expand, but there are major challenges translating this evidence base into routine clinical care.
Ben Beaglehole, Paul Glue, Mike Clarke, Richard Porter   +3 more
doaj   +1 more source

...such as ketamine [PDF]

BMJ, 1996
EDITOR,—There is increasing concern over the toxic1 and neurodegenerative2 effects of ecstasy, and further research is clearly required. Potential hazards can also, however, arise through use of tablets sold as ecstasy that contain substances other than ecstasy, such as ketamine. Ketamine is an anaesthetic agent with a rapid action that has medical and
Shewan, David, Dalgarno, Phil, King, Leslie A.   +2 more
openaire   +3 more sources

NMDA Receptor Glycine Binding Site Modulators for Prevention and Treatment of Ketamine Use Disorder

Pharmaceuticals, 2023
Ketamine offers a fast-acting approach to relieving treatment-resistant depression, but its abuse potential is an issue of concern. As ketamine is a noncompetitive N-methyl-D-aspartate receptor (NMDAR) ion channel blocker, modulation of NMDAR might be an
Yu-Chin Hsiao, Mei-Yi Lee, Ming-Huan Chan, Hwei-Hsien Chen   +3 more
doaj   +1 more source

Ketamine for the acute treatment of severe suicidal ideation: double blind, randomised placebo controlled trial

British medical journal, 2022
Objective To confirm the rapid onset anti-suicidal benefits of ketamine in the short term and at six weeks, overall and according to diagnostic group. Design Prospective, double blind, superiority, randomised placebo controlled trial.
M. Abbar, C. Demattei, W. El-Hage, P. Llorca, L. Samalin, Pierre Demaricourt, R. Gaillard, P. Courtet, G. Vaiva, P. Gorwood, Pascale Fabbro, F. Jollant   +11 more
semanticscholar   +1 more source

Severe Encephalatrophy and Related Disorders From Long-Term Ketamine Abuse: A Case Report and Literature Review

Frontiers in Psychiatry, 2021
Ketamine is a glutamate N-methyl D-aspartate receptor antagonist and an anaesthetic agent that has been effectively used to treat depression. However, ketamine has also been increasingly used for recreational purposes.
Linying Liu, Haijian Huang, Haijian Huang, Yongbin Li, Ruochen Zhang, Ruochen Zhang, Yongbao Wei, Yongbao Wei, Weiwei Wu   +8 more
doaj   +1 more source

Adjunctive Ketamine With Relapse Prevention-Based Psychological Therapy in the Treatment of Alcohol Use Disorder.

American Journal of Psychiatry, 2022
OBJECTIVE Early evidence suggests that ketamine may be an effective treatment to sustain abstinence from alcohol. The authors investigated the safety and efficacy of ketamine compared with placebo in increasing abstinence in patients with alcohol use ...
M. Grabski, A. McAndrew, Will Lawn, Beth Marsh, Laura Raymen, Tobias Stevens, Lorna Hardy, F. Warren, M. Bloomfield, A. Borissova, Emily L. Maschauer, Rupert Broomby, Robert Price, R. Coathup, D. Gilhooly, Edward R. Palmer, R. Gordon-Williams, R. Hill, Jennifer S. Harris, O. M. Mollaahmetoglu, H. Curran, B. Brandner, A. Lingford-Hughes, C. Morgan   +23 more
semanticscholar   +1 more source

Ketamine treatment for depression: a review

Discover Mental Health, 2022
This manuscript reviews the clinical evidence regarding single-dose intravenous (IV) administration of the novel glutamatergic modulator racemic (R,S)-ketamine (hereafter referred to as ketamine) as well as its S-enantiomer, intranasal esketamine, for ...
Mani Yavi, H. Lee, I. Henter, Lawrence T. Park, C. Zarate   +4 more
semanticscholar   +1 more source

Remifentanil-ketamine vs. propofol-ketamine for sedation in pediatric patients undergoing colonoscopy: A randomized clinical trial [PDF]

Revista Brasileira de Anestesiologia, 2018
Background and objectives: Pediatric patients frequently require deep sedation or general anesthesia for colonoscopy. This study was designed to compare the sedative efficacy of remifentanil-ketamine combination with propofol-ketamine combination in ...
Feride Karacaer, Ebru Biricik, Murat Ilgınel, Çağatay Küçükbingöz, Mehmet Ağın, Gökhan Tümgör, Yasemin Güneş, Dilek Özcengiz   +7 more
doaj   +3 more sources