Results 31 to 40 of about 276,611 (294)

Retrospective Study of Midazolam Protocol for Prehospital Behavioral Emergencies [PDF]

, 2020
Introduction: Agitated patients in the prehospital setting pose challenges for both patient care and emergency medical services (EMS) provider safety. Midazolam is frequently used to control agitation in the emergency department setting; however, limited
Huebinger, Ryan M., Markul, Eddie, Pearlman, Kenneth S., Richards, Christopher T., Stein-Spencer, Leslee, Tataris, Katie L., Weber, Joseph M., Zaidi, Hashim Q.   +7 more
core   +1 more source

Efficacy of propofol versus ketamine in modified electroconvulsive therapy: A prospective randomized control trial

Journal of Acute Disease, 2022
Objective: To investigate the effects of propofol and ketamine on seizure duration, hemodynamics, and recovery of electroconvulsive therapy (ECT).
Debarshi Guha, Kiran Sheshadri, Shalendra Singh, Sonia Bhan   +3 more
doaj   +1 more source

The collective lie in ketamine therapy: a call to realign clinical practice with neurobiology

Frontiers in Psychiatry
In recent years, ketamine therapy has become increasingly entangled with psychedelic culture, leading to widespread misinterpretation of its therapeutic mechanism.
Charles Miller, Bryan Lopes, Anna McCurdy   +2 more
doaj   +1 more source

Biosensors Show the Pharmacokinetics of S-Ketamine in the Endoplasmic Reticulum

Frontiers in Cellular Neuroscience, 2019
The target for the “rapid” (<24 h) antidepressant effects of S-ketamine is unknown, vitiating programs to rationally develop more effective rapid antidepressants.
Kallol Bera, Aron Kamajaya, Amol V. Shivange, Anand K. Muthusamy, Anand K. Muthusamy, Aaron L. Nichols, Aaron L. Nichols, Philip M. Borden, Stephen Grant, Janice Jeon, Elaine Lin, Ishak Bishara, Theodore M. Chin, Bruce N. Cohen, Charlene H. Kim, Elizabeth K. Unger, Lin Tian, Jonathan S. Marvin, Loren L. Looger, Henry A. Lester   +19 more
doaj   +1 more source

Considerations for physicians using ketamine for sedation of children in emergency departments [PDF]

Clinical and Experimental Emergency Medicine, 2017
Objective Ketamine use in emergency departments (EDs) for procedural sedation and analgesia is becoming increasingly common. However, few studies have examined patient factors related to adverse events associated with ketamine.
Woo Sung Kim, Ji Yeon Ku, Hanbyul Choi, Hyo Jeong Choi, Ho Jung Kim, Bora Lee   +5 more
doaj   +1 more source

Role of N-methyl-D-aspartate receptors in action-based predictive coding deficits in schizophrenia [PDF]

, 2017
Published in final edited form as:Biol Psychiatry. 2017 March 15; 81(6): 514–524. doi:10.1016/j.biopsych.2016.06.019.BACKGROUND: Recent theoretical models of schizophrenia posit that dysfunction of the neural mechanisms subserving predictive coding ...
Ford, Judith M., Gunduz-Bruce, Handan, Jaeger, Judith, Kort, Naomi S., Krystal, John H., Mathalon, Daniel H., Reinhart, Robert M.G., Roach, Brian J.   +7 more
core   +1 more source

Ketamine Assisted EMDR Therapy™ for PTSD: investigating the synergistic effects of pharmacotherapy and psychotherapy

European Journal of Psychotraumatology
Background: Posttraumatic stress disorder (PTSD) is associated with maladaptive memory reconsolidation and overgeneralized fear responses. EMDR therapy promotes trauma reprocessing by activating the brain’s intrinsic memory reconsolidation mechanism ...
Michele Topel, Danielle Ciccone
doaj   +1 more source

Effects of an intravenous ketamine infusion on inflammatory cytokine levels in male and female Sprague–Dawley rats

Journal of Neuroinflammation, 2022
Background Ketamine, a multimodal dissociative anesthetic drug, is widely used as an analgesic following traumatic injury. Although ketamine may produce anti-inflammatory effects when administered after injury, the immunomodulatory properties of ...
Haley F. Spencer, Rina Y. Berman, Martin Boese, Michael Zhang, Sharon Y. Kim, Kennett D. Radford, Kwang H. Choi   +6 more
doaj   +1 more source

Using transcranial direct-current stimulation (tDCS) to understand cognitive processing [PDF]

, 2016
Noninvasive brain stimulation methods are becoming increasingly common tools in the kit of the cognitive scientist. In particular, transcranial direct-current stimulation (tDCS) is showing great promise as a tool to causally manipulate the brain and ...
Cosman, Josh D., Fukuda, Keisuke, Reinhart, Robert M.G., Woodman, Geoffrey F.   +3 more
core   +1 more source

Psychedelics Promote Structural and Functional Neural Plasticity. [PDF]

, 2018
Atrophy of neurons in the prefrontal cortex (PFC) plays a key role in the pathophysiology of depression and related disorders. The ability to promote both structural and functional plasticity in the PFC has been hypothesized to underlie the fast ...
Barragan, Eden V, Burbach, Kyle F, Cameron, Lindsay P, Dennis, Megan Y, Duim, Whitney C, Gray, John A, Greb, Alexandra C, Ly, Calvin, McAllister, A Kimberley, Olson, David E, Ori-McKenney, Kassandra M, Paddy, Michael R, Soltanzadeh Zarandi, Sina, Sood, Alexander, Wilson, Paige C, Wong, Jonathan M   +15 more
core   +2 more sources